DE69530409T2 - Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat - Google Patents

Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat

Info

Publication number
DE69530409T2
DE69530409T2 DE69530409T DE69530409T DE69530409T2 DE 69530409 T2 DE69530409 T2 DE 69530409T2 DE 69530409 T DE69530409 T DE 69530409T DE 69530409 T DE69530409 T DE 69530409T DE 69530409 T2 DE69530409 T2 DE 69530409T2
Authority
DE
Germany
Prior art keywords
cells
epithelic
transplant
biomaterial containing
biomaterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69530409T
Other languages
English (en)
Other versions
DE69530409D1 (de
Inventor
Nikolaos Dimoudis
Anton Hartinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Switch Biotech AG
Original Assignee
Switch Biotech AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4438015A external-priority patent/DE4438015A1/de
Application filed by Switch Biotech AG filed Critical Switch Biotech AG
Priority to DE69530409T priority Critical patent/DE69530409T2/de
Application granted granted Critical
Publication of DE69530409D1 publication Critical patent/DE69530409D1/de
Publication of DE69530409T2 publication Critical patent/DE69530409T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/78—Cellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE69530409T 1994-10-25 1995-10-24 Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat Expired - Fee Related DE69530409T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE69530409T DE69530409T2 (de) 1994-10-25 1995-10-24 Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4438015A DE4438015A1 (de) 1994-10-25 1994-10-25 Epithelzellenhaltiges Biomaterial und dessen Verwendung als Transplantat
US45270195A 1995-05-30 1995-05-30
PCT/EP1995/004164 WO1996012510A1 (en) 1994-10-25 1995-10-24 Biomaterial containing epithelial cells and use thereof as a transplant
DE69530409T DE69530409T2 (de) 1994-10-25 1995-10-24 Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat

Publications (2)

Publication Number Publication Date
DE69530409D1 DE69530409D1 (de) 2003-05-22
DE69530409T2 true DE69530409T2 (de) 2003-12-24

Family

ID=25941338

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69530409T Expired - Fee Related DE69530409T2 (de) 1994-10-25 1995-10-24 Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat

Country Status (7)

Country Link
EP (1) EP0788381B1 (de)
JP (1) JPH09511673A (de)
AT (1) ATE237373T1 (de)
AU (1) AU3806695A (de)
DE (1) DE69530409T2 (de)
IL (1) IL115728A0 (de)
WO (1) WO1996012510A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4264597A (en) * 1996-09-24 1998-04-17 Brigham And Women's Hospital Cultured cell-seeded fibrous lattice for tissue replacement
US5972332A (en) 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
US20020037566A1 (en) * 1997-04-16 2002-03-28 Rees Riley S. Cell-coated supports
AU1335699A (en) * 1997-10-25 1999-05-17 Boehringer Mannheim Gmbh Modified microcarriers and their use in cell cryoconservation
US6660301B1 (en) * 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
JP3043727B1 (ja) * 1998-11-26 2000-05-22 実 上田 粘膜上皮細胞シート
DE19937102A1 (de) * 1999-08-06 2001-02-15 Universitaetsklinikum Freiburg Gewebeersatz und Verfahren zu seiner Herstellung
US6436424B1 (en) 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
EP1656957B1 (de) * 2000-03-20 2015-06-03 Biosphere Medical, Inc. Injizierbare Mikrosphären zur Gewebekonstruktion
US7338657B2 (en) 2001-03-15 2008-03-04 Biosphere Medical, Inc. Injectable microspheres for tissue construction
WO2001070289A2 (en) * 2000-03-20 2001-09-27 Biosphere Medical, Inc. Injectable and swellable microspheres for tissue bulking
DE60120127T2 (de) * 2000-03-20 2007-01-04 Biosphere Medical, Inc., Rockland Injizierbare mikrokügelchen für den gewebeaufbau
FR2807765B1 (fr) * 2000-04-18 2004-12-31 Cell Culture Ct Comp Procede de culture de cellules, amas cellulaires obtenus par ces procedes et utilisation de ceux-ci
JP3728750B2 (ja) 2001-11-22 2005-12-21 ニプロ株式会社 培養皮膚及びその製造方法
US20050019310A1 (en) * 2001-12-21 2005-01-27 Isaacs Richard John Method for culturing and expansion of mammalian undifferentiated epidermal kerainocytes exhibiting stem cell characteristics
EP2351779B1 (de) 2010-01-27 2019-04-24 Biosphere Medical, Inc. Mikrokügelchen und Verfahren zur Herstellung der Mikrokügelchen
CA3071304C (en) 2010-05-25 2023-09-05 Cook Biotech Incorporated Methods, substrates, and systems useful for cell seeding of medical grafts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE445116B (sv) * 1979-09-12 1986-06-02 Pharmacia Fine Chemicals Ab Sett att odla celler pa mikroberare med fibronektinytskikt
DK210989D0 (da) * 1989-05-01 1989-05-01 Danochemo As Microcarriers fremstillet ved sprayteknik
DE4038397A1 (de) * 1990-12-01 1992-06-04 Boehringer Ingelheim Kg Mikrocarrier fuer verankerungsbeduerftige zellen
RU2010028C1 (ru) * 1991-06-28 1994-03-30 Васильев Андрей Валентинович Способ восстановления кожного покрова у тяжелообожженных
GB9210574D0 (en) * 1992-05-18 1992-07-01 Ca Nat Research Council Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications

Also Published As

Publication number Publication date
IL115728A0 (en) 1996-01-19
DE69530409D1 (de) 2003-05-22
AU3806695A (en) 1996-05-15
ATE237373T1 (de) 2003-05-15
WO1996012510A1 (en) 1996-05-02
JPH09511673A (ja) 1997-11-25
EP0788381B1 (de) 2003-04-16
EP0788381A1 (de) 1997-08-13

Similar Documents

Publication Publication Date Title
ATE237373T1 (de) Epithelzellen enthaltendes biomaterial und ihre verwendung als transplantat
ATE347585T1 (de) In-vitro wachstum von langerhans'schen inseln und ihre verwendungen
NZ288467A (en) In vitro method for culturing cartilage tissue by culturing stromal cells in the presence of growth factors
FI834623A0 (fi) Foer medicinska aendamaol avsedd vaetskeimpregnerad saordyna
DE60018044D1 (de) Neue biomaterialien
CA2244659A1 (en) Biological reactor for the cultivation of cells
DE69231485T2 (de) Verwendung von porösem Calciumcarbonat als Trägermaterial für in vitro Zellkulturen.
ATE88191T1 (de) Polypeptide mit kollagen typ iv aktivitaet.
BR9007643A (pt) Metodo para se conseguir a epitelizacao de lentes sinteticas
DE69626290T2 (de) Hemmung von gefässverengungen nach eingriffen an den gefässen
DE68911178D1 (de) Klinische Entwicklungen mit Amnionzellen.
EP0441639A3 (en) Instrument for the application of controlled mechanical loads to tissues in sterile culture
ATE84796T1 (de) Polypeptide mit einer laminin-wirksamkeit.
DE69631972D1 (de) Proliferationsinhibitor von endothellzellen und dessen verwendung
ATE227995T1 (de) Verwendung von pseudopterosin zur förderung der wundheilung
DE69110906D1 (de) Verwendung von Wirtszellphospholipiden zur Hemmung bakterieller Besiedlung.
ATE197961T1 (de) Stromale zellinien aus menschlichem knochenmark und ihre verwendung
DE3583227D1 (de) Isolierung und kultur von faktor viii:c produzierenden adrenalmedullarischen endothelialen zellen.
DE69100748T2 (de) Kühllagerung gezüchteter epithelschichten.
PL285546A1 (en) Biological culture medium for cell cultures and method of culturing human keratocytes as well as proteinous concentrate

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee