DE69617027D1 - Polymorphs von prodrug 6-n(l-ala-l-ala)-trovafloxacin - Google Patents

Polymorphs von prodrug 6-n(l-ala-l-ala)-trovafloxacin

Info

Publication number
DE69617027D1
DE69617027D1 DE69617027T DE69617027T DE69617027D1 DE 69617027 D1 DE69617027 D1 DE 69617027D1 DE 69617027 T DE69617027 T DE 69617027T DE 69617027 T DE69617027 T DE 69617027T DE 69617027 D1 DE69617027 D1 DE 69617027D1
Authority
DE
Germany
Prior art keywords
ala
trovafloxacin
polymorphs
prodrug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69617027T
Other languages
English (en)
Other versions
DE69617027T2 (de
Inventor
Timothy Norris
J Mcgarry
J Allen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69617027D1 publication Critical patent/DE69617027D1/de
Publication of DE69617027T2 publication Critical patent/DE69617027T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DE69617027T 1995-08-29 1996-07-05 Polymorphs von prodrug 6-n(l-ala-l-ala)-trovafloxacin Expired - Fee Related DE69617027T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US510995P 1995-08-29 1995-08-29
PCT/IB1996/000653 WO1997008191A1 (en) 1995-08-29 1996-07-05 Polymorphs of the prodrug 6-n-(l-ala-l-ala)-trovafloxacin

Publications (2)

Publication Number Publication Date
DE69617027D1 true DE69617027D1 (de) 2001-12-20
DE69617027T2 DE69617027T2 (de) 2002-03-21

Family

ID=21714229

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69617027T Expired - Fee Related DE69617027T2 (de) 1995-08-29 1996-07-05 Polymorphs von prodrug 6-n(l-ala-l-ala)-trovafloxacin

Country Status (35)

Country Link
US (1) US6080756A (de)
EP (1) EP0847400B1 (de)
JP (1) JPH11509188A (de)
KR (1) KR100274736B1 (de)
CN (1) CN1193977A (de)
AP (1) AP639A (de)
AR (1) AR004507A1 (de)
AT (1) ATE208790T1 (de)
AU (1) AU696414B2 (de)
BR (1) BR9610283A (de)
CA (1) CA2230303C (de)
CO (1) CO4480740A1 (de)
CZ (1) CZ291524B6 (de)
DE (1) DE69617027T2 (de)
DK (1) DK0847400T3 (de)
DZ (1) DZ2088A1 (de)
ES (1) ES2164892T3 (de)
GT (1) GT199600061A (de)
HR (1) HRP960396A2 (de)
HU (1) HUP9900226A3 (de)
IL (1) IL122652A (de)
MA (1) MA23965A1 (de)
NO (1) NO309039B1 (de)
NZ (1) NZ310542A (de)
OA (1) OA10670A (de)
PL (1) PL185709B1 (de)
PT (1) PT847400E (de)
RU (1) RU2151152C1 (de)
SK (1) SK283354B6 (de)
TN (1) TNSN96110A1 (de)
TR (1) TR199800340T1 (de)
UA (1) UA48982C2 (de)
WO (1) WO1997008191A1 (de)
YU (1) YU48296A (de)
ZA (1) ZA967281B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000106A (es) * 1997-08-01 1999-01-08 Pfizer Prod Inc Composiciones parenterales de alatroflaxacino
US6239141B1 (en) * 1999-06-04 2001-05-29 Pfizer Inc. Trovafloxacin oral suspensions
CN105510497A (zh) * 2015-11-30 2016-04-20 精晶药业股份有限公司 L-丙氨酰-l-丙氨酸的定量检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids

Also Published As

Publication number Publication date
RU2151152C1 (ru) 2000-06-20
CZ55298A3 (cs) 1999-02-17
PL325203A1 (en) 1998-07-06
US6080756A (en) 2000-06-27
SK283354B6 (sk) 2003-06-03
CO4480740A1 (es) 1997-07-09
PL185709B1 (pl) 2003-07-31
SK23798A3 (en) 1999-05-07
NO309039B1 (no) 2000-12-04
CZ291524B6 (cs) 2003-03-12
KR100274736B1 (ko) 2000-12-15
ATE208790T1 (de) 2001-11-15
UA48982C2 (uk) 2002-09-16
HRP960396A2 (en) 1998-04-30
BR9610283A (pt) 1999-03-16
ES2164892T3 (es) 2002-03-01
MA23965A1 (fr) 1997-04-01
TR199800340T1 (xx) 1998-06-22
CA2230303C (en) 2001-07-24
HUP9900226A2 (hu) 1999-05-28
AR004507A1 (es) 1998-12-16
NO980863L (no) 1998-02-27
AP639A (en) 1998-04-14
KR19990044231A (ko) 1999-06-25
NO980863D0 (no) 1998-02-27
WO1997008191A1 (en) 1997-03-06
AU6135196A (en) 1997-03-19
MX9801665A (es) 1998-08-30
NZ310542A (en) 1999-09-29
OA10670A (en) 2000-11-06
TNSN96110A1 (fr) 2005-03-15
DK0847400T3 (da) 2002-03-25
CA2230303A1 (en) 1997-03-06
YU48296A (sh) 1998-12-23
EP0847400B1 (de) 2001-11-14
ZA967281B (en) 1998-03-02
DE69617027T2 (de) 2002-03-21
HUP9900226A3 (en) 1999-11-29
AU696414B2 (en) 1998-09-10
IL122652A (en) 2000-01-31
JPH11509188A (ja) 1999-08-17
IL122652A0 (en) 1996-08-16
PT847400E (pt) 2002-03-28
DZ2088A1 (fr) 2002-07-22
GT199600061A (es) 1998-01-31
CN1193977A (zh) 1998-09-23
EP0847400A1 (de) 1998-06-17
AP9600854A0 (en) 1996-10-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee