EE200000321A - Uudsed ühendid - Google Patents

Uudsed ühendid

Info

Publication number
EE200000321A
EE200000321A EEP200000321A EEP200000321A EE200000321A EE 200000321 A EE200000321 A EE 200000321A EE P200000321 A EEP200000321 A EE P200000321A EE P200000321 A EEP200000321 A EE P200000321A EE 200000321 A EE200000321 A EE 200000321A
Authority
EE
Estonia
Prior art keywords
novel compounds
novel
compounds
Prior art date
Application number
EEP200000321A
Other languages
English (en)
Inventor
Baxter Andrew
Cheshire David
Mcinally Thomas
Mortimore Michael
Cladingboel David
Original Assignee
Astrazeneca Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Limited filed Critical Astrazeneca Uk Limited
Publication of EE200000321A publication Critical patent/EE200000321A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EEP200000321A 1997-12-05 1998-12-01 Uudsed ühendid EE200000321A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704546A SE9704546D0 (sv) 1997-12-05 1997-12-05 Novel compounds
PCT/SE1998/002190 WO1999029686A1 (en) 1997-12-05 1998-12-01 Novel compounds

Publications (1)

Publication Number Publication Date
EE200000321A true EE200000321A (et) 2001-08-15

Family

ID=20409283

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000321A EE200000321A (et) 1997-12-05 1998-12-01 Uudsed ühendid

Country Status (16)

Country Link
EP (1) EP1037889A1 (et)
JP (1) JP2001525406A (et)
KR (1) KR20010032800A (et)
CN (1) CN1284074A (et)
AU (1) AU1791599A (et)
BR (1) BR9813378A (et)
CA (1) CA2312357A1 (et)
EE (1) EE200000321A (et)
HU (1) HUP0100731A3 (et)
IL (1) IL136368A0 (et)
NO (1) NO20002787L (et)
PL (1) PL340837A1 (et)
SE (1) SE9704546D0 (et)
SK (1) SK8442000A3 (et)
TR (1) TR200001544T2 (et)
WO (1) WO1999029686A1 (et)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901875D0 (sv) * 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds
SE9904505D0 (sv) 1999-12-09 1999-12-09 Astra Pharma Prod Novel compounds
SE9904652D0 (sv) * 1999-12-17 1999-12-17 Astra Pharma Prod Novel Compounds
TWI258462B (en) 1999-12-17 2006-07-21 Astrazeneca Ab Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same
JP2002330787A (ja) * 2000-10-21 2002-11-19 Astrazeneca Ab 化学物質
WO2003042190A1 (en) 2001-11-12 2003-05-22 Pfizer Products Inc. N-alkyl-adamantyl derivatives as p2x7-receptor antagonists
PA8557501A1 (es) 2001-11-12 2003-06-30 Pfizer Prod Inc Benzamida, heteroarilamida y amidas inversas
PA8591801A1 (es) 2002-12-31 2004-07-26 Pfizer Prod Inc Inhibidores benzamidicos del receptor p2x7.
US7071223B1 (en) 2002-12-31 2006-07-04 Pfizer, Inc. Benzamide inhibitors of the P2X7 receptor
ES2281801T3 (es) 2003-05-12 2007-10-01 Pfizer Products Inc. Inhibidores benzamida del receptor p2x7.
GB0324498D0 (en) 2003-07-21 2003-11-26 Aventis Pharma Inc Heterocyclic compounds as P2X7 ion channel blockers
BRPI0512781A (pt) 2004-06-29 2008-04-08 Pfizer Prod Inc método para preparação de derivados de 5-{4-(2-hidroxi-propil)-3,5-dioxo-4,5-diidro-3h-[1,2,4]tria zin-2-il}-benzamida através da desproteção dos precursores de protetores de hidroxila
CA2645551C (en) 2006-03-16 2016-06-28 Renovis, Inc. Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
DK2001474T3 (en) 2006-03-16 2016-05-09 Second Genome Inc BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND APPLICATIONS THEREOF
TWI464148B (zh) 2006-03-16 2014-12-11 Evotec Us Inc 作為p2x7調節劑之雙環雜芳基化合物與其用途
TW200813018A (en) 2006-06-09 2008-03-16 Astrazeneca Ab Novel compounds
GB0613473D0 (en) * 2006-07-06 2006-08-16 Glaxo Group Ltd Novel compounds
EA016076B1 (ru) * 2006-07-06 2012-01-30 Глэксо Груп Лимитед Замещенные n-фенилметил-5-оксопролин-2-амиды в качестве антагонистов р2х7-рецептора и способы их применения
CN101686680B (zh) 2007-03-09 2015-12-09 伊沃泰克美国股份有限公司 作为p2x7调节剂的双环杂芳基化合物及其用途
JP2010522711A (ja) * 2007-03-28 2010-07-08 グラクソ グループ リミテッド P2x7調節因子としてのピペリジノンカルボキサミド誘導体
EP2139875A2 (en) * 2007-03-29 2010-01-06 Glaxo Group Limited Oxazolidine and morpholine carboxamide derivatives as p2x7 modulators
MX2009010759A (es) 2007-04-03 2009-10-28 Glaxo Group Ltd Derivados de carboxamida imidazolidina como modulares de p2x7.
US8119661B2 (en) 2007-09-11 2012-02-21 Astrazeneca Ab Piperidine derivatives and their use as muscarinic receptor modulators
GB0803729D0 (en) * 2008-02-29 2008-04-09 Ge Healthcare Ltd Imaging the central nervous system
NZ587799A (en) 2008-03-25 2012-06-29 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
ES2380908T3 (es) 2009-04-14 2012-05-21 Affectis Pharmaceuticals Ag Antagonistas de p2x7r novedosos y su uso
EP2322149A1 (en) 2009-11-03 2011-05-18 Universidad del Pais Vasco Methods and compositions for the treatment of ischemia
JP2013526496A (ja) 2010-05-14 2013-06-24 アフェクティス ファーマシューティカルズ アーゲー P2x7r拮抗剤の新規調製方法
WO2012110190A1 (en) 2011-02-17 2012-08-23 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163456A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
WO2012163792A1 (en) 2011-05-27 2012-12-06 Affectis Pharmaceuticals Ag Novel p2x7r antagonists and their use
AU2018372136B2 (en) 2017-11-21 2022-01-27 Solventum Intellectual Properties Company Oral plant-based-oil-in-water emulsions and methods of use
US11324681B2 (en) 2017-12-20 2022-05-10 3M Innovative Properties Company Oral compositions and methods of use
EP3727336A1 (en) 2017-12-20 2020-10-28 3M Innovative Properties Company Oral compositions and methods of use
WO2020136606A1 (en) 2018-12-29 2020-07-02 3M Innovative Properties Company Oral articles and methods of use
WO2020136620A1 (en) 2018-12-29 2020-07-02 3M Innovative Properties Company Oral articles and methods of use

Also Published As

Publication number Publication date
NO20002787D0 (no) 2000-05-31
SE9704546D0 (sv) 1997-12-05
JP2001525406A (ja) 2001-12-11
SK8442000A3 (en) 2001-01-18
BR9813378A (pt) 2000-10-10
WO1999029686A1 (en) 1999-06-17
KR20010032800A (ko) 2001-04-25
PL340837A1 (en) 2001-02-26
EP1037889A1 (en) 2000-09-27
AU1791599A (en) 1999-06-28
NO20002787L (no) 2000-08-01
CA2312357A1 (en) 1999-06-17
TR200001544T2 (tr) 2000-11-21
IL136368A0 (en) 2001-06-14
CN1284074A (zh) 2001-02-14
HUP0100731A3 (en) 2002-08-28
HUP0100731A2 (hu) 2002-05-29

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