DE69623595T2 - Verfahren zur behandlung hyperproliferativer epithel-läsionen durch topische verabreichung von hydroxylierten aromatischen protein-crosslinking verbindungen - Google Patents
Verfahren zur behandlung hyperproliferativer epithel-läsionen durch topische verabreichung von hydroxylierten aromatischen protein-crosslinking verbindungenInfo
- Publication number
- DE69623595T2 DE69623595T2 DE69623595T DE69623595T DE69623595T2 DE 69623595 T2 DE69623595 T2 DE 69623595T2 DE 69623595 T DE69623595 T DE 69623595T DE 69623595 T DE69623595 T DE 69623595T DE 69623595 T2 DE69623595 T2 DE 69623595T2
- Authority
- DE
- Germany
- Prior art keywords
- topical administration
- hyperproliferative epithelial
- treating hyperproliferative
- crosslinking compounds
- epithelial lesions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/389,845 US5610185A (en) | 1995-02-17 | 1995-02-17 | Method for the treatment of hyperproliferative epithelial skin diseases by topical application of hydroxylated aromatic protein cross-linking compounds |
PCT/US1996/002301 WO1996025159A1 (en) | 1995-02-17 | 1996-02-14 | A method for the treatment of hyperproliferative epithelial skin diseases by topical application of hydroxylated aromatic protein cross-linking compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69623595D1 DE69623595D1 (de) | 2002-10-17 |
DE69623595T2 true DE69623595T2 (de) | 2003-05-22 |
Family
ID=23539975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69623595T Expired - Lifetime DE69623595T2 (de) | 1995-02-17 | 1996-02-14 | Verfahren zur behandlung hyperproliferativer epithel-läsionen durch topische verabreichung von hydroxylierten aromatischen protein-crosslinking verbindungen |
Country Status (11)
Country | Link |
---|---|
US (1) | US5610185A (de) |
EP (1) | EP0809493B1 (de) |
JP (1) | JPH11503111A (de) |
AT (1) | ATE223715T1 (de) |
AU (1) | AU698414B2 (de) |
CA (1) | CA2212888C (de) |
DE (1) | DE69623595T2 (de) |
DK (1) | DK0809493T3 (de) |
ES (1) | ES2183938T3 (de) |
PT (1) | PT809493E (de) |
WO (1) | WO1996025159A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2321307A1 (en) | 1998-02-27 | 1999-09-02 | Venkatachala L. Narayanan | Disubstituted lavendustin a analogs and pharmaceutical compositions comprising the analogs |
FR2778560B1 (fr) | 1998-05-12 | 2001-06-01 | Oreal | Utilisation de l'acide cinnamique ou d'au moins l'un de ses derives dans une composition destinee a favoriser la desquamation de la peau, et composition le comprenant |
GB2370989A (en) * | 2001-01-16 | 2002-07-17 | Btg Int Ltd | Piperine analogues for the treatment of skin conditions |
PT1511710E (pt) * | 2002-05-31 | 2014-02-26 | Proteotech Inc | Compostos, composições e métodos para o tratamento de doenças da amiloide e sinucleínopatias tais como doença de alzheimer, diabetes do tipo 2, e doença de parkinson |
US7368593B1 (en) | 2003-08-18 | 2008-05-06 | Organics L.L.C. | Method of selective esterification |
US20080125485A1 (en) | 2004-02-17 | 2008-05-29 | Action Medicines | Use of 2,5-Dihydroxybenzene Derivatives for Treating Actinic Keratosis |
ES2238924B1 (es) | 2004-02-17 | 2006-12-01 | Investread Europa, S.L. | Uso del acido 2,5-dihidroxibencenosulfonico, en la fabricacion de medicamentos de aplicacion en el tratamiento de enfermedades angiodependientes. |
US20070149618A1 (en) | 2004-02-17 | 2007-06-28 | Action Medicines, S.L. | Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis |
WO2005092322A1 (ja) * | 2004-03-29 | 2005-10-06 | Japan Health Sciences Foundation | Rar活性化を起こす天然化合物 |
US7351739B2 (en) * | 2004-04-30 | 2008-04-01 | Wellgen, Inc. | Bioactive compounds and methods of uses thereof |
FR2892923B1 (fr) * | 2005-11-08 | 2009-01-16 | Engelhard Lyon Sa | Utilisatiion des derives de l'acide para-coumarique ou para- hydroxycinnamique dans des compositions cosmetiques ou dermatologiques. |
US8541467B2 (en) | 2006-08-16 | 2013-09-24 | Action Medicines, S.L. | Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of hematological dyscrasias and cancer of an organ |
US20080114075A1 (en) | 2006-08-16 | 2008-05-15 | Action Medicines | Use of 2,5-Dihydroxybenzene Derivatives for Treating Dermatitis |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2492815A1 (fr) * | 1980-10-23 | 1982-04-30 | Sori Soc Rech Ind | Nouveau derive d'acide cinnamoyl-cinnamique, son procede de preparation et son application en therapeutique |
US4925877A (en) * | 1986-02-25 | 1990-05-15 | Zaidanhojin Biseibutsu Kagaku Kenkyukai | Physiologically active erbstatin analogue compounds and compositions |
FR2601670B1 (fr) * | 1986-07-17 | 1988-10-07 | Cird | Nouveaux derives bicycliques aromatiques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique |
JPH03109323A (ja) * | 1989-09-22 | 1991-05-09 | Microbial Chem Res Found | 抗ガン剤 |
US5360815A (en) * | 1993-06-23 | 1994-11-01 | Merck Frosst Canada, Inc. | Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis |
JPH0761919A (ja) * | 1993-08-26 | 1995-03-07 | Kao Corp | 美白剤 |
-
1995
- 1995-02-17 US US08/389,845 patent/US5610185A/en not_active Expired - Lifetime
-
1996
- 1996-02-14 JP JP8525201A patent/JPH11503111A/ja not_active Ceased
- 1996-02-14 AU AU49286/96A patent/AU698414B2/en not_active Ceased
- 1996-02-14 CA CA002212888A patent/CA2212888C/en not_active Expired - Lifetime
- 1996-02-14 PT PT96905555T patent/PT809493E/pt unknown
- 1996-02-14 AT AT96905555T patent/ATE223715T1/de not_active IP Right Cessation
- 1996-02-14 DE DE69623595T patent/DE69623595T2/de not_active Expired - Lifetime
- 1996-02-14 WO PCT/US1996/002301 patent/WO1996025159A1/en active IP Right Grant
- 1996-02-14 ES ES96905555T patent/ES2183938T3/es not_active Expired - Lifetime
- 1996-02-14 EP EP96905555A patent/EP0809493B1/de not_active Expired - Lifetime
- 1996-02-14 DK DK96905555T patent/DK0809493T3/da active
Also Published As
Publication number | Publication date |
---|---|
CA2212888A1 (en) | 1996-08-22 |
EP0809493B1 (de) | 2002-09-11 |
EP0809493A1 (de) | 1997-12-03 |
ES2183938T3 (es) | 2003-04-01 |
DE69623595D1 (de) | 2002-10-17 |
PT809493E (pt) | 2003-01-31 |
AU698414B2 (en) | 1998-10-29 |
CA2212888C (en) | 2006-10-17 |
DK0809493T3 (da) | 2002-12-23 |
JPH11503111A (ja) | 1999-03-23 |
ATE223715T1 (de) | 2002-09-15 |
US5610185A (en) | 1997-03-11 |
WO1996025159A1 (en) | 1996-08-22 |
AU4928696A (en) | 1996-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |