DE60009956D1 - Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium - Google Patents

Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium

Info

Publication number
DE60009956D1
DE60009956D1 DE60009956T DE60009956T DE60009956D1 DE 60009956 D1 DE60009956 D1 DE 60009956D1 DE 60009956 T DE60009956 T DE 60009956T DE 60009956 T DE60009956 T DE 60009956T DE 60009956 D1 DE60009956 D1 DE 60009956D1
Authority
DE
Germany
Prior art keywords
culture medium
cell culture
growth factors
containing cell
glutamine containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60009956T
Other languages
English (en)
Other versions
DE60009956T2 (de
Inventor
Bruijn Dick De
Johannes Tibbe
Silva Madureira Mendes Clau Da
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OctoPlus Sciences BV
Original Assignee
Iso Tis NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iso Tis NV filed Critical Iso Tis NV
Application granted granted Critical
Publication of DE60009956D1 publication Critical patent/DE60009956D1/de
Publication of DE60009956T2 publication Critical patent/DE60009956T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/40Nucleotides, nucleosides, bases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/42Organic phosphate, e.g. beta glycerophosphate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE60009956T 1999-12-28 2000-12-27 Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium Expired - Fee Related DE60009956T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99204569 1999-12-28
EP99204569 1999-12-28
PCT/NL2000/000958 WO2001048147A1 (en) 1999-12-28 2000-12-27 Cell culture medium containing growth factors and l-glutamine

Publications (2)

Publication Number Publication Date
DE60009956D1 true DE60009956D1 (de) 2004-05-19
DE60009956T2 DE60009956T2 (de) 2005-04-28

Family

ID=8241117

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60009956T Expired - Fee Related DE60009956T2 (de) 1999-12-28 2000-12-27 Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium

Country Status (11)

Country Link
US (1) US6838284B2 (de)
EP (1) EP1242578B1 (de)
JP (1) JP2003518378A (de)
AT (1) ATE264385T1 (de)
AU (1) AU780653B2 (de)
CA (1) CA2395271A1 (de)
DE (1) DE60009956T2 (de)
DK (1) DK1242578T3 (de)
ES (1) ES2217031T3 (de)
TR (1) TR200401091T4 (de)
WO (1) WO2001048147A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003052360A (ja) * 2001-08-20 2003-02-25 Japan Science & Technology Corp 基底膜細胞外基質を用いた間葉系幹細胞の培養方法
DE102004041354A1 (de) * 2004-08-25 2006-03-30 Buck, Alfred Implantat für den chirurgischen Einsatz bei Menschen oder Wirbeltieren
US20060166305A1 (en) * 2005-01-27 2006-07-27 Genetix Limited Animal cell confluence detection method and apparatus
DE102005017000B4 (de) * 2005-04-13 2007-10-04 Technische Universität Dresden Verfahren zur Herstellung eines Gewebetransplantatkonstruktes zur Rekonstruktion eines menschlichen oder tierischen Organs
WO2006121043A1 (ja) 2005-05-09 2006-11-16 Olympus Corporation 間葉系幹細胞の培養方法および生体組織補填体の製造方法
EP1915169A2 (de) 2005-07-12 2008-04-30 Renovo Limited Pharmazeutische zusammensetzungen mit einem tgf-beta superfamilien-mitglied
US20100273231A1 (en) * 2005-09-20 2010-10-28 Andreadis Stelios T Multipotent mesenchymal stem cells from human hair follicles
RU2009141965A (ru) 2007-04-16 2011-05-27 Момента Фармасьютикалз, Инк. (Us) Определенные продукты гликопротеина и способы их производства
AU2008298816B2 (en) 2007-09-11 2013-09-26 Sapporo Medical University Cell growth method and pharmaceutical preparation for tissue repair and regeneration
ES2533074T3 (es) 2010-04-26 2015-04-07 Novartis Ag Medio de cultivo celular mejorado
CN102869762B (zh) * 2010-05-05 2015-09-02 泰尔茂比司特公司 重新接种中空纤维生物反应器系统中生长的贴壁细胞的方法
US9677042B2 (en) 2010-10-08 2017-06-13 Terumo Bct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
US9617506B2 (en) 2013-11-16 2017-04-11 Terumo Bct, Inc. Expanding cells in a bioreactor
EP3613841B1 (de) 2014-03-25 2022-04-20 Terumo BCT, Inc. Passives ersetzen von medien
EP3198006B1 (de) 2014-09-26 2021-03-24 Terumo BCT, Inc. Geplante fütterung
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
CN106190962B (zh) * 2016-07-27 2019-11-29 华中农业大学 一种猪骨骼肌卫星细胞的培养基pm+及其应用
EP3485280A1 (de) 2016-08-12 2019-05-22 Lonza Ltd Proteomische analyse von wirtszellenproteinen
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656842A1 (de) 2017-03-31 2020-05-27 Terumo BCT, Inc. Zellexpansion
WO2019004293A1 (ja) * 2017-06-27 2019-01-03 味の素株式会社 リボフラビン誘導体含有培地
CN111512161A (zh) 2017-12-05 2020-08-07 隆萨有限公司 分析托酚酮的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811094A (en) * 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5858783A (en) * 1993-05-25 1999-01-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Production of normal mammalian organ culture using a medium containing mem-alpha, leibovitz L-15, glucose galactose fructose
US5830682A (en) * 1994-09-09 1998-11-03 Zymogenetics Preparation of immortalized cells
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US5733541A (en) * 1995-04-21 1998-03-31 The Regent Of The University Of Michigan Hematopoietic cells: compositions and methods
JP3781433B2 (ja) * 1995-11-16 2006-05-31 ケース ウエスターン リザーブ ユニバーシティ ヒト間葉幹細胞の試験管内軟骨形成誘導
IT1282207B1 (it) * 1995-11-20 1998-03-16 Fidia Advanced Biopolymers Srl Sistemi di coltura di cellule staminali di midollo osseo umano in matrici tridimensionali costituiti da esteri dell'acido ialuronico
US6271436B1 (en) * 1996-10-11 2001-08-07 The Texas A & M University System Cells and methods for the generation of transgenic pigs
WO1998041611A1 (en) * 1997-03-20 1998-09-24 Regents Of The University Of Minnesota Process for the continuous culture of cells
US6537782B1 (en) * 1998-06-01 2003-03-25 Chugai Seiyaku Kabushiki Kaisha Media for culturing animal cells and process for producing protein by using the same
RU2272839C2 (ru) * 1998-11-09 2006-03-27 Консорцио Пер Ла Джестионе Дель Чентро Ди Биотекнолоджие Аванцате Бессывороточная среда для культуры клеток, используемых для реконструкции костных и хрящевых сегментов (варианты)

Also Published As

Publication number Publication date
ATE264385T1 (de) 2004-04-15
EP1242578B1 (de) 2004-04-14
WO2001048147A9 (en) 2002-09-12
AU780653B2 (en) 2005-04-07
EP1242578A1 (de) 2002-09-25
AU3246101A (en) 2001-07-09
JP2003518378A (ja) 2003-06-10
TR200401091T4 (tr) 2004-06-21
DE60009956T2 (de) 2005-04-28
ES2217031T3 (es) 2004-11-01
CA2395271A1 (en) 2001-07-05
WO2001048147A1 (en) 2001-07-05
US20030017588A1 (en) 2003-01-23
US6838284B2 (en) 2005-01-04
DK1242578T3 (da) 2004-07-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: OCTOPLUS SCIENCES B.V., LEIDEN, NL

8339 Ceased/non-payment of the annual fee