DE3582639D1 - In vitro-zellkultur-system und verfahren. - Google Patents

In vitro-zellkultur-system und verfahren.

Info

Publication number
DE3582639D1
DE3582639D1 DE8585111548T DE3582639T DE3582639D1 DE 3582639 D1 DE3582639 D1 DE 3582639D1 DE 8585111548 T DE8585111548 T DE 8585111548T DE 3582639 T DE3582639 T DE 3582639T DE 3582639 D1 DE3582639 D1 DE 3582639D1
Authority
DE
Germany
Prior art keywords
cells
cell culture
vitro cell
calcium
porous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585111548T
Other languages
English (en)
Inventor
Herman S Cheung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical College of Wisconsin Research Foundation Inc
Original Assignee
Medical College of Wisconsin Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical College of Wisconsin Research Foundation Inc filed Critical Medical College of Wisconsin Research Foundation Inc
Application granted granted Critical
Publication of DE3582639D1 publication Critical patent/DE3582639D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/18—Calcium salts, e.g. apatite, Mineral components from bones, teeth, shells
DE8585111548T 1984-09-14 1985-09-12 In vitro-zellkultur-system und verfahren. Expired - Fee Related DE3582639D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/651,392 US4757017A (en) 1984-09-14 1984-09-14 In vitro cell culture system

Publications (1)

Publication Number Publication Date
DE3582639D1 true DE3582639D1 (de) 1991-05-29

Family

ID=24612692

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585111548T Expired - Fee Related DE3582639D1 (de) 1984-09-14 1985-09-12 In vitro-zellkultur-system und verfahren.

Country Status (6)

Country Link
US (1) US4757017A (de)
EP (1) EP0175286B1 (de)
JP (1) JPS61108386A (de)
AT (1) ATE62932T1 (de)
CA (1) CA1247542A (de)
DE (1) DE3582639D1 (de)

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JPS61235752A (ja) * 1985-04-11 1986-10-21 Asahi Optical Co Ltd 細胞分離材、分離器および分離方法
US5736372A (en) * 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
US5041138A (en) * 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US6309635B1 (en) 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
US5804178A (en) * 1986-11-20 1998-09-08 Massachusetts Institute Of Technology Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue
GB8721018D0 (en) * 1987-09-07 1987-10-14 Alcan Int Ltd Porous inorganic membrane support
US5496722A (en) * 1988-06-30 1996-03-05 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for producing non-neoplastic, three dimensional, mammalian tissue and cell aggregates under microgravity culture conditions and the products produced therefrom
US5155034A (en) * 1988-06-30 1992-10-13 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Three-dimensional cell to tissue assembly process
US5162225A (en) * 1989-03-17 1992-11-10 The Dow Chemical Company Growth of cells in hollow fibers in an agitated vessel
US5443832A (en) * 1990-04-16 1995-08-22 Institut Swisse De Recherches Experimentales Sur Le Cancer Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
US5242806A (en) * 1990-05-07 1993-09-07 Baxter Diagnostics Inc. Method for conducting the cytotoxicity assays on tumor cells
US5262320A (en) * 1990-06-18 1993-11-16 Massachusetts Institute Of Technology Cell-culturing apparatus and method employing a macroporous support
JPH04141084A (ja) * 1990-10-01 1992-05-14 Mitsubishi Materials Corp 無血清細胞培養担体
JPH04278082A (ja) * 1991-03-02 1992-10-02 Mitsubishi Materials Corp 無血清細胞培養担体
FR2679250B1 (fr) * 1991-07-19 1995-07-13 Inoteb Utilisation de carbonate de calcium poreux comme materiau support de culture in vitro de cellules eucaryotes.
US5326357A (en) * 1992-03-18 1994-07-05 Mount Sinai Hospital Corporation Reconstituted cartridge tissue
IL103919A0 (en) * 1992-11-29 1993-04-04 Yeda Res & Dev Carriers for cell culture
US5858783A (en) * 1993-05-25 1999-01-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Production of normal mammalian organ culture using a medium containing mem-alpha, leibovitz L-15, glucose galactose fructose
IL110195A (en) * 1994-07-03 2003-10-31 David Danon Method and system for cultivating macrophages
US6146890A (en) * 1994-07-03 2000-11-14 Danon; David Method and system for cultivating macrophages
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5618718A (en) * 1994-12-30 1997-04-08 Universite Laval Production of a contractile smooth muscle
US6123727A (en) 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
GB9515327D0 (en) * 1995-07-26 1995-09-20 Univ London Site-directed bone formation
ES2156289T3 (es) 1995-08-31 2001-06-16 Ashby Scient Ltd Aparato y metodos para cultivar material biologico.
GB2304732A (en) * 1995-08-31 1997-03-26 Ashby Scient Ltd Culture vessel comprising pitted growth substrate
AU7274696A (en) 1995-11-06 1997-05-29 Mount Sinai Hospital Corporation Reconstituted mineralized cartilage tissue
US20020111695A1 (en) * 1995-11-06 2002-08-15 Mount Sinai Hospital Corporation Reconstituted mineralized cartilage tissue
DE69840069D1 (de) 1997-04-01 2008-11-13 Cap Biotechnology Inc Kalziumphosphat-mikroträger und -mikrokugeln
US6514522B2 (en) 1998-04-08 2003-02-04 Chondros, Inc. Polymer constructs
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
ES2327026T3 (es) 1999-07-08 2009-10-23 Cap Biotechnology, Inc. Estructuras que contienen calcio y procedimientos de fabricacion y uso de las mismas.
WO2001029189A2 (en) * 1999-10-15 2001-04-26 Mount Sinai Hospital Synthetic substrate for tissue formation
JP2005516972A (ja) * 2002-01-22 2005-06-09 ファイザー・インク 血栓疾患の治療のためのｔａｆｉ−ａ阻害剤として使用される３−（イミダゾリル）−２−アミノプロピオン酸
US7642092B2 (en) * 2003-03-03 2010-01-05 Technion Research & Development Foundation Ltd. Cultured cartilage/bone cells/tissue, method of generating same and uses thereof
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
JP2006034200A (ja) * 2004-07-28 2006-02-09 Pentax Corp 細胞培養担体、細胞培養担体の製造方法および細胞培養方法
US7837740B2 (en) * 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
JP2009508596A (ja) 2005-09-19 2009-03-05 ヒストジェニックス コーポレイション 細胞支持基材及びその調製方法
EP2264149A1 (de) * 2005-11-10 2010-12-22 Carticure Ltd. Verfahren zur nichtautologen Knorpelregeneration
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
WO2009111069A1 (en) * 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
WO2017125918A1 (en) 2016-01-18 2017-07-27 Amorphical Ltd. Stabilized amorphous calcium carbonate for treatment of neurological, muscular and infertility diseases or conditions
CA3011664A1 (en) * 2016-01-18 2017-07-27 Amorphical Ltd. Stabilized amorphous calcium carbonate as a supplement for cell culture media
CN106434538A (zh) * 2016-09-29 2017-02-22 广州赛莱拉干细胞科技股份有限公司 软骨细胞的三维培养方法、制得的软骨组织与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2053565A5 (de) * 1969-07-09 1971-04-16 Pasteur Institut
GB1586364A (en) * 1976-06-17 1981-03-18 Atomic Energy Authority Uk Porous inorganic materials
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof

Also Published As

Publication number Publication date
CA1247542A (en) 1988-12-28
ATE62932T1 (de) 1991-05-15
JPS61108386A (ja) 1986-05-27
EP0175286A2 (de) 1986-03-26
EP0175286A3 (en) 1988-07-27
EP0175286B1 (de) 1991-04-24
US4757017A (en) 1988-07-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee