DE69535653D1 - Verfahren zur Herstellung einer D-N-Carbamoyl-alpha-Aminosäure - Google Patents

Verfahren zur Herstellung einer D-N-Carbamoyl-alpha-Aminosäure

Info

Publication number
DE69535653D1
DE69535653D1 DE69535653T DE69535653T DE69535653D1 DE 69535653 D1 DE69535653 D1 DE 69535653D1 DE 69535653 T DE69535653 T DE 69535653T DE 69535653 T DE69535653 T DE 69535653T DE 69535653 D1 DE69535653 D1 DE 69535653D1
Authority
DE
Germany
Prior art keywords
carbamoyl
alpha
preparation
amino acid
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69535653T
Other languages
English (en)
Other versions
DE69535653T2 (de
Inventor
Hirokazu Nanba
Kazuyoshi Yajima
Masayuki Takano
Yukio Yamada
Yasuhiro Ikenaka
Satomi Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Application granted granted Critical
Publication of DE69535653D1 publication Critical patent/DE69535653D1/de
Publication of DE69535653T2 publication Critical patent/DE69535653T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/02002—Dihydropyrimidinase (3.5.2.2), i.e. hydantoinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69535653T 1994-12-28 1995-12-26 Verfahren zur Herstellung einer D-N-Carbamoyl-alpha-Aminosäure Expired - Fee Related DE69535653T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32686594 1994-12-28
JP32686594 1994-12-28

Publications (2)

Publication Number Publication Date
DE69535653D1 true DE69535653D1 (de) 2008-01-03
DE69535653T2 DE69535653T2 (de) 2008-11-13

Family

ID=18192596

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69535653T Expired - Fee Related DE69535653T2 (de) 1994-12-28 1995-12-26 Verfahren zur Herstellung einer D-N-Carbamoyl-alpha-Aminosäure
DE69535398T Expired - Fee Related DE69535398T2 (de) 1994-12-28 1995-12-26 Verfahren zur herstellung einer d-n-carbamoyl-alpha-aminosäure

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69535398T Expired - Fee Related DE69535398T2 (de) 1994-12-28 1995-12-26 Verfahren zur herstellung einer d-n-carbamoyl-alpha-aminosäure

Country Status (6)

Country Link
EP (3) EP0801131B1 (de)
KR (1) KR100244066B1 (de)
CN (3) CN1082090C (de)
DE (2) DE69535653T2 (de)
ES (1) ES2281075T3 (de)
WO (1) WO1996020275A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524837B1 (en) * 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids
IL157937A0 (en) * 2001-04-03 2004-03-28 Bristol Myers Squibb Co D-hydantoinase, nucleic acid encoding the same, expression vectors including said nucleic acid and host cells expressing the same
JP4561010B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法
JP4561009B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法
CA2486350A1 (en) 2002-06-05 2003-12-24 Kaneka Corporation Process for producing optically active .alpha.-methylcysteine derivative
EP1541692A1 (de) * 2002-09-06 2005-06-15 Kaneka Corporation VERFAHREN ZUR HERSTELLUNG EINES L-a-METHYLCYSTEIN-DERIVATS
US20060172393A1 (en) * 2003-01-10 2006-08-03 Kaneka Corporation Process for producing optically active alpha -methylcysteine derivative
WO2006103995A1 (ja) * 2005-03-25 2006-10-05 Kaneka Corporation 光学活性α－アミノ酸誘導体の製造方法
WO2007040272A1 (ja) * 2005-10-06 2007-04-12 Kaneka Corporation Ｄ－（４－アミノメチル）フェニルアラニン誘導体の製造法
EP2255780A1 (de) * 2008-03-12 2010-12-01 Shiseido Company, Ltd. Parakeratosehemmer, porenverkleinerungsmittel bzw. mittel zur vermeidung oder verbesserung von rauer haut und zusammensetzung zur anwendung auf der haut damit

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211840A (en) * 1977-06-08 1980-07-08 Ajinomoto Company, Incorporated Method for producing D-α-amino acid
DE3535987A1 (de) * 1985-10-09 1987-04-23 Basf Ag Verfahren zur herstellung von meophilen mikroorganismen, die eine bei hoeherer temperatur aktive d-hydantoinase enthalten
JP2679031B2 (ja) * 1986-07-16 1997-11-19 味の素株式会社 アミノ酸の製造法及びアミノ酸生産菌
ES2058121T3 (es) * 1986-09-17 1994-11-01 Beecham Group Plc Preparacion enzimatica inmovilizada y su uso.
JP2728465B2 (ja) * 1988-10-28 1998-03-18 協和醗酵工業株式会社 Ｌ−ホモフエニルアラニンの製造法
JPH02276586A (ja) * 1989-04-19 1990-11-13 Bio-Le Kk Ｄ‐ホモフエニルアラニンの製造法
JPH03133386A (ja) * 1989-10-19 1991-06-06 Kanegafuchi Chem Ind Co Ltd 固定化微生物を用いた酵素反応方法
US5565344A (en) * 1990-12-07 1996-10-15 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for production of D-α-amino acids
JPH04325093A (ja) * 1991-04-23 1992-11-13 Nippon Soda Co Ltd 耐熱性ヒダントイナーゼ、及びそれをコードする遺伝子
SG54305A1 (en) * 1991-06-12 1998-11-16 Kanegafuchi Chemical Ind Immobilized enzyme preparation and process for producing d--g(a)-amino acid
ES2042409B1 (es) * 1992-04-10 1994-06-01 Control & Gestion Instr Procedimiento para la preparacion de d-aminoacidos o derivados de d-aminoacidos.
JP3510625B2 (ja) * 1992-06-30 2004-03-29 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー Ｄ−ｎ−カルバモイル−アミノ酸アミドヒドロラーゼおよびヒダントイナーゼ
DE4328829A1 (de) * 1993-08-27 1995-03-02 Boehringer Mannheim Gmbh Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
IT1274167B (it) * 1994-04-15 1997-07-15 Eniricerche Spa Procedimento per la produzione di d- -amminoacidi
DE69531725T2 (de) * 1994-06-24 2004-07-08 Kanegafuchi Kagaku Kogyo K.K. Verfahren zur herstellung von d-aminosäure durch eine zusammengesetzte immobilisierte enzymenverbindung

Also Published As

Publication number Publication date
DE69535653T2 (de) 2008-11-13
KR987001034A (ko) 1998-04-30
EP0801131A1 (de) 1997-10-15
CN1916164A (zh) 2007-02-21
EP0801131A4 (de) 2000-03-22
DE69535398D1 (de) 2007-04-05
CN1502701A (zh) 2004-06-09
DE69535398T2 (de) 2007-10-31
CN1082090C (zh) 2002-04-03
CN1171812A (zh) 1998-01-28
CN100406553C (zh) 2008-07-30
EP1616946A1 (de) 2006-01-18
EP1616945A1 (de) 2006-01-18
EP0801131B1 (de) 2007-02-21
KR100244066B1 (ko) 2000-02-01
EP1616945B1 (de) 2007-11-21
WO1996020275A1 (fr) 1996-07-04
ES2281075T3 (es) 2007-09-16
CN100516197C (zh) 2009-07-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee