JP2001502358A - 薬物の分配を変化させる事が可能な物質を含む、二相性であり多成分の薬剤の用法 - Google Patents

薬物の分配を変化させる事が可能な物質を含む、二相性であり多成分の薬剤の用法

Info

Publication number
JP2001502358A
JP2001502358A JP10544435A JP54443598A JP2001502358A JP 2001502358 A JP2001502358 A JP 2001502358A JP 10544435 A JP10544435 A JP 10544435A JP 54443598 A JP54443598 A JP 54443598A JP 2001502358 A JP2001502358 A JP 2001502358A
Authority
JP
Japan
Prior art keywords
composition
weight
acid
active ingredient
surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10544435A
Other languages
English (en)
Japanese (ja)
Inventor
ピエランドレア エスポシト
ニコレッタ コチェアニ
クルト マリア ドーリー デル
ファビオ カーリ
Original Assignee
ヴェクターファルマ ソシエタ ペル アチオニ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ヴェクターファルマ ソシエタ ペル アチオニ filed Critical ヴェクターファルマ ソシエタ ペル アチオニ
Publication of JP2001502358A publication Critical patent/JP2001502358A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP10544435A 1997-05-13 1998-05-13 薬物の分配を変化させる事が可能な物質を含む、二相性であり多成分の薬剤の用法 Pending JP2001502358A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97MI001115A IT1291362B1 (it) 1997-05-13 1997-05-13 Composizioni farmaceutiche multicomponente bifasiche contenenti sostanze atte a modificare la partizione dei principi attivi
IT97A001115 1997-05-13
PCT/EP1998/002846 WO1998051280A1 (en) 1997-05-13 1998-05-13 Biphasic multicomponent pharmaceutical dosage forms containing substances able to modify the partitioning of drugs

Publications (1)

Publication Number Publication Date
JP2001502358A true JP2001502358A (ja) 2001-02-20

Family

ID=11377121

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10544435A Pending JP2001502358A (ja) 1997-05-13 1998-05-13 薬物の分配を変化させる事が可能な物質を含む、二相性であり多成分の薬剤の用法

Country Status (9)

Country Link
US (1) US6495160B2 (enExample)
EP (1) EP0917457B1 (enExample)
JP (1) JP2001502358A (enExample)
AT (1) ATE257370T1 (enExample)
AU (1) AU7912598A (enExample)
DE (1) DE69820973T2 (enExample)
ES (1) ES2213908T3 (enExample)
IT (1) IT1291362B1 (enExample)
WO (1) WO1998051280A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004359548A (ja) * 2003-06-02 2004-12-24 Toa Eiyo Ltd アシクロビル含有水溶液製剤
JP2006160707A (ja) * 2004-12-10 2006-06-22 Hisamitsu Medical Kk ジクロフェナク含有乳剤性軟膏剤
JP2006519820A (ja) * 2003-03-06 2006-08-31 ソシエテ ア レスポンサビリテ リミテ ガルニクス イノヴァシオン 生物学的利用能および／または溶解度を増大させるための含浸粉末とその製造方法
JP2009513657A (ja) * 2005-10-26 2009-04-02 バナー ファーマキャプス， インコーポレイテッド カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム
WO2012105546A1 (ja) * 2011-01-31 2012-08-09 株式会社シクロケムバイオ 脂溶性物質を含む水溶液の製造方法

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
IL137559A (en) * 2000-07-27 2006-12-31 Amnon Sintov A system for administering drugs through the skin
JP3962684B2 (ja) * 2000-11-06 2007-08-22 サムヤン コーポレイション 改善された水分吸収能および接着性を有する経皮投与剤
JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
JP2003055204A (ja) * 2001-08-21 2003-02-26 Sansho Iyaku Kk ユビデカレノン組成物及び同組成物を内容物とするカプセル
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
CA2486909A1 (en) * 2002-05-23 2003-12-04 Umd, Inc. Compositions and method for transmucosal drug delivery and cryoprotection
US20050226910A1 (en) * 2002-06-20 2005-10-13 Amnon Sintov Transdermal drug delivery system
US7001893B2 (en) * 2002-10-28 2006-02-21 Council Of Scientific And Industrial Research Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US6635654B1 (en) 2003-01-09 2003-10-21 Allergan, Inc. Ophthalmic compositions containing loratadine
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
WO2006047493A2 (en) 2004-10-21 2006-05-04 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US20060177504A1 (en) * 2005-02-08 2006-08-10 Renjit Sundharadas Combination pain medication
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
MX2008012496A (es) * 2006-03-28 2009-01-07 Javelin Pharmaceuticals Inc Formulaciones de farmacos anti-inflamatorios no esteroidales de baja dosis y beta-ciclodextrina.
EP2522343A1 (en) 2006-03-28 2012-11-14 Javelin Pharmaceuticals, Inc. Formulations of Low Dose Diclofenac and Beta-Cyclodextrin
RU2322968C1 (ru) * 2006-07-10 2008-04-27 Илья Александрович Марков Суппозитории
RU2323716C1 (ru) * 2006-07-10 2008-05-10 Илья Александрович Марков Основа для суппозиториев
DE102007034976A1 (de) 2007-07-26 2009-01-29 Bayer Healthcare Ag Arzneimittel zur transdermalen Anwendung bei Tieren
KR101517415B1 (ko) * 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
KR101522918B1 (ko) 2009-05-29 2015-05-27 사이덱스 파마슈티칼스, 인크. 사이클로덱스트린 유도체를 포함하는 주사용 멜팔란 조성물 및 이의 제조 및 사용 방법
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
KR20150043548A (ko) 2009-10-01 2015-04-22 앱탈리스 파마테크, 인코포레이티드 경구 투여용 코르티코스테로이드 조성물
SG10201407965XA (en) 2009-12-02 2015-02-27 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
WO2013142251A1 (en) * 2012-03-22 2013-09-26 Precision Dermatology, Inc. Cyclodextrin-based microemulsions, and dermatological uses thereof
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
KR20170040209A (ko) 2014-07-29 2017-04-12 쎄러퓨틱스엠디, 인코퍼레이티드 경피 크림
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
US12691128B2 (en) 2019-10-01 2026-07-28 Ellodi Pharmaceuticals, L.P. Methods of treating eosinophilic esophagitis and reducing candidiasis
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
EP4112041A1 (en) * 2021-06-30 2023-01-04 GSK Consumer Healthcare SARL Micellar solution comprising diclofenac
WO2023111296A1 (en) * 2021-12-17 2023-06-22 Basf Se Composition comprising an antimicrobial agent and a carboxamide
CN116531326B (zh) * 2023-04-26 2023-11-14 广东嘉博制药有限公司 一种阿普米司特的口服乳剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6016917A (ja) * 1983-07-08 1985-01-28 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンまたはニフエジピンの軟膏剤
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
JPH06104624B2 (ja) * 1986-05-07 1994-12-21 太郎 小木曽 経皮吸収剤
DE3827561C1 (enExample) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
US5422361A (en) * 1989-12-20 1995-06-06 Schering Corporation Stable cream and lotion bases for lipophilic drug compositions
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5932755A (en) * 1994-06-16 1999-08-03 Kao Corporation Fatty acid ester of etherified polyhydric alcohol
US5747058A (en) * 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006519820A (ja) * 2003-03-06 2006-08-31 ソシエテ ア レスポンサビリテ リミテ ガルニクス イノヴァシオン 生物学的利用能および／または溶解度を増大させるための含浸粉末とその製造方法
JP2004359548A (ja) * 2003-06-02 2004-12-24 Toa Eiyo Ltd アシクロビル含有水溶液製剤
JP2006160707A (ja) * 2004-12-10 2006-06-22 Hisamitsu Medical Kk ジクロフェナク含有乳剤性軟膏剤
JP2009513657A (ja) * 2005-10-26 2009-04-02 バナー ファーマキャプス， インコーポレイテッド カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム
WO2012105546A1 (ja) * 2011-01-31 2012-08-09 株式会社シクロケムバイオ 脂溶性物質を含む水溶液の製造方法
JP5938587B2 (ja) * 2011-01-31 2016-06-22 株式会社シクロケムバイオ 脂溶性物質を含む水溶液の製造方法

Also Published As

Publication number Publication date
EP0917457A1 (en) 1999-05-26
DE69820973D1 (de) 2004-02-12
ES2213908T3 (es) 2004-09-01
ITMI971115A1 (it) 1998-11-13
ATE257370T1 (de) 2004-01-15
DE69820973T2 (de) 2004-12-23
AU7912598A (en) 1998-12-08
EP0917457B1 (en) 2004-01-07
IT1291362B1 (it) 1999-01-07
US6495160B2 (en) 2002-12-17
WO1998051280A1 (en) 1998-11-19
ITMI971115A0 (enExample) 1997-05-13
US20020034539A1 (en) 2002-03-21

Similar Documents

Publication Publication Date Title
EP0917457B1 (en) Biphasic multicomponent pharmaceutical dosage forms containing substances able to modify the partitioning of drugs
JP4173533B2 (ja) 超微小油球体を用いての局部用及び経皮用投与システム
JP4884223B2 (ja) 経皮医薬組成物
EP1265617B1 (fr) Nouvelles compositions estro-progestatives topiques a effet systemique
JP4825305B2 (ja) 経皮吸収製剤
US10016442B2 (en) Estrogen compositions for vaginal administration
CN110545796A (zh) 用于活性化合物的局部递送系统
JP2006008700A (ja) 超微小油球体を用いての局部用及び経皮用投与システム
NO338665B1 (no) Doseringssystem med kontrollert frigivning for nasale anvendelser
AU2010256130A1 (en) Preparation method of drug loaded emulsion
EP1603538A2 (fr) Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication
JPH11502809A (ja) 局所用医薬組成物、その製造方法、およびこの組成物の使用
HU223343B1 (hu) Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US9084818B2 (en) Topical dermal delivery compositions using self assembling nanoparticles with cetylated components
JP4387639B2 (ja) 経皮吸収製剤
RU2362545C2 (ru) Двухжидкостные пены, стабильная дисперсия на их основе и способ ее получения
AU2018435421A1 (en) Topical composition
EP0679392A1 (fr) Nouvelle forme galénique pour l'administration transdermique
CN101217963A (zh) 疏水性药物给药系统及含有疏水性药物的组合物
JP2023525160A (ja) 毛包内への生物活性剤の送達のための組成物
WO2026056754A1 (zh) 一种5α-还原酶抑制剂的含醇乳液及其制备方法和应用
EP2029133B1 (fr) Compositions comprenant au moins un dérivé de l'acide naphtoïque et au moins un agent filmogène, leurs procédés de préparation, et leurs utilisations
WO2009007622A2 (fr) Composition dermatologique comprenant des vésicules lipidiques de calcitriol, son procédé de préparation et son utilisation
EP3302421B1 (fr) Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques
WO2023275003A1 (en) Micellar solution comprising diclofenac