DE69733836T2 - Vorrichtung zur körperflüssigkeitsentnahme und -analyse - Google Patents

Vorrichtung zur körperflüssigkeitsentnahme und -analyse Download PDF

Info

Publication number
DE69733836T2
DE69733836T2 DE69733836T DE69733836T DE69733836T2 DE 69733836 T2 DE69733836 T2 DE 69733836T2 DE 69733836 T DE69733836 T DE 69733836T DE 69733836 T DE69733836 T DE 69733836T DE 69733836 T2 DE69733836 T2 DE 69733836T2
Authority
DE
Germany
Prior art keywords
body fluid
sampling device
test strip
housing
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69733836T
Other languages
German (de)
English (en)
Other versions
DE69733836D1 (de
Inventor
S. Joel DOUGLAS
N. Jeffrey ROE
Ryszard Radwanski
G. Brent DUCHON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Operations Inc
Original Assignee
Roche Diagnostics Operations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Operations Inc filed Critical Roche Diagnostics Operations Inc
Publication of DE69733836D1 publication Critical patent/DE69733836D1/de
Application granted granted Critical
Publication of DE69733836T2 publication Critical patent/DE69733836T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150068—Means for enhancing collection by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150083—Means for enhancing collection by vibration, e.g. ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106—Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced
    • A61B5/150137—Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced by vibration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106—Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced
    • A61B5/15016—Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced by accessories for bringing the piercing element into the body, e.g. through rotation of the piercing element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150175—Adjustment of penetration depth
    • A61B5/15019—Depth adjustment mechanism using movable stops located inside the piercing device housing and limiting the travel of the drive mechanism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150175—Adjustment of penetration depth
    • A61B5/150198—Depth adjustment mechanism at the proximal end of the carrier of the piercing element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150343—Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150396—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150419—Pointed piercing elements, e.g. needles, lancets for piercing the skin comprising means for capillary action
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150427—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150473—Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A61B5/150519—Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150801—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150824—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15111—Semi-automatically triggered, e.g. at the end of the cocking procedure, for instance by biasing the main drive spring or when reaching sufficient contact pressure, the piercing device is automatically triggered without any deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • A61B5/15136—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids by use of radiation, e.g. laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/15192—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
    • A61B5/15194—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nanotechnology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Composite Materials (AREA)
  • General Physics & Mathematics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Surgical Instruments (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Optical Measuring Cells (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
DE69733836T 1996-05-17 1997-05-16 Vorrichtung zur körperflüssigkeitsentnahme und -analyse Expired - Lifetime DE69733836T2 (de)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US1713396P 1996-05-17 1996-05-17
US17133P 1996-05-17
US1991896P 1996-06-14 1996-06-14
US19918P 1996-06-14
US2365896P 1996-08-01 1996-08-01
US23658P 1996-08-01
US2534096P 1996-09-03 1996-09-03
US25340P 1996-09-03
US71454896A 1996-09-16 1996-09-16
US714548 1996-09-16
US71045696A 1996-09-17 1996-09-17
US710456 1996-09-17
US72707496A 1996-10-08 1996-10-08
US727074 1996-10-08
PCT/US1997/008399 WO1997042882A1 (en) 1996-05-17 1997-05-16 Methods and apparatus for sampling and analyzing body fluid

Publications (2)

Publication Number Publication Date
DE69733836D1 DE69733836D1 (de) 2005-09-01
DE69733836T2 true DE69733836T2 (de) 2006-04-27

Family

ID=27567563

Family Applications (11)

Application Number Title Priority Date Filing Date
DE29723357U Expired - Lifetime DE29723357U1 (de) 1996-05-17 1997-05-16 Vorrichtung zur Entnahme von Körperflüssigkeitsproben
DE19758808A Expired - Lifetime DE19758808B4 (de) 1996-05-17 1997-05-16 Probenentnahmevorrichtung für Körperflüssigkeit
DE19781044T Expired - Lifetime DE19781044B4 (de) 1996-05-17 1997-05-16 Verfahren und Vorrichtungen zum Ausdrücken von Körperflüssigkeit aus einem Einstich
DE19758805A Expired - Lifetime DE19758805B4 (de) 1996-05-17 1997-05-16 Vorrichtung zur Entnahme von Körperflüssigkeitsproben und Verfahren zu ihrer Verwendung
DE19781046T Expired - Lifetime DE19781046B4 (de) 1996-05-17 1997-05-16 Vorrichtung zur Entnahme von Körperflüssigkeitsproben und Verfahren zu ihrer Herstellung
DE19781097T Expired - Lifetime DE19781097B4 (de) 1996-05-17 1997-05-16 Blut- und Körperfluidprobenentnahmevorrichtung sowie Verfahren zur Erlangung einer Körperfluidprobe
DE69738420T Expired - Lifetime DE69738420T2 (de) 1996-05-17 1997-05-16 Körperflüssigkeitsentnahmevorrichtung
DE29723371U Expired - Lifetime DE29723371U1 (de) 1996-05-17 1997-05-16 Vorrichtung zum Ausdrücken von Körperflüssigkeit aus einem Einstich
DE19758948A Expired - Lifetime DE19758948B3 (de) 1996-05-17 1997-05-16 Mehrkammerröhre zur Verwendung in einer Körperfluidprobenentnahmevorrichtung zum Sammeln einer Körperfluidprobe
DE19758959A Expired - Lifetime DE19758959B8 (de) 1996-05-17 1997-05-16 Vorrichtung zum Ausdrücken von Körperflüssigkeiten aus einem Einstich
DE69733836T Expired - Lifetime DE69733836T2 (de) 1996-05-17 1997-05-16 Vorrichtung zur körperflüssigkeitsentnahme und -analyse

Family Applications Before (10)

Application Number Title Priority Date Filing Date
DE29723357U Expired - Lifetime DE29723357U1 (de) 1996-05-17 1997-05-16 Vorrichtung zur Entnahme von Körperflüssigkeitsproben
DE19758808A Expired - Lifetime DE19758808B4 (de) 1996-05-17 1997-05-16 Probenentnahmevorrichtung für Körperflüssigkeit
DE19781044T Expired - Lifetime DE19781044B4 (de) 1996-05-17 1997-05-16 Verfahren und Vorrichtungen zum Ausdrücken von Körperflüssigkeit aus einem Einstich
DE19758805A Expired - Lifetime DE19758805B4 (de) 1996-05-17 1997-05-16 Vorrichtung zur Entnahme von Körperflüssigkeitsproben und Verfahren zu ihrer Verwendung
DE19781046T Expired - Lifetime DE19781046B4 (de) 1996-05-17 1997-05-16 Vorrichtung zur Entnahme von Körperflüssigkeitsproben und Verfahren zu ihrer Herstellung
DE19781097T Expired - Lifetime DE19781097B4 (de) 1996-05-17 1997-05-16 Blut- und Körperfluidprobenentnahmevorrichtung sowie Verfahren zur Erlangung einer Körperfluidprobe
DE69738420T Expired - Lifetime DE69738420T2 (de) 1996-05-17 1997-05-16 Körperflüssigkeitsentnahmevorrichtung
DE29723371U Expired - Lifetime DE29723371U1 (de) 1996-05-17 1997-05-16 Vorrichtung zum Ausdrücken von Körperflüssigkeit aus einem Einstich
DE19758948A Expired - Lifetime DE19758948B3 (de) 1996-05-17 1997-05-16 Mehrkammerröhre zur Verwendung in einer Körperfluidprobenentnahmevorrichtung zum Sammeln einer Körperfluidprobe
DE19758959A Expired - Lifetime DE19758959B8 (de) 1996-05-17 1997-05-16 Vorrichtung zum Ausdrücken von Körperflüssigkeiten aus einem Einstich

Country Status (11)

Country Link
EP (2) EP0955909B1 (enExample)
JP (2) JP3356782B2 (enExample)
AT (2) ATE381904T1 (enExample)
AU (6) AU3207197A (enExample)
DE (11) DE29723357U1 (enExample)
DK (3) DK64698A (enExample)
ES (2) ES2284185T3 (enExample)
GB (4) GB2322561B (enExample)
IL (3) IL124425A0 (enExample)
MX (2) MX9804093A (enExample)
WO (4) WO1997042885A1 (enExample)

Families Citing this family (227)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US7235056B2 (en) 1996-05-17 2007-06-26 Amira Medical Body fluid sampling device and methods of use
US7828749B2 (en) 1996-05-17 2010-11-09 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
US20020010406A1 (en) 1996-05-17 2002-01-24 Douglas Joel S. Methods and apparatus for expressing body fluid from an incision
EP1579814A3 (en) 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US5951493A (en) * 1997-05-16 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for expressing body fluid from an incision
US7666150B2 (en) * 1996-05-17 2010-02-23 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
US6071249A (en) * 1996-12-06 2000-06-06 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
EP0958495B1 (en) 1997-02-06 2002-11-13 Therasense, Inc. Small volume in vitro analyte sensor
US5948695A (en) * 1997-06-17 1999-09-07 Mercury Diagnostics, Inc. Device for determination of an analyte in a body fluid
US5964718A (en) 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
CA2312756C (en) * 1997-12-04 2006-07-18 Roche Diagnostics Corporation Instrument
GB2373731B (en) * 1997-12-04 2002-12-04 Agilent Technologies Inc Apparatus and method for sampling blood
US6071294A (en) * 1997-12-04 2000-06-06 Agilent Technologies, Inc. Lancet cartridge for sampling blood
US5871494A (en) * 1997-12-04 1999-02-16 Hewlett-Packard Company Reproducible lancing for sampling blood
US7390667B2 (en) 1997-12-22 2008-06-24 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC phase angle measurements
US7407811B2 (en) 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
US7494816B2 (en) 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
JP2000014662A (ja) * 1998-01-22 2000-01-18 Terumo Corp 体液検査装置
US6103033A (en) 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6086545A (en) * 1998-04-28 2000-07-11 Amira Medical Methods and apparatus for suctioning and pumping body fluid from an incision
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US7384396B2 (en) 1998-07-21 2008-06-10 Spectrx Inc. System and method for continuous analyte monitoring
US7037277B1 (en) 1998-07-21 2006-05-02 Spectrx, Inc. System and method for fluid management in a continuous fluid collection and sensor device
EP1098589B1 (en) * 1998-07-21 2006-02-22 SPECTRX, Inc. Continuous fluid collection and sensor device
JP2004510453A (ja) * 1998-07-21 2004-04-08 スペクトルクス，インコーポレイティド 連続状分析物監視用のシステムおよび方法
CA2346055C (en) 1998-09-30 2004-06-29 Cygnus, Inc. Method and device for predicting physiological values
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
CA2369336A1 (en) 1999-04-22 2000-11-02 Cygnus, Inc. Hydrogel in an iontophoretic device to measure glucose
EP2322645A1 (en) 1999-06-18 2011-05-18 Abbott Diabetes Care Inc. Mass transport limited in vivo analyte sensor
DE19946059A1 (de) * 1999-09-25 2001-03-29 Roche Diagnostics Gmbh System zur transdermalen Gewinnung von Körperflüssigkeit
US6283982B1 (en) 1999-10-19 2001-09-04 Facet Technologies, Inc. Lancing device and method of sample collection
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
EP1238632B1 (en) * 1999-12-13 2011-05-11 ARKRAY, Inc. Body fluid measuring apparatus with lancet and lancet holder used for the measuring apparatus
US6706159B2 (en) * 2000-03-02 2004-03-16 Diabetes Diagnostics Combined lancet and electrochemical analyte-testing apparatus
DE10010694A1 (de) 2000-03-04 2001-09-06 Roche Diagnostics Gmbh Blutlanzette mit hygienischen Spitzenschutz
US6885883B2 (en) 2000-05-16 2005-04-26 Cygnus, Inc. Methods for improving performance and reliability of biosensors
DE10026172A1 (de) 2000-05-26 2001-11-29 Roche Diagnostics Gmbh System zur Entnahme von Körperflüssigkeit
JP5180418B2 (ja) * 2000-06-01 2013-04-10 サイエンス アプリケーションズ インターナショナル コーポレイション 健康状態をモニタリングするため、および経皮にて薬剤を送達するためのシステムおよび方法
US6553244B2 (en) 2000-08-18 2003-04-22 Cygnus, Inc. Analyte monitoring device alarm augmentation system
WO2002015777A1 (en) 2000-08-18 2002-02-28 Cygnus, Inc. Methods and devices for prediction of hypoglycemic events
ATE298528T1 (de) * 2000-10-13 2005-07-15 Alza Corp Mikroklingeanordungsaufprallapplikator
DE10053974A1 (de) 2000-10-31 2002-05-29 Roche Diagnostics Gmbh System zur Blutentnahme
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
CZ20031992A3 (cs) 2001-01-22 2004-11-10 F. Hoffmann-La Roche Ag Lancetové zařízení s kapilární vzlínavostí
US7310543B2 (en) 2001-03-26 2007-12-18 Kumetrix, Inc. Silicon microprobe with integrated biosensor
US6752817B2 (en) * 2001-03-26 2004-06-22 Bayer Corporation Split pressure ring for lancing device and method of operation
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
WO2002100276A1 (en) * 2001-06-08 2002-12-19 Roche Diagnostics Gmbh Devices and methods for the expression of bodily fluids from an incision
US20020188223A1 (en) 2001-06-08 2002-12-12 Edward Perez Devices and methods for the expression of bodily fluids from an incision
CA2694412C (en) 2001-06-08 2018-06-19 F. Hoffmann-La Roche Ag Bodily fluid sampling device and test media cassette to be used with such a device
US6501976B1 (en) 2001-06-12 2002-12-31 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US6721586B2 (en) 2001-06-12 2004-04-13 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
WO2002100252A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Blood sampling apparatus and method
US6837988B2 (en) 2001-06-12 2005-01-04 Lifescan, Inc. Biological fluid sampling and analyte measurement devices and methods
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US6793632B2 (en) 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US6875613B2 (en) 2001-06-12 2005-04-05 Lifescan, Inc. Biological fluid constituent sampling and measurement devices and methods
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7537571B2 (en) 2001-06-12 2009-05-26 Pelikan Technologies, Inc. Integrated blood sampling analysis system with multi-use sampling module
AU2002315177A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
DE10134650B4 (de) * 2001-07-20 2009-12-03 Roche Diagnostics Gmbh System zur Entnahme kleiner Körperflüssigkeitsmengen
EP1854408B1 (en) * 2001-08-16 2010-10-27 Lifescan Scotland Ltd In-situ adapter for an analyte testing device
DE10142232B4 (de) 2001-08-29 2021-04-29 Roche Diabetes Care Gmbh Verfahren zur Herstellung eines analytischen Hilfsmittels mit Lanzette und Testelement
CA2458208A1 (en) 2001-08-29 2003-03-13 F. Hoffmann-La Roche Ag Wicking methods and structures for use in sampling bodily fluids
WO2003039369A1 (en) 2001-09-26 2003-05-15 Roche Diagnostics Gmbh Method and apparatus for sampling bodily fluid
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
US7357808B2 (en) 2002-01-31 2008-04-15 Facet Technologies, Llc Single use device for blood microsampling
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
DE10206254A1 (de) 2002-02-15 2003-08-28 Roche Diagnostics Gmbh System zur schmerzarmen Blutentnahme
ATE507766T1 (de) 2002-03-22 2011-05-15 Animas Technologies Llc Leistungsverbesserung einer analytenüberwachungsvorrichtung
CN1547452A (zh) * 2002-04-04 2004-11-17 ���µ�����ҵ��ʽ���� 小刀装置
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7244265B2 (en) 2002-04-19 2007-07-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7198606B2 (en) 2002-04-19 2007-04-03 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with analyte sensing
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
EP1501402A4 (en) 2002-04-19 2008-07-02 Pelikan Technologies Inc DEVICE AND METHOD FOR A LANZETTE AT VARIABLE SPEED
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7485128B2 (en) 2002-04-19 2009-02-03 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7060192B2 (en) 2002-05-09 2006-06-13 Lifescan, Inc. Methods of fabricating physiological sample collection devices
DE60317197T2 (de) 2002-05-31 2008-08-07 Facet Technologies, Llc Präzise geführte lanzette
NZ526334A (en) * 2002-06-25 2003-10-31 Bayer Healthcare Llc Sensor with integrated lancet for monitoring blood by colorometric or electrochemical test method
US7150975B2 (en) 2002-08-19 2006-12-19 Animas Technologies, Llc Hydrogel composition for measuring glucose flux
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
AU2003300540A1 (en) 2002-12-23 2004-07-14 F. Hoffmann-La Roche Ag Body fluid testing device
US7582258B2 (en) 2002-12-23 2009-09-01 Roche Diagnostics Operations, Inc. Body fluid testing device
US20040122339A1 (en) 2002-12-24 2004-06-24 Roe Steven N. Sampling devices and methods utilizing biased capillary action
DE60329712D1 (de) * 2002-12-30 2009-11-26 Hoffmann La Roche Blutaquisitionssuspensionssystem
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
EP1578262A4 (en) 2002-12-31 2007-12-05 Therasense Inc CONTINUOUS BLOOD SUGAR MONITORING SYSTEM AND USE METHOD
US7228162B2 (en) 2003-01-13 2007-06-05 Isense Corporation Analyte sensor
DE10315544B4 (de) 2003-04-04 2007-02-15 Roche Diagnostics Gmbh Verfahren zur Herstellung einer Stech- und Mess-Vorrichtung sowie Vorrichtung
EP1638454B1 (en) * 2003-05-30 2016-06-22 Sanofi-Aventis Deutschland GmbH Apparatus for body fluid sampling and analyte sensing
DE10325699B3 (de) 2003-06-06 2005-02-10 Roche Diagnostics Gmbh System zur Analyse einer zu untersuchenden Probe und Verwendung eines solchen Systems
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1635700B1 (en) 2003-06-13 2016-03-09 Sanofi-Aventis Deutschland GmbH Apparatus for a point of care device
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US7645421B2 (en) 2003-06-20 2010-01-12 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7718439B2 (en) 2003-06-20 2010-05-18 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7604721B2 (en) 2003-06-20 2009-10-20 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
EP1680154B1 (en) 2003-10-31 2012-01-04 ALZA Corporation Self-actuating applicator for microprojection array
US20050096686A1 (en) * 2003-10-31 2005-05-05 Allen John J. Lancing device with trigger mechanism for penetration depth control
USD914881S1 (en) 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
CA2553632A1 (en) 2004-02-06 2005-08-25 Bayer Healthcare Llc Oxidizable species as an internal reference for biosensors and method of use
CA2556331A1 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
US7819822B2 (en) 2004-03-06 2010-10-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
PT2705792E (pt) 2004-03-06 2015-07-07 Hoffmann La Roche Dispositivo de amostragem de fluido corporal
US7452366B2 (en) 2004-05-06 2008-11-18 Eumed Biotechnology Co., Ltd. Safety lancet device
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
US20060036187A1 (en) * 2004-06-30 2006-02-16 Hester Vos Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein
US7727166B2 (en) 2004-07-26 2010-06-01 Nova Biomedical Corporation Lancet, lancet assembly and lancet-sensor combination
WO2006063063A2 (en) 2004-12-09 2006-06-15 Flexible Medical Systems, Llc Apparatus and method for continuous real-time trace biomolecular sampling, analysis and delivery
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
DE102005003789A1 (de) 2005-01-19 2006-07-27 Roche Diagnostics Gmbh Testeinheit für Einmaluntersuchungen einer Körperflüssigkeit
JPWO2006109452A1 (ja) 2005-03-31 2008-10-16 テルモ株式会社 穿刺装置
EP1716808A1 (en) * 2005-04-29 2006-11-02 Eumed Biotechnology Co., Ltd. Safety lancet device
US8425432B2 (en) 2005-05-05 2013-04-23 Bayer Healthcare Llc Reconfigurable integrated lancet system
EP1913374B1 (en) 2005-07-20 2019-01-09 Ascensia Diabetes Care Holdings AG Method for signalling the user to add additional sample to a test strip, method for measuring the temperature of a sample and methods for determining the concentration of an analyte based on gated amperometry
JP5232003B2 (ja) 2005-09-30 2013-07-10 インテュイティ メディカル インコーポレイテッド 多部分体液試料採取及び分析カートリッジ
EP3483598B1 (en) 2005-09-30 2024-11-06 Ascensia Diabetes Care Holdings AG Gated voltammetry
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
JP5420246B2 (ja) 2005-10-15 2014-02-19 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 体液の検査をするためのテストエレメントおよびテストシステム
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US8333874B2 (en) 2005-12-09 2012-12-18 Flexible Medical Systems, Llc Flexible apparatus and method for monitoring and delivery
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8052618B2 (en) 2006-10-15 2011-11-08 Roche Diagnostics Operations, Inc. Diagnostic test element and process for its production
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
US7766846B2 (en) 2008-01-28 2010-08-03 Roche Diagnostics Operations, Inc. Rapid blood expression and sampling
AU2013202929B2 (en) * 2008-01-28 2016-05-26 F. Hoffmann-La Roche Ag System for detection of an analyte in a body fluid
EP2265324B1 (en) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integrated analyte measurement system
CN101896121B (zh) * 2008-05-09 2012-02-29 松下电器产业株式会社 皮肤切开器具以及使用该皮肤切开器具切开皮肤的方法
CN101938941B (zh) 2008-05-13 2012-07-25 松下电器产业株式会社 皮肤切开器具
WO2009145920A1 (en) 2008-05-30 2009-12-03 Intuity Medical, Inc. Body fluid sampling device -- sampling site interface
EP3984454A1 (en) 2008-06-06 2022-04-20 Intuity Medical, Inc. Medical diagnostic devices and methods
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
US8758267B2 (en) 2009-03-17 2014-06-24 Nova Biomedical Corporation Modified lancet carrier for single-use lancet sensor assembly
WO2010127050A1 (en) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
EP2506768B1 (en) 2009-11-30 2016-07-06 Intuity Medical, Inc. Calibration material delivery devices and methods
USD634426S1 (en) 2010-04-08 2011-03-15 Facet Technologies, Llc Lancing device
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP2584964B1 (en) 2010-06-25 2021-08-04 Intuity Medical, Inc. Analyte monitoring devices
CA2809578C (en) 2010-08-26 2017-03-21 James Hill Biological fluid sampling and storage apparatus for remote use
US9451913B2 (en) 2010-12-10 2016-09-27 Touchtek Labs, Llc Transdermal sampling and analysis device
US9877673B2 (en) 2010-12-10 2018-01-30 Clinitech, Llc Transdermal sampling and analysis device
EP4062831B1 (en) 2011-08-03 2023-11-08 Intuity Medical, Inc. Body fluid sampling arrangement
JP6443802B2 (ja) 2011-11-07 2018-12-26 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 分析物モニタリング装置および方法
US9968284B2 (en) 2011-12-02 2018-05-15 Clinitech, Llc Anti-interferent barrier layers for non-invasive transdermal sampling and analysis device
LT4056105T (lt) 2011-12-11 2024-01-10 Abbott Diabetes Care, Inc. Analitės jutiklių įrenginiai
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US10004434B1 (en) 2013-03-15 2018-06-26 Georgetown University Microfluidic systems for electrochemical transdermal analyte sensing using a capillary-located electrode
US10898116B2 (en) 2013-03-15 2021-01-26 Cambridge Medical Technologies LLC Methods of manufacture to optimize performance of transdermal sampling and analysis device
JP5682654B2 (ja) * 2013-05-07 2015-03-11 セイコーエプソン株式会社 流体噴射装置及び手術器具
CA2911449C (en) * 2013-05-15 2019-02-26 Becton, Dickinson And Company Manual flow regulation for blood collection
CA2912283A1 (en) 2013-06-21 2014-12-21 Intuity Medical, Inc. Analyte monitoring system with audible feedback
CN107072605B (zh) * 2014-05-21 2020-07-21 广州市健之堂医疗器械有限公司 一种弹卸式采血笔结构
US9730625B2 (en) * 2015-03-02 2017-08-15 Verily Life Sciences Llc Automated blood sampling device
WO2017023931A1 (en) 2015-08-03 2017-02-09 Georgetown University Apparatus and method for delivery of antimicrobial during a transdermal sampling and delivery process
AU2016306713C1 (en) * 2015-08-12 2023-06-01 University Of Tasmania Liquid collection device
US9629991B1 (en) 2016-06-08 2017-04-25 Eclipse Aesthetics, LLC Disposable radio frequency needle cartridges having absorbing containment barriers
US9636491B1 (en) 2016-06-08 2017-05-02 Eclipse Aesthetics, LLC Disposable needle cartridges having absorbing contaminant barriers
US10220195B2 (en) 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
CN106324235B (zh) * 2016-08-12 2018-07-13 上海移宇科技股份有限公司 一步式全集成体液采样分析笔
EP3570735A4 (en) 2017-01-23 2020-10-21 Abbott Diabetes Care Inc. SYSTEMS, DEVICES AND METHODS FOR INSERTING ANALYTE SENSOR
US11696711B2 (en) 2017-07-06 2023-07-11 Becton, Dickinson And Company Biological fluid collection device
WO2019188907A1 (ja) * 2018-03-29 2019-10-03 富士フイルム株式会社 採血用ランセット及び血液検査キット
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
CN109998568A (zh) * 2019-04-28 2019-07-12 殷盈祥 一种检验科无痛式自助采血装置
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
AU2021333904A1 (en) 2020-08-31 2023-03-02 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor insertion
CN114224392B (zh) * 2021-11-23 2024-06-18 深圳市罗湖医院集团 采样器及采样设备
CN118530826B (zh) * 2024-06-20 2024-12-13 宁波市甬环苑环保工程科技有限公司 一种水生生物eDNA样品自动采集装置及方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3030959A (en) * 1959-09-04 1962-04-24 Praemeta Surgical lancet for blood sampling
CH500707A (fr) * 1968-07-26 1970-12-31 Micromedic Systems Inc Dispositif pour effectuer une prise de sang percutanée et digitale
CH538277A (fr) * 1970-09-04 1973-06-30 Micromedic Systems Inc Dispositif pour prise de sang percutanée
FR2371202A1 (fr) * 1976-11-23 1978-06-16 Anvar Dispositif d'aspiration automatique de liquide tel que sang
DE2751503C2 (de) * 1977-11-18 1983-03-24 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht Blutsammelgefäß
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4503856A (en) * 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4517978A (en) * 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
DK150403C (da) * 1983-07-15 1987-07-13 Radiometer As Blodproevetagningsudstyr
DE3426090A1 (de) * 1983-10-06 1985-04-18 Karl Storz GmbH & Co, 7200 Tuttlingen Geburtshilfeeinrichtung
EP0166574A3 (en) * 1984-06-28 1987-06-16 Mitchell P. Dombrowski, M.D. Fetal blood sampling instrument
US4787398A (en) * 1985-04-08 1988-11-29 Garid, Inc. Glucose medical monitoring system
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US5279294A (en) * 1985-04-08 1994-01-18 Cascade Medical, Inc. Medical diagnostic system
JPS61286738A (ja) * 1985-06-14 1986-12-17 オ−デイオバイオニクス　インコ−ポレイテツド 医療用システム
US4654513A (en) * 1985-07-31 1987-03-31 Hennessy Products, Inc. Newspaper vending machine
US4653513A (en) * 1985-08-09 1987-03-31 Dombrowski Mitchell P Blood sampler
DE3708031A1 (de) * 1986-03-20 1987-11-12 Wolfgang Dr Med Wagner Messeinrichtung oder induktionseinrichtung mit messeinrichtung oder vorrichtung zur materialgewinnung fuer eine messvorrichtung fuer stoffwechselzustaende im blut mittels punktion unter anwendung von unterdruck innerhalb einer saugglocke bei verlagerung der messzone ausserhalb des spitzenbereiches des punktionsgeraetes
US5029583A (en) * 1986-07-22 1991-07-09 Personal Diagnostics, Inc. Optical analyzer
US4806965A (en) * 1986-10-21 1989-02-21 Konica Corporation Apparatus for writing data onto photosensitive film
GB8710470D0 (en) * 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4858607A (en) * 1987-10-16 1989-08-22 Pavel Jordan & Associates Plastic device for injection and obtaining blood samples
US4844095A (en) * 1987-12-14 1989-07-04 Medicore, Inc. Automatic lancet device
US4924879A (en) * 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4920977A (en) * 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
US4895147A (en) * 1988-10-28 1990-01-23 Sherwood Medical Company Lancet injector
US4994073A (en) * 1989-02-22 1991-02-19 United States Surgical Corp. Skin fastener
US5054499A (en) * 1989-03-27 1991-10-08 Swierczek Remi D Disposable skin perforator and blood testing device
US4976724A (en) * 1989-08-25 1990-12-11 Lifescan, Inc. Lancet ejector mechanism
US5402798A (en) * 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
US5360047A (en) * 1991-11-08 1994-11-01 Sumitomo Rubber Industries, Ltd. Heavy duty radial tire with specified belt radius
ATE179876T1 (de) * 1991-11-12 1999-05-15 Urs A Ramel Lanzetteneinrichtung
JP2572823Y2 (ja) * 1992-02-13 1998-05-25 株式会社アドバンス 簡易採血器
US5165418B1 (en) * 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
DE4212315A1 (de) * 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
US5217480A (en) * 1992-06-09 1993-06-08 Habley Medical Technology Corporation Capillary blood drawing device
US5421816A (en) * 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5282822A (en) * 1993-01-19 1994-02-01 Sherwood Medical Company Lancet ejector for lancet injector
JP2630197B2 (ja) * 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
JPH0739542A (ja) * 1993-07-30 1995-02-10 Shibuya Kogyo Co Ltd 採血装置
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
HU219921B (hu) * 1993-10-20 2001-09-28 Ervin Lipscher Vérvételi eszköz, különösen ujjbegyből történő vérvételre
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5445611A (en) * 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
GB9422260D0 (en) * 1994-11-04 1994-12-21 Owen Mumford Ltd Improvements relating to skin prickers
US5512158A (en) * 1995-02-28 1996-04-30 Hewlett-Packard Company Capillary electrophoresis method and apparatus for electric field uniformity and minimal dispersion of sample fractions
DE29514084U1 (de) * 1995-09-01 1995-11-02 Biosafe Diagnostics Corp., Lincolnshire, Ill. Blutentnahme- und -testvorrichtung
DE19604156A1 (de) * 1996-02-06 1997-08-07 Boehringer Mannheim Gmbh Schneidvorrichtung für Haut zur schmerzarmen Entnahme kleiner Blutmengen

Also Published As

Publication number Publication date
ATE381904T1 (de) 2008-01-15
WO1997042882A1 (en) 1997-11-20
DK64798A (da) 1999-01-18
AU3368297A (en) 1997-12-05
DE19758948B3 (de) 2013-11-14
GB2323792B (en) 2000-05-10
DE19758959B4 (de) 2013-07-18
DE19781046B4 (de) 2005-06-23
AU3131097A (en) 1997-12-05
EP0955909B1 (en) 2005-07-27
DE69733836D1 (de) 2005-09-01
DK64698A (da) 1999-01-18
JP2002502271A (ja) 2002-01-22
IL124510A0 (en) 1998-12-06
EP0904022A4 (en) 1999-12-29
DK67498A (da) 1999-01-18
EP0955909A4 (en) 1999-12-29
GB2323792A (en) 1998-10-07
ES2121564T6 (es) 1998-11-16
WO1997042886A1 (en) 1997-11-20
DE19781097B4 (de) 2006-07-20
EP0904022A1 (en) 1999-03-31
JP3356782B2 (ja) 2002-12-16
DE29723371U1 (de) 1998-08-06
DE19781044B4 (de) 2005-11-17
GB9810082D0 (en) 1998-07-08
DE19758805B4 (de) 2009-10-15
GB2322561A (en) 1998-09-02
AU3284797A (en) 1997-12-05
GB9810081D0 (en) 1998-07-08
ES2284185T3 (es) 2007-11-01
GB2322562A (en) 1998-09-02
AU3206797A (en) 1997-12-09
DE19781044T1 (de) 1998-12-03
GB2322562B (en) 2001-03-28
GB2322561B (en) 2000-08-16
IL124426A (en) 2000-06-01
MX9804157A (es) 1998-09-30
WO1997042885A1 (en) 1997-11-20
ATE300236T1 (de) 2005-08-15
EP0955909A1 (en) 1999-11-17
GB2325167B (en) 2000-05-10
DE69738420D1 (de) 2008-02-07
GB2325167A (en) 1998-11-18
AU3207197A (en) 1997-12-05
GB9811004D0 (en) 1998-07-22
JP2002503118A (ja) 2002-01-29
DE19758808B4 (de) 2009-11-26
IL124425A0 (en) 1998-12-06
DE69738420T2 (de) 2008-05-21
MX9804093A (es) 1998-09-30
DE19758959B8 (de) 2013-08-01
DE19781097T1 (de) 1999-07-01
JP3802568B2 (ja) 2006-07-26
AU3070397A (en) 1997-12-05
GB9811003D0 (en) 1998-07-22
GB2322562A8 (en) 1998-09-03
EP0904022B1 (en) 2007-04-04
DE19781046T1 (de) 1998-12-24
IL124426A0 (en) 1998-12-06
DE29723357U1 (de) 1998-10-15
WO1997042888A1 (en) 1997-11-20

Similar Documents

Publication Publication Date Title
DE69733836T2 (de) Vorrichtung zur körperflüssigkeitsentnahme und -analyse
DE10134650B4 (de) System zur Entnahme kleiner Körperflüssigkeitsmengen
EP1287785B1 (de) Analytisches Hilfsmittel mit Lanzette und Testelement
DE60303987T2 (de) Flüssigkeitssensor mit integrierter Lanzette
EP1289422B1 (de) System zur entnahme von körperflüssigkeit, insbesondere blut
DE60124181T2 (de) Mikrohohlnadelpflaster
DE19781098B4 (de) Einwegelement, Einweglanzettenelement und Kapillarelement zur Verwendung in einer Probenentnahmevorrichtung für Körperflüssigkeit
DE19855458C2 (de) Lanzettenkassette zur Blutprobennahme
DE69733486T2 (de) Vorrichtung zur blutgewinnung für diagnostische tests
EP1868491B1 (de) Analytisches hilfsmittel mit lanzette und testelement
DE60116281T2 (de) Verfahren und gerät zur probenentnahme und analyse von interstitieller flüssigkeit und vollblut
DE60221347T3 (de) In-situ adapter für ein analyten-testgerät
DE60018796T2 (de) Vorrichtung zur erhöhung des transdermalen flusses von probenwirkstoffen
EP2129289B1 (de) Analysesystem zur bestimmung eines analyten in einer körperflüssigkeit und disposibles integriertes probengewinnungs- und analyseelement
DE29809758U1 (de) Vorrichtung zur Entnahme von Körperflüssigkeitsproben
DE19855443A1 (de) Reproduzierbares Stechen zur Blutprobennahme
DE60215645T2 (de) Vorrichtungen zum ausdrücken von körperflüssigkeiten aus einem einschnitt
EP1776925A1 (de) Analytisches Hilfsmittel mit einer Lanzette und einer Testkammer
DE69737553T2 (de) Vorrichtung zur Probenentnahme von Körperflüssigkeit
DE19758804B4 (de) Mehrkammerröhre zur Verwendung in einer Körperfluidprobenentnahmevorrichtung und Verfahren zum Sammeln einer Körperfluidprobe
EP1894526A1 (de) Lanzette
DE19758806B4 (de) Vorrichtungen zum Ausdrücken von Körperflüssigkeit aus einem Einstich
DE20009476U1 (de) System zur Entnahme von Körperflüssigkeit

Legal Events

Date Code Title Description
8364 No opposition during term of opposition