DE69724451T2 - Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen - Google Patents

Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen Download PDF

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Publication number
DE69724451T2
DE69724451T2 DE69724451T DE69724451T DE69724451T2 DE 69724451 T2 DE69724451 T2 DE 69724451T2 DE 69724451 T DE69724451 T DE 69724451T DE 69724451 T DE69724451 T DE 69724451T DE 69724451 T2 DE69724451 T2 DE 69724451T2
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DE
Germany
Prior art keywords
amino acid
binding protein
seq
tnf
tnf binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69724451T
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German (de)
English (en)
Other versions
DE69724451D1 (de
Inventor
M. Alison BENDELE
M. Regina SENNELLO
K. Carl EDWARDS
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Amgen Inc
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Amgen Inc
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Publication of DE69724451D1 publication Critical patent/DE69724451D1/de
Publication of DE69724451T2 publication Critical patent/DE69724451T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69724451T 1996-12-06 1997-12-08 Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen Expired - Lifetime DE69724451T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US3258796P 1996-12-06 1996-12-06
US32587P 1996-12-06
US3635597P 1997-01-23 1997-01-23
US36355P 1997-01-23
US3931597P 1997-02-07 1997-02-07
US39315P 1997-02-07
US5202397P 1997-07-09 1997-07-09
US52023P 1997-07-09
PCT/US1997/022733 WO1998024463A2 (en) 1996-12-06 1997-12-08 Combination therapy using a tnf binding protein for treating tnf-mediated diseases

Publications (2)

Publication Number Publication Date
DE69724451D1 DE69724451D1 (de) 2003-10-02
DE69724451T2 true DE69724451T2 (de) 2004-03-18

Family

ID=27488013

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69724451T Expired - Lifetime DE69724451T2 (de) 1996-12-06 1997-12-08 Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen

Country Status (11)

Country Link
US (4) US6306820B1 (enExample)
EP (1) EP0942740B1 (enExample)
JP (1) JP2001513754A (enExample)
AT (1) ATE247974T1 (enExample)
AU (1) AU5696198A (enExample)
CA (1) CA2273850A1 (enExample)
DE (1) DE69724451T2 (enExample)
DK (1) DK0942740T3 (enExample)
ES (1) ES2207759T3 (enExample)
PT (1) PT942740E (enExample)
WO (1) WO1998024463A2 (enExample)

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Also Published As

Publication number Publication date
AU5696198A (en) 1998-06-29
ES2207759T3 (es) 2004-06-01
EP0942740A2 (en) 1999-09-22
HK1022440A1 (en) 2000-08-11
US20040047863A1 (en) 2004-03-11
WO1998024463A2 (en) 1998-06-11
CA2273850A1 (en) 1998-06-11
EP0942740B1 (en) 2003-08-27
US20020119924A1 (en) 2002-08-29
US6306820B1 (en) 2001-10-23
ATE247974T1 (de) 2003-09-15
DK0942740T3 (da) 2003-12-15
US20040048799A1 (en) 2004-03-11
DE69724451D1 (de) 2003-10-02
PT942740E (pt) 2004-01-30
WO1998024463A3 (en) 1998-07-16
JP2001513754A (ja) 2001-09-04

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