DE69730314T2 - Dosierungsform von ibuprofen - Google Patents

Dosierungsform von ibuprofen Download PDF

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Publication number
DE69730314T2
DE69730314T2 DE69730314T DE69730314T DE69730314T2 DE 69730314 T2 DE69730314 T2 DE 69730314T2 DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T2 DE69730314 T2 DE 69730314T2
Authority
DE
Germany
Prior art keywords
dosage form
ibuprofen
weight
bicarbonate
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69730314T
Other languages
German (de)
English (en)
Other versions
DE69730314D1 (de
Inventor
Ashley Ian PRICE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of DE69730314D1 publication Critical patent/DE69730314D1/de
Publication of DE69730314T2 publication Critical patent/DE69730314T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69730314T 1996-02-21 1997-02-19 Dosierungsform von ibuprofen Expired - Lifetime DE69730314T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9603699.1A GB9603699D0 (en) 1996-02-21 1996-02-21 Therapeutic composition
GB9603699 1996-02-21
PCT/EP1997/000841 WO1997030699A2 (en) 1996-02-21 1997-02-19 Dosage form of ibuprofen

Publications (2)

Publication Number Publication Date
DE69730314D1 DE69730314D1 (de) 2004-09-23
DE69730314T2 true DE69730314T2 (de) 2005-08-18

Family

ID=10789176

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69730314T Expired - Lifetime DE69730314T2 (de) 1996-02-21 1997-02-19 Dosierungsform von ibuprofen

Country Status (25)

Country Link
US (1) US20020034540A1 (enrdf_load_stackoverflow)
EP (1) EP0881899B1 (enrdf_load_stackoverflow)
JP (2) JP2000507922A (enrdf_load_stackoverflow)
KR (1) KR19990087084A (enrdf_load_stackoverflow)
CN (1) CN1215989A (enrdf_load_stackoverflow)
AT (1) ATE273696T1 (enrdf_load_stackoverflow)
AU (1) AU722991B2 (enrdf_load_stackoverflow)
BG (1) BG64165B1 (enrdf_load_stackoverflow)
CA (1) CA2246344C (enrdf_load_stackoverflow)
CZ (1) CZ298371B6 (enrdf_load_stackoverflow)
DE (1) DE69730314T2 (enrdf_load_stackoverflow)
DK (1) DK0881899T3 (enrdf_load_stackoverflow)
ES (1) ES2227670T3 (enrdf_load_stackoverflow)
GB (1) GB9603699D0 (enrdf_load_stackoverflow)
HU (1) HUP9901454A3 (enrdf_load_stackoverflow)
IL (1) IL125803A0 (enrdf_load_stackoverflow)
NO (1) NO983825L (enrdf_load_stackoverflow)
NZ (1) NZ331416A (enrdf_load_stackoverflow)
PL (1) PL187383B1 (enrdf_load_stackoverflow)
PT (1) PT881899E (enrdf_load_stackoverflow)
RU (1) RU2182000C2 (enrdf_load_stackoverflow)
SK (1) SK285032B6 (enrdf_load_stackoverflow)
UA (1) UA55407C2 (enrdf_load_stackoverflow)
WO (1) WO1997030699A2 (enrdf_load_stackoverflow)
ZA (1) ZA971446B (enrdf_load_stackoverflow)

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IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US20030026835A1 (en) * 1999-02-15 2003-02-06 Sumitomo Pharmaceuticals Company Limited Tablets disintegrating rapidly in the oral cavity
US6368618B1 (en) 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
NZ508292A (en) * 1999-11-24 2002-08-28 Mcneil Ppc Inc Treatment of migraine symptoms with ibuprofen and salts thereof
KR100523242B1 (ko) * 2000-05-18 2005-10-24 한미약품 주식회사 이부프로펜을 함유하는 정제 조성물
US20020192161A1 (en) * 2001-04-10 2002-12-19 Fahkreddin Jamali Animal model for evaluating analgesics
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
CA2510320C (en) * 2002-12-20 2012-10-09 St. James Associates Llc/Faber Research Series Coated particles for sustained-release pharmaceutical administration
US20040176234A1 (en) * 2003-03-07 2004-09-09 Baker Hughes Incorporated Method for improving separation operation of centrifuges and associated improved separation designs
US20080020042A1 (en) * 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
PE20050445A1 (es) * 2003-10-30 2005-06-18 Bayer Consumer Care Ag Forma de presentacion del naproxeno sodico
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
ES2624585T3 (es) * 2004-05-28 2017-07-17 Imaginot Pty Ltd. Sistema de suministro de compuesto terapéutico oral
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
CN101513391B (zh) * 2004-06-29 2013-03-13 奈科明丹麦股份有限公司 水不溶性药快速释放药物组合物的制造方法及通过本方法得到的药物组合物
MX2007001689A (es) * 2004-08-12 2007-06-11 Reckitt Benckiser Healthcare Granulos que comprenden un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion en fase fundida.
US20070077297A1 (en) * 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
CN101068532B (zh) * 2004-09-30 2012-03-14 斯科尔医药公司 布洛芬改进释放剂型
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
EP1817021A1 (en) * 2004-11-03 2007-08-15 Equitech Corporation Nsaid compositions exhibiting clinical superiority
US20060177501A1 (en) * 2005-02-09 2006-08-10 Boehringer Ingelheim International Gmbh Film Coated Tablets Containing Ibuprofen
BRPI0609448A2 (pt) 2005-03-22 2010-04-06 Losan Pharma Gmbh ibuprofeno solubilizado
EP1800667A1 (en) 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
JP2009508951A (ja) * 2005-09-19 2009-03-05 アルベマール・コーポレーシヨン カリウムイブプロフェンの極めて濃厚な注入可能な水溶液、その製造法および使用
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
AU2006317530B2 (en) 2005-11-28 2011-09-01 Imaginot Pty Ltd Oral therapeutic compound delivery system
KR101288924B1 (ko) * 2006-08-16 2013-07-24 에스에스 세야쿠 가부시키 가이샤 경구투여용 제제
FI20070521A7 (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US8951562B2 (en) 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
WO2008079245A2 (en) * 2006-12-20 2008-07-03 Duramed Pharmaceuticals, Inc. Orally disintegrating solid dosage forms comprising progestin and methods of making and use thereof
CA2723409C (en) * 2008-05-09 2016-11-08 Atacama Labs Oy Method and apparatus for dry granulation
CA2730005C (en) * 2008-07-21 2017-06-13 Albermarle Corporation High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) * 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US20110144207A1 (en) * 2008-08-14 2011-06-16 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
SG176221A1 (en) * 2009-06-22 2012-01-30 Wyeth Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
JP5974469B2 (ja) * 2010-12-24 2016-08-23 ライオン株式会社 錠剤の製造方法
CN103102259B (zh) * 2011-12-23 2014-02-26 海南正瑞医药科技开发有限公司 一种布洛芬水合物晶体、及含该水合物晶体的药物组合物及其制备方法
WO2015016256A1 (ja) * 2013-07-30 2015-02-05 ライオン株式会社 錠剤
EP2845850A1 (en) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP2886107A1 (en) 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
CN114105850A (zh) 2014-07-02 2022-03-01 奥布赛瓦股份公司 治疗ot-r活性相关的病症的方法中可用的晶体
EP2965746B1 (en) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate
WO2017060920A1 (en) * 2015-10-05 2017-04-13 Strides Shasun Limited Pharmaceutical compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
US4684666A (en) * 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
WO1988003021A2 (en) * 1986-10-22 1988-05-05 The Upjohn Company Treatment of gingivitis with ibuprofen or flurbiprofen
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
DK0584108T3 (da) * 1991-05-13 2000-10-09 Boots Co Plc Farmaceutisk præparat omfattende ibuprofensalt
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
DK0607467T3 (da) * 1992-12-01 1999-12-13 Spirig Ag Lægemidler, der indeholder S(+)-ibuprofen

Also Published As

Publication number Publication date
BG64165B1 (bg) 2004-03-31
ES2227670T3 (es) 2005-04-01
AU1793797A (en) 1997-09-10
GB9603699D0 (en) 1996-04-17
KR19990087084A (ko) 1999-12-15
IL125803A0 (en) 1999-04-11
JP2000507922A (ja) 2000-06-27
SK285032B6 (sk) 2006-05-04
PL187383B1 (pl) 2004-06-30
HUP9901454A3 (en) 2001-04-28
CA2246344C (en) 2009-01-20
RU2182000C2 (ru) 2002-05-10
CZ298371B6 (cs) 2007-09-12
EP0881899B1 (en) 2004-08-18
PT881899E (pt) 2004-12-31
AU722991B2 (en) 2000-08-17
WO1997030699A3 (en) 1997-10-09
EP0881899A2 (en) 1998-12-09
JP2009073847A (ja) 2009-04-09
DK0881899T3 (da) 2004-12-20
BG102744A (bg) 1999-05-31
CN1215989A (zh) 1999-05-05
NZ331416A (en) 2000-02-28
DE69730314D1 (de) 2004-09-23
CZ261798A3 (cs) 1998-11-11
UA55407C2 (uk) 2003-04-15
HUP9901454A2 (hu) 1999-08-30
WO1997030699A2 (en) 1997-08-28
ZA971446B (en) 1997-11-25
ATE273696T1 (de) 2004-09-15
CA2246344A1 (en) 1997-08-28
US20020034540A1 (en) 2002-03-21
PL328465A1 (en) 1999-02-01
NO983825L (no) 1998-10-20
NO983825D0 (no) 1998-08-20
SK114298A3 (en) 1999-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE INTERNATIONAL LTD, GB

8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, GB