DE69820973T2 - Biphasige arzneimitteldosierungsform aus vielen komponenten, die stoffe enthält, die die verteilung der arzneimittel beeinflussen können - Google Patents

Biphasige arzneimitteldosierungsform aus vielen komponenten, die stoffe enthält, die die verteilung der arzneimittel beeinflussen können Download PDF

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Publication number
DE69820973T2
DE69820973T2 DE69820973T DE69820973T DE69820973T2 DE 69820973 T2 DE69820973 T2 DE 69820973T2 DE 69820973 T DE69820973 T DE 69820973T DE 69820973 T DE69820973 T DE 69820973T DE 69820973 T2 DE69820973 T2 DE 69820973T2
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DE
Germany
Prior art keywords
weight
active ingredient
oil
composition
distribution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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DE69820973T
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German (de)
English (en)
Other versions
DE69820973D1 (de
Inventor
Pierandrea Esposito
Nicoletta Coceani
Dorly Maria DEL CURTO
Fabio Carli
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Adare Pharmaceuticals SRL
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Eurand International SpA
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Publication of DE69820973D1 publication Critical patent/DE69820973D1/de
Publication of DE69820973T2 publication Critical patent/DE69820973T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DE69820973T 1997-05-13 1998-05-13 Biphasige arzneimitteldosierungsform aus vielen komponenten, die stoffe enthält, die die verteilung der arzneimittel beeinflussen können Expired - Fee Related DE69820973T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97MI001115A IT1291362B1 (it) 1997-05-13 1997-05-13 Composizioni farmaceutiche multicomponente bifasiche contenenti sostanze atte a modificare la partizione dei principi attivi
ITMI971115 1997-05-13
PCT/EP1998/002846 WO1998051280A1 (en) 1997-05-13 1998-05-13 Biphasic multicomponent pharmaceutical dosage forms containing substances able to modify the partitioning of drugs

Publications (2)

Publication Number Publication Date
DE69820973D1 DE69820973D1 (de) 2004-02-12
DE69820973T2 true DE69820973T2 (de) 2004-12-23

Family

ID=11377121

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69820973T Expired - Fee Related DE69820973T2 (de) 1997-05-13 1998-05-13 Biphasige arzneimitteldosierungsform aus vielen komponenten, die stoffe enthält, die die verteilung der arzneimittel beeinflussen können

Country Status (9)

Country Link
US (1) US6495160B2 (enExample)
EP (1) EP0917457B1 (enExample)
JP (1) JP2001502358A (enExample)
AT (1) ATE257370T1 (enExample)
AU (1) AU7912598A (enExample)
DE (1) DE69820973T2 (enExample)
ES (1) ES2213908T3 (enExample)
IT (1) IT1291362B1 (enExample)
WO (1) WO1998051280A1 (enExample)

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US8580954B2 (en) 2006-03-28 2013-11-12 Hospira, Inc. Formulations of low dose diclofenac and beta-cyclodextrin

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JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
JP2003055204A (ja) * 2001-08-21 2003-02-26 Sansho Iyaku Kk ユビデカレノン組成物及び同組成物を内容物とするカプセル
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
CA2486909A1 (en) * 2002-05-23 2003-12-04 Umd, Inc. Compositions and method for transmucosal drug delivery and cryoprotection
AU2003241134A1 (en) * 2002-06-20 2004-01-06 Amnon Sintov Transdermal drug delivery system
US7001893B2 (en) * 2002-10-28 2006-02-21 Council Of Scientific And Industrial Research Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US6635654B1 (en) 2003-01-09 2003-10-21 Allergan, Inc. Ophthalmic compositions containing loratadine
FR2851918B1 (fr) * 2003-03-06 2006-06-16 Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication
JP4512700B2 (ja) * 2003-06-02 2010-07-28 トーアエイヨー株式会社 アシクロビル含有水溶液製剤
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
JP4866546B2 (ja) * 2004-12-10 2012-02-01 久光製薬株式会社 ジクロフェナク含有乳剤性軟膏剤
US20060177504A1 (en) * 2005-02-08 2006-08-10 Renjit Sundharadas Combination pain medication
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
CN101351196B (zh) * 2005-10-26 2013-07-03 班纳制药公司 作为胶囊填充物的基于亲脂性载体的双重控释基质系统
KR20090010953A (ko) * 2006-03-28 2009-01-30 자블린 파머슈티칼스 인코포레이티드 저 복용량의 비-스테로이드성 항염증성 약물 및 베타-사이클로덱스트린 제형
RU2323716C1 (ru) * 2006-07-10 2008-05-10 Илья Александрович Марков Основа для суппозиториев
RU2322968C1 (ru) * 2006-07-10 2008-04-27 Илья Александрович Марков Суппозитории
DE102007034976A1 (de) 2007-07-26 2009-01-29 Bayer Healthcare Ag Arzneimittel zur transdermalen Anwendung bei Tieren
KR101517415B1 (ko) * 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
EP2434886B1 (en) 2009-05-29 2019-10-16 CyDex Pharmaceuticals, Inc. Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same
SG10201704847WA (en) 2009-10-01 2017-07-28 Adare Pharmaceuticals Inc Orally administered corticosteroid compositions
WO2011067667A2 (en) 2009-12-02 2011-06-09 Eurand Pharmaceuticals Limited Fexofenadine microcapsules and compositions containing them
US20130309218A1 (en) * 2011-01-31 2013-11-21 Wacker Chemie Ag Process for producing aqueous solution containing fat-soluble substance
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CN104363893A (zh) * 2012-03-22 2015-02-18 普雷西恩护肤公司 环糊精系微乳剂及其用于皮肤病的用途
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
AU2015296609A1 (en) 2014-07-29 2016-12-22 Therapeuticsmd, Inc. Transdermal cream
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
EP4112041A1 (en) * 2021-06-30 2023-01-04 GSK Consumer Healthcare SARL Micellar solution comprising diclofenac
US20250040539A1 (en) * 2021-12-17 2025-02-06 Basf Se Composition comprising an antimicrobial agent and a carboxamide
CN116531326B (zh) * 2023-04-26 2023-11-14 广东嘉博制药有限公司 一种阿普米司特的口服乳剂及其制备方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8580954B2 (en) 2006-03-28 2013-11-12 Hospira, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
US8946292B2 (en) 2006-03-28 2015-02-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin

Also Published As

Publication number Publication date
WO1998051280A1 (en) 1998-11-19
EP0917457B1 (en) 2004-01-07
IT1291362B1 (it) 1999-01-07
ES2213908T3 (es) 2004-09-01
ITMI971115A0 (enExample) 1997-05-13
AU7912598A (en) 1998-12-08
US6495160B2 (en) 2002-12-17
JP2001502358A (ja) 2001-02-20
US20020034539A1 (en) 2002-03-21
ITMI971115A1 (it) 1998-11-13
EP0917457A1 (en) 1999-05-26
DE69820973D1 (de) 2004-02-12
ATE257370T1 (de) 2004-01-15

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee