DE69702775T2 - Chinolinonderivate und diese enthaltende antiallergische Zusammensetzungen - Google Patents

Chinolinonderivate und diese enthaltende antiallergische Zusammensetzungen

Info

Publication number
DE69702775T2
DE69702775T2 DE69702775T DE69702775T DE69702775T2 DE 69702775 T2 DE69702775 T2 DE 69702775T2 DE 69702775 T DE69702775 T DE 69702775T DE 69702775 T DE69702775 T DE 69702775T DE 69702775 T2 DE69702775 T2 DE 69702775T2
Authority
DE
Germany
Prior art keywords
group
quinolinone
hydroxy
methyl
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69702775T
Other languages
German (de)
English (en)
Other versions
DE69702775D1 (de
Inventor
Masayoshi Abe
Yasuo Aoki
Nobuyuki Kimura
Akihide Koda
Shigenori Nakanishi
Mitsuru Sakai
Hidetsugu Takagaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mariposa Health Ltd Bilgola Plateau New Sou Au
Original Assignee
Dainippon Ink and Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Ink and Chemicals Co Ltd filed Critical Dainippon Ink and Chemicals Co Ltd
Application granted granted Critical
Publication of DE69702775D1 publication Critical patent/DE69702775D1/de
Publication of DE69702775T2 publication Critical patent/DE69702775T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
DE69702775T 1996-01-17 1997-01-15 Chinolinonderivate und diese enthaltende antiallergische Zusammensetzungen Expired - Lifetime DE69702775T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP544996 1996-01-17
JP8270866A JP2943725B2 (ja) 1996-01-17 1996-10-14 キノリノン誘導体及びそれを有効成分とする抗アレルギー剤

Publications (2)

Publication Number Publication Date
DE69702775D1 DE69702775D1 (de) 2000-09-21
DE69702775T2 true DE69702775T2 (de) 2000-12-14

Family

ID=26339397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69702775T Expired - Lifetime DE69702775T2 (de) 1996-01-17 1997-01-15 Chinolinonderivate und diese enthaltende antiallergische Zusammensetzungen

Country Status (10)

Country Link
US (2) US5942521A (enExample)
EP (1) EP0785190B1 (enExample)
JP (1) JP2943725B2 (enExample)
KR (1) KR100210879B1 (enExample)
CN (2) CN1095834C (enExample)
AT (1) ATE195517T1 (enExample)
AU (1) AU685034B2 (enExample)
CA (1) CA2195031C (enExample)
DE (1) DE69702775T2 (enExample)
TW (1) TW445258B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW430656B (en) * 1997-12-03 2001-04-21 Dainippon Ink & Chemicals Quinolinone derivative, method for preparing the same, and anti-allergic agent
TW505634B (en) * 1998-01-19 2002-10-11 Dainippon Ink & Amp Chemicals Quinolinone glucoside, the process for preparing thereof and antiallergic
CA2349663C (en) * 1999-09-10 2006-10-31 Dainippon Ink And Chemicals, Inc. Quinolinone derivative formulation and its production method
US6706733B2 (en) 2001-05-08 2004-03-16 Dainippon Ink And Chemicals, Inc. Quinolinone derivative formulation and its production method
KR100908418B1 (ko) 2001-06-20 2009-07-21 액티버스 파마 컴퍼니 리미티드 퀴놀리논 유도체 의약 조성물 및 그의 제조 방법
JP4662727B2 (ja) * 2003-07-30 2011-03-30 マリポーサ・ヘルス・リミテッド 慢性閉塞性肺疾患治療剤
US8980914B2 (en) 2003-07-30 2015-03-17 Mariposa Health Limited Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same
JP2017523213A (ja) * 2014-08-06 2017-08-17 ノバルティス アーゲー 抗菌薬としてのキノロン誘導体
JPWO2018199224A1 (ja) * 2017-04-27 2020-03-12 テイカ製薬株式会社 抗アレルギー剤

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190659A (en) * 1973-08-27 1980-02-26 Sandoz, Inc. Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters
US4192876A (en) * 1975-07-23 1980-03-11 Sandoz, Inc. 4-Hydroxy-3-nitro-quinoline-2(1H)-ones
US4127574A (en) 1976-03-01 1978-11-28 Sandoz, Inc. 4-Hydroxy-3-sulfonyl-quinolin-2(1H)-ones
US4124587A (en) 1976-03-01 1978-11-07 Sandoz, Inc. 4-Hydroxy-3-sulfinyl-quinolin-2(1H)-ones
JPS58225065A (ja) * 1982-06-21 1983-12-27 Nippon Shinyaku Co Ltd ２−キノロン誘導体
DE69113115T2 (de) 1990-05-31 1996-06-13 Merck Sharp & Dohme Dioxo-tetrahydrochinolinderivate.
US5190956A (en) * 1990-09-07 1993-03-02 Schering Corporation Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections
US5179107A (en) 1990-09-07 1993-01-12 Schering Corporation Antiviral quinolinone compounds
AU8448491A (en) 1990-09-07 1992-03-30 Schering Corporation Antiviral compounds and antihypertensive compounds
DE69128481T2 (de) 1990-09-07 1998-04-09 Schering Corp Antivirale und antihypertensive verbindungen
GB9022785D0 (en) 1990-10-19 1990-12-05 Merck Sharp & Dohme Therapeutic agents
US5457099A (en) * 1992-07-02 1995-10-10 Sawai Pharmaceutical Co., Ltd. Carbostyril derivatives and antiallergic agent
EP0685466A1 (de) 1994-06-02 1995-12-06 Ciba-Geigy Ag 3-Heteroaliphatyl- und 3-Hetero-(aryl)aliphatyl-2(1H)-chinolonderivate
US5597922A (en) 1994-07-29 1997-01-28 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Glycine receptor antagonist pharmacophore

Also Published As

Publication number Publication date
TW445258B (en) 2001-07-11
EP0785190A2 (en) 1997-07-23
CA2195031C (en) 2001-06-12
JPH09255659A (ja) 1997-09-30
AU685034B2 (en) 1998-01-08
ATE195517T1 (de) 2000-09-15
US5942521A (en) 1999-08-24
KR100210879B1 (ko) 1999-07-15
CN1275564A (zh) 2000-12-06
US6114352A (en) 2000-09-05
EP0785190B1 (en) 2000-08-16
CN1163268A (zh) 1997-10-29
EP0785190A3 (enExample) 1997-08-27
CA2195031A1 (en) 1997-07-18
JP2943725B2 (ja) 1999-08-30
CN1095834C (zh) 2002-12-11
AU1018497A (en) 1997-07-24
DE69702775D1 (de) 2000-09-21
KR970059167A (ko) 1997-08-12
CN1158265C (zh) 2004-07-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ACTIVUS PHARMA CO.,LTD., YOTSUKAIDO, CHIBA, JP

8327 Change in the person/name/address of the patent owner

Owner name: MARIPOSA HEALTH LTD., BILGOLA PLATEAU, NEW SOU, AU