DE69828241D1 - Diagnostisches Mittel zur Leberfunktion - Google Patents

Diagnostisches Mittel zur Leberfunktion

Info

Publication number
DE69828241D1
DE69828241D1 DE69828241T DE69828241T DE69828241D1 DE 69828241 D1 DE69828241 D1 DE 69828241D1 DE 69828241 T DE69828241 T DE 69828241T DE 69828241 T DE69828241 T DE 69828241T DE 69828241 D1 DE69828241 D1 DE 69828241D1
Authority
DE
Germany
Prior art keywords
diagnostic agent
liver function
liver
diagnostic
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69828241T
Other languages
English (en)
Other versions
DE69828241T2 (de
Inventor
Kohno Tadashi
Hosoi Isaburo
Ohshima Junko
Ito Asuka
Shibata Kunihiko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Gas Co Ltd
Original Assignee
Tokyo Gas Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP27255897A external-priority patent/JP4007647B2/ja
Priority claimed from JP27288997A external-priority patent/JP4007649B2/ja
Priority claimed from JP27273797A external-priority patent/JP4007648B2/ja
Priority claimed from JP34126297A external-priority patent/JP4007660B2/ja
Priority claimed from JP00641198A external-priority patent/JP4007664B2/ja
Priority claimed from JP02473398A external-priority patent/JP4007669B2/ja
Application filed by Tokyo Gas Co Ltd filed Critical Tokyo Gas Co Ltd
Application granted granted Critical
Publication of DE69828241D1 publication Critical patent/DE69828241D1/de
Publication of DE69828241T2 publication Critical patent/DE69828241T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Atmospheric Sciences (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69828241T 1997-10-06 1998-10-05 Diagnostisches Mittel zur Leberfunktion Expired - Lifetime DE69828241T2 (de)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
JP27273797 1997-10-06
JP27288997 1997-10-06
JP27255897A JP4007647B2 (ja) 1997-10-06 1997-10-06 肝機能診断剤
JP27288997A JP4007649B2 (ja) 1997-10-06 1997-10-06 肝機能診断剤
JP27255897 1997-10-06
JP27273797A JP4007648B2 (ja) 1997-10-06 1997-10-06 肝機能診断剤
JP28866097 1997-10-21
JP28866097 1997-10-21
JP34126297 1997-12-11
JP34126297A JP4007660B2 (ja) 1997-12-11 1997-12-11 肝機能診断剤
JP641198 1998-01-16
JP00641198A JP4007664B2 (ja) 1998-01-16 1998-01-16 肝機能診断剤
JP2473398 1998-02-05
JP02473398A JP4007669B2 (ja) 1997-10-21 1998-02-05 肝機能診断剤

Publications (2)

Publication Number Publication Date
DE69828241D1 true DE69828241D1 (de) 2005-01-27
DE69828241T2 DE69828241T2 (de) 2005-12-08

Family

ID=27563357

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69828241T Expired - Lifetime DE69828241T2 (de) 1997-10-06 1998-10-05 Diagnostisches Mittel zur Leberfunktion
DE69835546T Expired - Lifetime DE69835546T2 (de) 1997-10-06 1998-10-05 Diagnostisches Mittel zur Leberfunktion

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69835546T Expired - Lifetime DE69835546T2 (de) 1997-10-06 1998-10-05 Diagnostisches Mittel zur Leberfunktion

Country Status (5)

Country Link
US (1) US6071245A (de)
EP (2) EP0911040B1 (de)
CA (1) CA2249173C (de)
DE (2) DE69828241T2 (de)
ES (2) ES2235297T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2250485C (en) * 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6905668B1 (en) * 1998-09-25 2005-06-14 Tokyo Gas Company Limited Diagnostic agents for pancreatic exocrine function
US6740305B1 (en) * 1999-04-09 2004-05-25 Xanthus Life Scienes, Inc. Assessment of gastric emptying disorders
US6432382B1 (en) * 2000-10-20 2002-08-13 The Nemours Foundation Measurement of gastric emptying using stable isotopes
US6521210B2 (en) * 2000-12-13 2003-02-18 Archimedes Technology Group, Inc. Method for imaging malignant tumors using carbon 13 with MRI
GB0106923D0 (en) * 2001-03-20 2001-05-09 Univ Dundee Liver function test
ITMI20010885A1 (it) * 2001-04-27 2002-10-27 Eurospital S P A Metodo per la determinazione di neoplasie gastriche ed esofagee
EP1302465A1 (de) * 2001-10-11 2003-04-16 BRACCO IMAGING S.p.A. Verbesserte MRI-Bildgebung mittels umkehrbares binding zu einem paramagnetischen Komplex
AU2002365268B2 (en) * 2001-10-24 2008-02-28 The Regents Of The University Of California Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled water
CA2475924C (en) * 2002-02-12 2016-03-29 The Regents Of The University Of California Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation
US6544954B1 (en) 2002-02-19 2003-04-08 Oliver Yoa-Pu Hu Stable galactose injection solutions
AU2003234688A1 (en) * 2002-04-05 2003-10-27 The Regents Of The University Of California Method for isolating and measuring proliferation of long-term label retaining cells and stem cells
EP1546364A4 (de) 2002-07-30 2006-09-06 Univ California Verfahren zur automatischen messung im grossmassstab der molekularen flussgeschwindigkeiten des proteoms oder des organoms mittels massenspektrometrie
WO2004021863A2 (en) * 2002-09-04 2004-03-18 The Regents Of The University Of California Methods for measuring rates of replication and death of nfectious microbial agents in an infected host organism
SG149699A1 (en) * 2002-09-13 2009-02-27 Univ California Methods for measuring rates of reverse cholesterol transport in vivo, as an index of anti-atherogenesis
AU2003275037A1 (en) * 2002-09-16 2004-04-30 The Regents Of The University Of California Biochemical methods for measuring metabolic fitness of tissues or whole organisms
US20070248540A1 (en) * 2002-09-16 2007-10-25 The Regents Of The University Of California Biochemical methods for measuring metabolic fitness of tissues or whole organisms
EP1558293A4 (de) * 2002-11-04 2006-10-25 Univ California Deuterierte glucose- oder fetttoleranztests für die messung des stoffwechsels vonzuckern oder fettsüuren im k rper mit hohem durchsatz
US7262020B2 (en) * 2003-07-03 2007-08-28 The Regents Of The University Of California Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol
US20050202406A1 (en) 2003-11-25 2005-09-15 The Regents Of The University Of California Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
TW200538738A (en) 2004-02-20 2005-12-01 Univ California Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
AU2005222430A1 (en) * 2004-03-11 2005-09-22 The Regents Of University Of California Temporal or spatial characterization of biosynthetic events in living organisms by isotopic fingerprinting under conditions of imposed isotopic gradients
WO2005094327A2 (en) * 2004-03-29 2005-10-13 The Regents Of The University Of California Isolation of epithelial cells or their biochemical contents from excreta after in vivo isotopic labeling
US20060251576A1 (en) * 2005-05-03 2006-11-09 The Regents Of The University Of California Methods for measuring cholesterol metabolism and transport
TW200711660A (en) 2005-06-10 2007-04-01 Univ California Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development
EP1898961B1 (de) * 2005-06-30 2014-02-26 Otsuka America Pharmaceutical, Inc. Verfahren zur individualisierung der levodopa/carbidopa-therapie mit einem atemtest
US8512258B2 (en) * 2005-11-11 2013-08-20 Exalenz Bioscience Ltd. Breath test device and method
US8622920B2 (en) * 2005-11-11 2014-01-07 Exalenz Bioscience Ltd. Breath test device and method
WO2007129574A1 (ja) * 2006-05-01 2007-11-15 Tokyo Gas Co., Ltd. 胃排出機能及び／又は小腸吸収能を評価するための診断剤
WO2009124250A1 (en) * 2008-04-03 2009-10-08 The Trustees Of The University Of Pennsylvania Compositions and methods for detecting tricarboxylic acid (tca) metabolic flux
DK2598174T3 (da) 2010-07-30 2019-06-24 Smartdyelivery Gmbh Målemetode til bestemmelse af en organfunktion
WO2012140660A1 (en) 2011-04-14 2012-10-18 Exalenz Bioscience Ltd. Methods for diagnosis, prognosis, monitoring and treatment of hepatocellular carcinoma
JP2014526685A (ja) 2011-09-08 2014-10-06 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 代謝流量測定、画像化、および顕微鏡法
EP3435088A1 (de) 2011-12-07 2019-01-30 GlaxoSmithKline LLC Verfahren zur bestimmung der skelettmuskelmasse des gesamten körpers
US9134319B2 (en) 2013-03-15 2015-09-15 The Regents Of The University Of California Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
US9697994B1 (en) 2015-04-09 2017-07-04 Ricarez Biosciences, LLC Use of stable label compounds with accelerator mass spectrometry
JP6956977B2 (ja) 2016-11-11 2021-11-02 大塚製薬株式会社 肝の糖取込み能評価方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164308A (en) * 1990-05-21 1992-11-17 Martek Corporation Preparation of labelled triglyceride oils by cultivation of microorganisms
US5413917A (en) * 1990-07-18 1995-05-09 Board Of Regents, The University Of Texas System Method of determining sources of acetyl-CoA under nonsteady-state conditions
IL101120A (en) * 1991-03-08 1996-10-31 Tokyo Gas Co Ltd Preparation of compounds marked C31
US5715835A (en) * 1992-11-19 1998-02-10 Anticancer, Inc. Methods for treating and reducing the potential for cardiovascular disease using methioninase compositions
US5386832A (en) * 1993-06-11 1995-02-07 New England Deaconess Hospital Liver function breath test using aromatic amino acids
US5847193A (en) * 1995-03-24 1998-12-08 Watanabe; Yasuyoshi Labelled compound
ES2186844T3 (es) * 1996-08-27 2003-05-16 Tokyo Gas Co Ltd Agentes de diagnostico para la diabetes.

Also Published As

Publication number Publication date
EP0911040B1 (de) 2004-12-22
CA2249173A1 (en) 1999-04-06
CA2249173C (en) 2008-12-16
DE69828241T2 (de) 2005-12-08
ES2235297T3 (es) 2005-07-01
EP1304125A2 (de) 2003-04-23
US6071245A (en) 2000-06-06
EP1304125A3 (de) 2003-11-26
ES2269596T3 (es) 2007-04-01
EP0911040A1 (de) 1999-04-28
DE69835546D1 (de) 2006-09-21
EP1304125B1 (de) 2006-08-09
DE69835546T2 (de) 2007-08-16

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Legal Events

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