DE69535328D1 - In-vitro wachstum von langerhans'schen inseln und ihre verwendungen - Google Patents

In-vitro wachstum von langerhans'schen inseln und ihre verwendungen

Info

Publication number
DE69535328D1
DE69535328D1 DE69535328T DE69535328T DE69535328D1 DE 69535328 D1 DE69535328 D1 DE 69535328D1 DE 69535328 T DE69535328 T DE 69535328T DE 69535328 T DE69535328 T DE 69535328T DE 69535328 D1 DE69535328 D1 DE 69535328D1
Authority
DE
Germany
Prior art keywords
schen
langerhans
islands
vitro growth
grow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69535328T
Other languages
English (en)
Other versions
DE69535328T2 (de
Inventor
Ammon B Peck
Janet G Cornelius
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida
University of Florida Research Foundation Inc
Original Assignee
University of Florida
University of Florida Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Florida, University of Florida Research Foundation Inc filed Critical University of Florida
Application granted granted Critical
Publication of DE69535328D1 publication Critical patent/DE69535328D1/de
Publication of DE69535328T2 publication Critical patent/DE69535328T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
DE69535328T 1994-04-28 1995-04-28 In-vitro wachstum von langerhans'schen inseln und ihre verwendungen Expired - Fee Related DE69535328T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US234071 1994-04-28
US08/234,071 US5834308A (en) 1994-04-28 1994-04-28 In vitro growth of functional islets of Langerhans
PCT/US1995/005303 WO1995029988A1 (en) 1994-04-28 1995-04-28 In vitro growth of functional islets of langerhans and in vivo uses thereof

Publications (2)

Publication Number Publication Date
DE69535328D1 true DE69535328D1 (de) 2007-01-18
DE69535328T2 DE69535328T2 (de) 2007-07-05

Family

ID=22879774

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535328T Expired - Fee Related DE69535328T2 (de) 1994-04-28 1995-04-28 In-vitro wachstum von langerhans'schen inseln und ihre verwendungen

Country Status (10)

Country Link
US (1) US5834308A (de)
EP (1) EP0758376B1 (de)
JP (1) JP3621106B2 (de)
KR (1) KR100374976B1 (de)
AT (1) ATE347585T1 (de)
AU (1) AU709165B2 (de)
CA (1) CA2188648A1 (de)
DE (1) DE69535328T2 (de)
ES (1) ES2276392T3 (de)
WO (1) WO1995029988A1 (de)

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DE10026480A1 (de) * 2000-05-29 2001-12-13 Augustinus Bader Verfahren zur Herstellung eines empfängerspezifischen Gewebe-Transplantats oder -Implantats
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US20060122104A1 (en) * 2002-05-28 2006-06-08 Presnell Sharon C Methods for in vitro expansion and transdifferentiation of human pancreatic acinar cells into insulin-producing cells
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US7939322B2 (en) 2008-04-24 2011-05-10 Centocor Ortho Biotech Inc. Cells expressing pluripotency markers and expressing markers characteristic of the definitive endoderm
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CA2729121C (en) 2008-06-30 2019-04-09 Centocor Ortho Biotech Inc. Differentiation of pluripotent stem cells
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JP5908394B2 (ja) 2009-03-26 2016-04-26 デピュイ・シンセス・プロダクツ・インコーポレイテッド アルツハイマー病の療法としてのヒト臍帯組織細胞
KR20170118969A (ko) 2009-07-20 2017-10-25 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
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Also Published As

Publication number Publication date
DE69535328T2 (de) 2007-07-05
EP0758376A1 (de) 1997-02-19
ATE347585T1 (de) 2006-12-15
AU2369595A (en) 1995-11-29
CA2188648A1 (en) 1995-11-09
JPH09512440A (ja) 1997-12-16
US5834308A (en) 1998-11-10
WO1995029988A1 (en) 1995-11-09
AU709165B2 (en) 1999-08-26
EP0758376B1 (de) 2006-12-06
KR100374976B1 (ko) 2003-12-31
ES2276392T3 (es) 2007-06-16
JP3621106B2 (ja) 2005-02-16
MX9604845A (es) 1998-05-31

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