DE69623303T2 - Pufferzusammensetzung fur immunologische reagenzien - Google Patents
Pufferzusammensetzung fur immunologische reagenzienInfo
- Publication number
- DE69623303T2 DE69623303T2 DE69623303T DE69623303T DE69623303T2 DE 69623303 T2 DE69623303 T2 DE 69623303T2 DE 69623303 T DE69623303 T DE 69623303T DE 69623303 T DE69623303 T DE 69623303T DE 69623303 T2 DE69623303 T2 DE 69623303T2
- Authority
- DE
- Germany
- Prior art keywords
- composition
- acid
- range
- concentration
- biological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 229960000554 metrizamide Drugs 0.000 description 1
- 229960004712 metrizoic acid Drugs 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 229940083575 sodium dodecyl sulfate Drugs 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000004960 subcellular localization Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940108519 trasylol Drugs 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Detergent Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/482,710 US5616460A (en) | 1995-06-07 | 1995-06-07 | Buffer composition for reagents for immunoassay |
| PCT/US1996/007745 WO1996041164A1 (en) | 1995-06-07 | 1996-05-24 | Buffer composition for reagents for immunoassay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69623303D1 DE69623303D1 (de) | 2002-10-02 |
| DE69623303T2 true DE69623303T2 (de) | 2003-04-17 |
Family
ID=23917128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69623303T Expired - Fee Related DE69623303T2 (de) | 1995-06-07 | 1996-05-24 | Pufferzusammensetzung fur immunologische reagenzien |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5616460A (enExample) |
| EP (1) | EP0852009B1 (enExample) |
| JP (2) | JP4101874B2 (enExample) |
| AT (1) | ATE223046T1 (enExample) |
| DE (1) | DE69623303T2 (enExample) |
| ES (1) | ES2184866T3 (enExample) |
| WO (1) | WO1996041164A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| ES2190087T3 (es) * | 1997-06-13 | 2003-07-16 | Genentech Inc | Formulacion estabilizada de un anticuerpo. |
| US6991790B1 (en) | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
| EP1021723B1 (en) * | 1997-09-22 | 2008-12-10 | Novartis Vaccines and Diagnostics, Inc. | Buffers for stabilizing hcv antigens |
| JP4124961B2 (ja) | 1997-09-22 | 2008-07-23 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | サンプル中の抗体を検出する方法 |
| TR200003024T2 (tr) * | 1998-04-17 | 2000-12-21 | Innogenetics N.V. | İndirgeme ajanlarını kullanarak geliştirilen immünodiagnostik tahliller. |
| BR9906660A (pt) | 1998-07-30 | 2000-08-29 | Advanced Life Science Inst Inc | Processo para medir vìrus da hepatite c |
| US6623921B2 (en) | 1998-07-30 | 2003-09-23 | Advanced Life Science Institute, Inc. | Method for measurement of hepatitis C virus |
| DE10013794A1 (de) * | 2000-03-15 | 2001-10-11 | Gluesenkamp Karl Heinz | Herstellung, Stabilisierung und Anwendung einer neuen Art von chemisch aktivierten Oberflächen |
| AU2001273264A1 (en) * | 2000-07-21 | 2002-02-05 | Cuno, Incorporated | Improved blocking chemistries for nylon membrane |
| WO2002016947A2 (en) * | 2000-08-21 | 2002-02-28 | Queen's University At Kingston | Methods and kits for separation and detection of proteins in biological samples |
| US20030170618A1 (en) * | 2001-02-02 | 2003-09-11 | Chien David Y. | Buffers for stabilizing antigens |
| SG118120A1 (en) * | 2001-03-28 | 2006-01-27 | Ortho Clinical Diagnostics Inc | A hepatitis C antigen - antibody combination assayfor the early detection of HCV infection |
| JP2003066047A (ja) * | 2001-06-14 | 2003-03-05 | Matsushita Electric Ind Co Ltd | 免疫反応測定方法及びそれに用いる免疫反応測定用試薬 |
| US7101683B2 (en) | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
| CH698246B1 (de) * | 2001-12-20 | 2009-06-30 | Hoffmann La Roche | Test zur Identifizierung von Inhibitoren von Beta-Sekretasen. |
| US20030157556A1 (en) * | 2002-02-13 | 2003-08-21 | Maggiore Jack A. | Biological fluid stabilizing composition and method of use thereof |
| US7083912B2 (en) * | 2002-05-31 | 2006-08-01 | Penn State Research Foundation | MAb-based Dot-ELISA method and assay kit for the detection of viruses |
| US20040152070A1 (en) * | 2003-02-04 | 2004-08-05 | Shah Dinesh O. | Method of detection of HCV antibodies in combination assay or sole antibody assay |
| US20050014136A1 (en) * | 2003-05-28 | 2005-01-20 | Innogenetics N.V. | Modified HCV NS5 |
| CA2544185C (en) * | 2003-10-28 | 2010-09-28 | Advanced Life Science Institute, Inc. | Method of detecting hepatitis c virus |
| CN104090097B (zh) * | 2004-02-26 | 2017-04-12 | 康多尔生物技术有限公司 | 一种用作结合对的特异性结合反应培养基的水溶液 |
| CN1922487A (zh) | 2004-02-26 | 2007-02-28 | 康多尔生物技术有限公司 | 一种用作结合对的特异性结合反应培养基的水溶液 |
| US7867443B2 (en) * | 2004-07-23 | 2011-01-11 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
| US20080108147A1 (en) * | 2006-11-03 | 2008-05-08 | Tie Wei | Reduction of non-specific binding in immunoassays |
| JP2007084579A (ja) * | 2006-12-28 | 2007-04-05 | Mitsubishi Pharma Corp | ヘパリン溶液入りプレフィルドシリンジ製剤およびその製造方法 |
| US8617820B2 (en) * | 2007-08-28 | 2013-12-31 | Ortho-Clinical Diagnostics, Inc. | Use of glycosaminoglycans to reduce non-specific binding in immunoassays |
| JP5416159B2 (ja) * | 2011-03-31 | 2014-02-12 | 富士フイルム株式会社 | 高感度なイムノクロマトグラフ方法 |
| CN103630690B (zh) * | 2013-12-17 | 2014-08-20 | 朱之炜 | 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法 |
| EP3258270B1 (en) * | 2015-02-10 | 2019-05-29 | Shenzhen New Industries Biomedical Engineering Co. Ltd. | Cardiac troponin i ultra-sensitive detection reagent kit, and ultra-sensitive detection method therefor |
| US12493034B2 (en) * | 2021-01-08 | 2025-12-09 | George Mason University | Reagent buffer |
| CN114200125B (zh) * | 2021-12-06 | 2024-02-13 | 武汉生之源生物科技股份有限公司 | 一种不含蛋白的碱性磷酸酶-抗体偶联物稀释液及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59198999A (ja) * | 1983-04-27 | 1984-11-10 | Denka Seiken Co Ltd | クレアチンキナ−ゼ測定用組成物 |
| JPS6339582A (ja) * | 1986-08-04 | 1988-02-20 | Takara Shuzo Co Ltd | 酵素組成物 |
| US4956274A (en) * | 1987-04-06 | 1990-09-11 | Microgenics Corporation | Reagent stabilization in enzyme-donor and acceptor assay |
| US5075221A (en) * | 1988-10-07 | 1991-12-24 | Eastman Kodak Company | Stabilized extraction composition containing a sulfhydryl-containing reducing agent and its use in chlamydial and gonococcal determinations |
| EP0401379B1 (en) * | 1988-12-06 | 1994-06-15 | Otsuka Pharmaceutical Co., Ltd. | STABILIZED COMPOSITION OF INTERLEUKIN-1$g(b) |
| ATE194844T1 (de) * | 1990-04-06 | 2000-08-15 | Genelabs Tech Inc | Hepatitis c-virus-epitope |
| ATE191792T1 (de) * | 1991-09-16 | 2000-04-15 | Abbott Lab | Verfahren zur detektion von hepatitis c |
| US5376313A (en) * | 1992-03-27 | 1994-12-27 | Abbott Laboratories | Injection molding a plastic assay cuvette having low birefringence |
| GR1001480B (el) * | 1992-12-29 | 1994-02-28 | Eyaggelia Protopapa | Ενζυμικά σκευάσματα περιέχοντα παπαϊνη ή χυμο?ρυψίνη και μέ?οδοι μόνιμης ενζυμικής αποτρίχωσης. |
-
1995
- 1995-06-07 US US08/482,710 patent/US5616460A/en not_active Expired - Lifetime
-
1996
- 1996-05-24 DE DE69623303T patent/DE69623303T2/de not_active Expired - Fee Related
- 1996-05-24 EP EP96916655A patent/EP0852009B1/en not_active Expired - Lifetime
- 1996-05-24 AT AT96916655T patent/ATE223046T1/de not_active IP Right Cessation
- 1996-05-24 ES ES96916655T patent/ES2184866T3/es not_active Expired - Lifetime
- 1996-05-24 JP JP50073897A patent/JP4101874B2/ja not_active Expired - Lifetime
- 1996-05-24 WO PCT/US1996/007745 patent/WO1996041164A1/en not_active Ceased
- 1996-10-16 US US08/734,435 patent/US5773212A/en not_active Expired - Fee Related
-
2005
- 2005-05-12 JP JP2005139663A patent/JP3930519B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5773212A (en) | 1998-06-30 |
| EP0852009B1 (en) | 2002-08-28 |
| EP0852009A1 (en) | 1998-07-08 |
| JP2001516440A (ja) | 2001-09-25 |
| JP2005300552A (ja) | 2005-10-27 |
| JP4101874B2 (ja) | 2008-06-18 |
| WO1996041164A1 (en) | 1996-12-19 |
| DE69623303D1 (de) | 2002-10-02 |
| US5616460A (en) | 1997-04-01 |
| ATE223046T1 (de) | 2002-09-15 |
| JP3930519B2 (ja) | 2007-06-13 |
| ES2184866T3 (es) | 2003-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |