EE200000365A - Bispidiini uued arütmiavastased ühendid - Google Patents

Bispidiini uued arütmiavastased ühendid

Info

Publication number
EE200000365A
EE200000365A EEP200000365A EEP200000365A EE200000365A EE 200000365 A EE200000365 A EE 200000365A EE P200000365 A EEP200000365 A EE P200000365A EE P200000365 A EEP200000365 A EE P200000365A EE 200000365 A EE200000365 A EE 200000365A
Authority
EE
Estonia
Prior art keywords
bispidine
novel anti
arrhythmic compounds
arrhythmic
compounds
Prior art date
Application number
EEP200000365A
Other languages
English (en)
Inventor
Strandlund Gert
Alstermark Christer
Bj�re Annika
Bj�rsne Magnus
Frantsi Marianne
Halvarsson Torbj�rn
Hoffmann Kurt-J�rgen
Lindstedt Eva-Lotte
Polla Magnus
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000365A publication Critical patent/EE200000365A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
EEP200000365A 1997-12-17 1998-12-10 Bispidiini uued arütmiavastased ühendid EE200000365A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704709A SE9704709D0 (sv) 1997-12-17 1997-12-17 Pharmaceutically active compounds
PCT/SE1998/002276 WO1999031100A1 (en) 1997-12-17 1998-12-10 Novel bispidine antiarrhythmic compounds

Publications (1)

Publication Number Publication Date
EE200000365A true EE200000365A (et) 2001-10-15

Family

ID=20409426

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000365A EE200000365A (et) 1997-12-17 1998-12-10 Bispidiini uued arütmiavastased ühendid

Country Status (28)

Country Link
US (1) US6291475B1 (et)
EP (1) EP1047695B1 (et)
JP (1) JP2002508375A (et)
KR (1) KR20010024723A (et)
CN (1) CN1284956A (et)
AR (1) AR017217A1 (et)
AT (1) ATE261964T1 (et)
AU (1) AU1795399A (et)
BR (1) BR9813668A (et)
CA (1) CA2314490A1 (et)
DE (1) DE69822513T2 (et)
DK (1) DK1047695T3 (et)
EE (1) EE200000365A (et)
ES (1) ES2216337T3 (et)
HU (1) HUP0102307A3 (et)
ID (1) ID24638A (et)
IL (1) IL136374A0 (et)
IS (1) IS5522A (et)
NO (1) NO20003137L (et)
NZ (1) NZ504909A (et)
PL (1) PL341388A1 (et)
PT (1) PT1047695E (et)
SE (1) SE9704709D0 (et)
SI (1) SI1047695T1 (et)
SK (1) SK7812000A3 (et)
TR (1) TR200001757T2 (et)
WO (1) WO1999031100A1 (et)
ZA (1) ZA9811130B (et)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9803517D0 (sv) * 1998-10-15 1998-10-15 Astra Ab Pharmaceutical preparation
TWI229674B (en) 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
SE9902269D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902270D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902268D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902271D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
US20050004113A1 (en) * 1999-06-16 2005-01-06 Astrazeneca Ab New bispidine compounds useful in the treatment of cardiac arrhythmias
US7038054B1 (en) * 1999-09-03 2006-05-02 Pharmacopeia Drug Discovery, Inc. Diazabicyclononane scaffold for combinatorial synthesis
SE9903759D0 (sv) 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
JP2003516988A (ja) * 1999-12-14 2003-05-20 ニューロサーチ、アクティーゼルスカブ 新規ヘテロアリール−ジアザビシクロアルカン類
SE9904765D0 (sv) 1999-12-23 1999-12-23 Astra Ab Pharmaceutically-useful compounds
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios
SE0002603D0 (sv) * 2000-07-07 2000-07-07 Astrazeneca Ab New compounds
US6808924B1 (en) 2000-07-11 2004-10-26 Claudia Lanari Mouse mammary tumor lines expressing estrogen and progesterone receptors
AR030756A1 (es) 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
SE0003795D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
SE0100326D0 (sv) 2001-02-02 2001-02-02 Astrazeneca Ab New compounds
SE0101327D0 (sv) * 2001-04-12 2001-04-12 Astrazeneca Ab New crystalline forms
SE0101329D0 (sv) * 2001-04-12 2001-04-12 Astrazeneca Ab Pharmaceutical formulation
TWI259836B (en) * 2001-04-12 2006-08-11 Astrazeneca Ab Modified release formulation suitable for antiarrhythmic compounds
SE0101324D0 (sv) * 2001-04-12 2001-04-12 Astrazeneca Ab New process
WO2002096911A1 (en) * 2001-06-01 2002-12-05 Neurosearch A/S Novel heteroaryl-diazabicyclo-alkanes as cns-modulators
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
EP1730145A1 (en) * 2004-03-22 2006-12-13 Boehringer Ingelheim Pharmaceuticals Inc. Alpha-trifluoromethyl alcohols or amines as glucocorticoid mimetics
SE0401540D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
MX2007015800A (es) 2005-06-13 2008-03-04 Astrazeneca Ab Compuestos de oxabispidina novedosos para el tratamiento de arritmias cardiacas.
CN102485725B (zh) * 2010-12-02 2015-07-22 武汉药明康德新药开发有限公司 一种双氮杂环桥环类药物模板及其制备方法和应用
WO2012172043A1 (en) 2011-06-15 2012-12-20 Laboratoire Biodim Purine derivatives and their use as pharmaceuticals for prevention or treatment of bacterial infections
CN102875550B (zh) * 2011-07-12 2016-01-06 常州合全药业有限公司 1,3,7-三取代-3,7-二氮杂双环[3,3,1]壬烷衍生物及制备方法
CN104151277A (zh) * 2014-06-30 2014-11-19 北京万全德众医药生物技术有限公司 盐酸决奈达隆一种氧化杂质的制备方法
CN113683585B (zh) * 2021-09-26 2023-07-11 齐鲁工业大学 一种含环氧基邻苯二甲腈单体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
FR2713081B1 (fr) 1993-11-29 1996-01-12 Celsa Lg Filtre sanguin perfectionné à deux séries de pattes en pétales.

Also Published As

Publication number Publication date
KR20010024723A (ko) 2001-03-26
DE69822513D1 (de) 2004-04-22
US6291475B1 (en) 2001-09-18
ATE261964T1 (de) 2004-04-15
SI1047695T1 (en) 2004-08-31
TR200001757T2 (tr) 2000-09-21
IS5522A (is) 2000-06-02
NO20003137D0 (no) 2000-06-16
ID24638A (id) 2000-07-27
HUP0102307A2 (hu) 2001-12-28
JP2002508375A (ja) 2002-03-19
AR017217A1 (es) 2001-08-22
EP1047695B1 (en) 2004-03-17
AU1795399A (en) 1999-07-05
NO20003137L (no) 2000-08-17
PT1047695E (pt) 2004-07-30
ZA9811130B (en) 1999-06-17
SE9704709D0 (sv) 1997-12-17
WO1999031100A1 (en) 1999-06-24
ES2216337T3 (es) 2004-10-16
DK1047695T3 (da) 2004-06-28
IL136374A0 (en) 2001-06-14
SK7812000A3 (en) 2001-05-10
EP1047695A1 (en) 2000-11-02
NZ504909A (en) 2001-11-30
DE69822513T2 (de) 2005-03-10
HUP0102307A3 (en) 2002-02-28
PL341388A1 (en) 2001-04-09
BR9813668A (pt) 2000-10-17
CN1284956A (zh) 2001-02-21
CA2314490A1 (en) 1999-06-24

Similar Documents

Publication Publication Date Title
EE200000365A (et) Bispidiini uued arütmiavastased ühendid
CY2012029I2 (el) Nεα μορφη της 5-ομεπραζολης
EE200000321A (et) Uudsed ühendid
EE200000044A (et) Uued ühendid
ID22850A (id) Senyawa-senyawa pirazina
ID24458A (id) Modifikasi rheologi in-sito poliolefin
ID20323A (id) Senyawa-senyawa triazinilaminostilbena
IS5208A (is) Efnasambönd
ID24327A (id) Produksi senyawa-senyawa avermektin
EE9900475A (et) Ühendid
ID22983A (id) Senyawa-senyawa fluorometoksimino
EE9900602A (et) Ühendid
DE69811256T2 (de) Polymorphe modifikationen von dofetilid
EE9900466A (et) Ühendid
DE69737634D1 (de) Insektizide oxadiazinverbindungen
SE9702775D0 (sv) Novel compounds
SE9704403D0 (sv) Novel compounds
SE9701099D0 (sv) Novel compounds
SE9701194D0 (sv) Novel compounds
SE9702200D0 (sv) Novel compounds
SE9702652D0 (sv) Novel compounds
SE9701767D0 (sv) Novel compounds
SE9703735D0 (sv) Novel compounds
SE9701098D0 (sv) Novel compounds
SE9701100D0 (sv) Novel compounds