DE69617261T2 - Verfahren zur herstellung von magnesium pyridoxal-5'-phosphorsäureester-glutaminat und dabei hergestellte zwischenprodukte - Google Patents
Verfahren zur herstellung von magnesium pyridoxal-5'-phosphorsäureester-glutaminat und dabei hergestellte zwischenprodukteInfo
- Publication number
- DE69617261T2 DE69617261T2 DE69617261T DE69617261T DE69617261T2 DE 69617261 T2 DE69617261 T2 DE 69617261T2 DE 69617261 T DE69617261 T DE 69617261T DE 69617261 T DE69617261 T DE 69617261T DE 69617261 T2 DE69617261 T2 DE 69617261T2
- Authority
- DE
- Germany
- Prior art keywords
- glutaminate
- acid ester
- phosphoric acid
- products produced
- intermediate products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 title 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-M glutaminate Chemical compound [O-]C(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-M 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 229910052749 magnesium Inorganic materials 0.000 title 1
- 239000011777 magnesium Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE69617261T DE69617261T2 (de) | 1995-09-04 | 1996-08-26 | Verfahren zur herstellung von magnesium pyridoxal-5'-phosphorsäureester-glutaminat und dabei hergestellte zwischenprodukte |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19532625A DE19532625C2 (de) | 1995-09-04 | 1995-09-04 | Verfahren zur Herstellung von Magnesium-pyridoxal-5'-phosphat-glutamat und dabei erhaltene Zwischenprodukte |
| DE69617261T DE69617261T2 (de) | 1995-09-04 | 1996-08-26 | Verfahren zur herstellung von magnesium pyridoxal-5'-phosphorsäureester-glutaminat und dabei hergestellte zwischenprodukte |
| PCT/EP1996/003749 WO1997009334A1 (en) | 1995-09-04 | 1996-08-26 | Method for the production of magnesium pyridoxal-5'-phosphate glutamate and intermediate products obtained thereby |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69617261D1 DE69617261D1 (de) | 2002-01-03 |
| DE69617261T2 true DE69617261T2 (de) | 2002-05-08 |
Family
ID=7771233
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19532625A Expired - Fee Related DE19532625C2 (de) | 1995-09-04 | 1995-09-04 | Verfahren zur Herstellung von Magnesium-pyridoxal-5'-phosphat-glutamat und dabei erhaltene Zwischenprodukte |
| DE69617261T Expired - Fee Related DE69617261T2 (de) | 1995-09-04 | 1996-08-26 | Verfahren zur herstellung von magnesium pyridoxal-5'-phosphorsäureester-glutaminat und dabei hergestellte zwischenprodukte |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19532625A Expired - Fee Related DE19532625C2 (de) | 1995-09-04 | 1995-09-04 | Verfahren zur Herstellung von Magnesium-pyridoxal-5'-phosphat-glutamat und dabei erhaltene Zwischenprodukte |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5962687A (de) |
| EP (1) | EP0861258B1 (de) |
| JP (1) | JPH11512103A (de) |
| KR (1) | KR19990044359A (de) |
| CN (1) | CN1199402A (de) |
| AR (1) | AR003488A1 (de) |
| AT (1) | ATE209210T1 (de) |
| AU (1) | AU706162B2 (de) |
| BA (1) | BA96127A (de) |
| CA (1) | CA2230555A1 (de) |
| CO (1) | CO4750659A1 (de) |
| CZ (1) | CZ292662B6 (de) |
| DE (2) | DE19532625C2 (de) |
| DK (1) | DK0861258T3 (de) |
| EG (1) | EG20974A (de) |
| ES (1) | ES2165521T3 (de) |
| HK (1) | HK1014958A1 (de) |
| HR (1) | HRP960401B1 (de) |
| HU (1) | HUP9802778A3 (de) |
| JO (1) | JO1921B1 (de) |
| NZ (1) | NZ318374A (de) |
| PL (1) | PL325333A1 (de) |
| PT (1) | PT861258E (de) |
| TW (1) | TW442472B (de) |
| WO (1) | WO1997009334A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003237088A1 (en) * | 2002-04-23 | 2003-11-10 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing viral infections and associated diseases |
| BRPI0820832A2 (pt) * | 2007-12-14 | 2015-06-16 | Pledpharma Ab | Composto, uso de um composto, método de tratamento de câncer, composição farmacêutica, kit , e, uso de uma composição farmacêutica. |
| CN106946932A (zh) * | 2017-03-21 | 2017-07-14 | 上海津力生物科技股份有限公司 | 一种吡哆醛‑5‑磷酸酯的制备方法 |
| CN108976259A (zh) * | 2017-06-01 | 2018-12-11 | 上海凯赛生物技术研发中心有限公司 | 一种磷酸吡哆醛的合成方法 |
| CN107652323A (zh) * | 2017-09-20 | 2018-02-02 | 精晶药业股份有限公司 | 一种磷酸吡哆醛的合成方法 |
| CN108754160B (zh) * | 2018-07-26 | 2020-05-08 | 江苏理工学院 | 一种吡哆醛含锰废水的回收利用方法 |
| CN110016049A (zh) * | 2019-03-18 | 2019-07-16 | 武汉工程大学 | 一种磷酸吡哆醛的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3663557A (en) * | 1966-06-08 | 1972-05-16 | Kogerim Ets | Biologically active forms of pyridoxine coenzymes |
| US3854559A (en) * | 1973-10-01 | 1974-12-17 | Deere & Co | Control system for a hydraulically-operable brake and transmission |
| ES421396A3 (es) * | 1973-12-12 | 1976-04-16 | Vila Busquets | Procedimiento para la fabricacion del fosfato de piridoxal. |
| DE2461742C2 (de) * | 1974-12-28 | 1983-01-27 | Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt | Pyridoxin-5'-phosphorsäureester-Derivate sowie deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE4016963A1 (de) * | 1990-05-25 | 1991-11-28 | Steigerwald Arzneimittelwerk | Verwendung von magnesium-pyridoxal-5'-phosphat-glutaminat zur verhinderung von erkrankungen, die sich infolge von gefaessschaeden ergeben |
-
1995
- 1995-09-04 DE DE19532625A patent/DE19532625C2/de not_active Expired - Fee Related
-
1996
- 1996-08-26 EP EP96930965A patent/EP0861258B1/de not_active Expired - Lifetime
- 1996-08-26 HU HU9802778A patent/HUP9802778A3/hu unknown
- 1996-08-26 ES ES96930965T patent/ES2165521T3/es not_active Expired - Lifetime
- 1996-08-26 KR KR1019980701601A patent/KR19990044359A/ko not_active Application Discontinuation
- 1996-08-26 NZ NZ318374A patent/NZ318374A/xx unknown
- 1996-08-26 CN CN96197528A patent/CN1199402A/zh active Pending
- 1996-08-26 AU AU69845/96A patent/AU706162B2/en not_active Ceased
- 1996-08-26 US US09/029,426 patent/US5962687A/en not_active Expired - Fee Related
- 1996-08-26 CA CA002230555A patent/CA2230555A1/en not_active Abandoned
- 1996-08-26 AT AT96930965T patent/ATE209210T1/de not_active IP Right Cessation
- 1996-08-26 JP JP9510820A patent/JPH11512103A/ja active Pending
- 1996-08-26 WO PCT/EP1996/003749 patent/WO1997009334A1/en active IP Right Grant
- 1996-08-26 DK DK96930965T patent/DK0861258T3/da active
- 1996-08-26 DE DE69617261T patent/DE69617261T2/de not_active Expired - Fee Related
- 1996-08-26 CZ CZ1998591A patent/CZ292662B6/cs not_active IP Right Cessation
- 1996-08-26 PL PL96325333A patent/PL325333A1/xx unknown
- 1996-08-26 PT PT96930965T patent/PT861258E/pt unknown
- 1996-08-30 BA BA960127A patent/BA96127A/bs unknown
- 1996-08-31 EG EG79496A patent/EG20974A/xx active
- 1996-09-02 JO JO19961921A patent/JO1921B1/en active
- 1996-09-03 HR HR960401A patent/HRP960401B1/xx not_active IP Right Cessation
- 1996-09-03 TW TW085110753A patent/TW442472B/zh not_active IP Right Cessation
- 1996-09-03 AR ARP960104206A patent/AR003488A1/es active IP Right Grant
- 1996-09-04 CO CO96047151A patent/CO4750659A1/es unknown
-
1999
- 1999-01-04 HK HK99100006A patent/HK1014958A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JO1921B1 (en) | 1997-01-15 |
| AU706162B2 (en) | 1999-06-10 |
| DE19532625A1 (de) | 1997-03-06 |
| CZ59198A3 (cs) | 1998-07-15 |
| TW442472B (en) | 2001-06-23 |
| EP0861258B1 (de) | 2001-11-21 |
| DE19532625C2 (de) | 2000-04-20 |
| CZ292662B6 (cs) | 2003-11-12 |
| HRP960401A2 (en) | 1998-02-28 |
| AU6984596A (en) | 1997-03-27 |
| EG20974A (en) | 2000-08-30 |
| HUP9802778A2 (hu) | 1999-09-28 |
| CN1199402A (zh) | 1998-11-18 |
| EP0861258A1 (de) | 1998-09-02 |
| JPH11512103A (ja) | 1999-10-19 |
| HRP960401B1 (en) | 2001-10-31 |
| WO1997009334A1 (en) | 1997-03-13 |
| KR19990044359A (ko) | 1999-06-25 |
| DK0861258T3 (da) | 2002-05-21 |
| US5962687A (en) | 1999-10-05 |
| HUP9802778A3 (en) | 2001-02-28 |
| DE69617261D1 (de) | 2002-01-03 |
| CA2230555A1 (en) | 1997-03-13 |
| CO4750659A1 (es) | 1999-03-31 |
| PT861258E (pt) | 2002-05-31 |
| AR003488A1 (es) | 1998-08-05 |
| HK1014958A1 (en) | 1999-10-08 |
| BA96127A (bs) | 1998-12-28 |
| NZ318374A (en) | 1999-06-29 |
| ES2165521T3 (es) | 2002-03-16 |
| PL325333A1 (en) | 1998-07-20 |
| ATE209210T1 (de) | 2001-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |