DE69735715T2 - Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird - Google Patents

Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird Download PDF

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Publication number
DE69735715T2
DE69735715T2 DE69735715T DE69735715T DE69735715T2 DE 69735715 T2 DE69735715 T2 DE 69735715T2 DE 69735715 T DE69735715 T DE 69735715T DE 69735715 T DE69735715 T DE 69735715T DE 69735715 T2 DE69735715 T2 DE 69735715T2
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DE
Germany
Prior art keywords
binding protein
choline
choline binding
seq
cbp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69735715T
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German (de)
English (en)
Other versions
DE69735715D1 (de
Inventor
H.Robert New York MASURE
Carsten I. New York ROSENOW
Elaine New York TUOMANEN
Theresa M. New York WIZEMAN
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Rockefeller University
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Rockefeller University
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Application filed by Rockefeller University filed Critical Rockefeller University
Publication of DE69735715D1 publication Critical patent/DE69735715D1/de
Application granted granted Critical
Publication of DE69735715T2 publication Critical patent/DE69735715T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69735715T 1996-05-01 1997-05-01 Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird Expired - Lifetime DE69735715T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1663296P 1996-05-01 1996-05-01
US64225096A 1996-05-01 1996-05-01
US642250 1996-05-01
US16632P 1996-05-01
PCT/US1997/007198 WO1997041151A2 (en) 1996-05-01 1997-05-01 Choline binding proteins for anti-pneumococcal vaccines

Publications (2)

Publication Number Publication Date
DE69735715D1 DE69735715D1 (de) 2006-05-24
DE69735715T2 true DE69735715T2 (de) 2007-03-29

Family

ID=26688869

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735715T Expired - Lifetime DE69735715T2 (de) 1996-05-01 1997-05-01 Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird

Country Status (8)

Country Link
EP (1) EP0912608B1 (enExample)
JP (1) JP2000511411A (enExample)
AT (1) ATE323721T1 (enExample)
AU (1) AU732520B2 (enExample)
CA (1) CA2253252A1 (enExample)
DE (1) DE69735715T2 (enExample)
ES (1) ES2262177T3 (enExample)
WO (1) WO1997041151A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078042B2 (en) 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
AU5355398A (en) 1996-11-12 1998-06-03 Regents Of The University Of Minnesota C3 binding protein of (streptococcus pneumoniae)
DE19708537A1 (de) * 1997-03-03 1998-09-10 Biotechnolog Forschung Gmbh Neues Oberflächenprotein (SpsA-Protein) von Streptococcus pneumoniae etc.
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
AU2004200125B2 (en) * 1998-04-07 2006-07-27 Med Immune, Inc. Derivatives of Pneumococcal Choline Binding Proteins for Vaccines
US6858706B2 (en) 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
DE69942176D1 (de) * 1998-04-07 2010-05-06 Medimmune Llc Choline-bindende proteine derivate aus pneumokoken als impfstoff
TR200003498T2 (tr) * 1998-04-07 2001-10-22 St. Jude Children's Research Hospital Amino asit sekansından oluşan bir polipetit, bunun aşıları ve kullanımları
US20010016200A1 (en) 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
AU2027400A (en) * 1998-11-19 2000-06-05 St. Jude Children's Research Hospital Identification and characterization of novel pneumococcal choline binding proteins, cbpg and cbpd, and diagnostic and therapeutic uses thereof
US6495139B2 (en) 1998-11-19 2002-12-17 St. Jude Children's Research Hospital Identification and characterization of novel pneumococcal choline binding protein, CBPG, and diagnostic and therapeutic uses thereof
CA2355364C (en) 1998-12-21 2014-03-18 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
MY125387A (en) 1999-03-19 2006-07-31 Smithkline Beecham Biologicals S A Vaccine
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
WO2004014417A2 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine compositions comprising l2 and/or l3 immunotype lipooligosaccharides from lgtb- neisseria minigitidis
CA2503946C (en) 2002-11-01 2016-08-16 Glaxosmithkline Biologicals S.A. Drying process
WO2005032584A2 (en) 2003-10-02 2005-04-14 Glaxosmithkline Biologicals S.A. Pertussis antigens and use thereof in vaccination
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
EA014107B1 (ru) 2005-12-22 2010-10-29 Глаксосмитклайн Байолоджикалс С.А. Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
EA015561B1 (ru) 2006-01-17 2011-08-30 Арне Форсгрен НОВЫЙ ПОВЕРХНОСТНЫЙ БЕЛОК HAEMOPHILUS INFLUENZAE (БЕЛОК E; pE)
BRPI0813644B8 (pt) 2007-06-26 2021-05-25 Glaxosmithkline Biologicals Sa composição imunogênica, vacina, processo para fabricar a mesma, e, uso da composição imunogênica ou vacina
CN102099052A (zh) 2008-04-16 2011-06-15 葛兰素史密丝克莱恩生物有限公司 疫苗
WO2010126146A1 (ja) * 2009-04-30 2010-11-04 Tanaka Noriaki 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
BR112012022669A2 (pt) 2010-03-10 2017-02-14 Glaxosmithkline Biologicals Sa composição imunogênica, método de tratamento ou prevenção de infecção ou doença, uso de um antígeno, kit, métodos para a fabricação de uma composição imunogênica e para melhorar uma vacina.
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
EP2709658A1 (en) 2011-05-17 2014-03-26 GlaxoSmithKline Biologicals SA Vaccine against streptococcus pneumoniae
US11207396B2 (en) 2013-05-17 2021-12-28 The Board Of Regents Of The University Of Texas System Immunization to protect against adverse cardiac events relating to pneumococcal infection
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CN115335504A (zh) * 2019-11-18 2022-11-11 Vaxcyte公司 链球菌的无动物产物培养

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4400293A (en) * 1992-05-29 1993-12-30 Janet Yother Methods for obtaining and purifying cell-free pneumococcal surface proteins from (s. pneumoniae) and use thereof
CA2116261A1 (en) * 1993-04-20 1994-10-21 David E. Briles Epitopic regions of pneumococcal surface protein a
JPH11507214A (ja) * 1995-06-07 1999-06-29 バイオケム ヴァシーンズ インク. Hsp70ファミリーに属する連鎖球菌の熱ショック蛋白質メンバー

Also Published As

Publication number Publication date
JP2000511411A (ja) 2000-09-05
ES2262177T3 (es) 2006-11-16
WO1997041151A2 (en) 1997-11-06
EP0912608B1 (en) 2006-04-19
CA2253252A1 (en) 1997-11-06
DE69735715D1 (de) 2006-05-24
ATE323721T1 (de) 2006-05-15
AU2818297A (en) 1997-11-19
EP0912608A2 (en) 1999-05-06
AU732520B2 (en) 2001-04-26

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