DE69533905D1 - Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung - Google Patents

Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung

Info

Publication number
DE69533905D1
DE69533905D1 DE69533905T DE69533905T DE69533905D1 DE 69533905 D1 DE69533905 D1 DE 69533905D1 DE 69533905 T DE69533905 T DE 69533905T DE 69533905 T DE69533905 T DE 69533905T DE 69533905 D1 DE69533905 D1 DE 69533905D1
Authority
DE
Germany
Prior art keywords
production
application
binding protein
interferon alpha
beta binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69533905T
Other languages
English (en)
Other versions
DE69533905T2 (de
Inventor
Batya Cohen
Daniela Novick
Menachem Rubinstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of DE69533905D1 publication Critical patent/DE69533905D1/de
Publication of DE69533905T2 publication Critical patent/DE69533905T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69533905T 1994-02-07 1995-02-06 Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung Expired - Lifetime DE69533905T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL10858494 1994-02-07
IL108584A IL108584A (en) 1994-02-07 1994-02-07 Cloning of the interferon-binding protein ALPHA / BETA

Publications (2)

Publication Number Publication Date
DE69533905D1 true DE69533905D1 (de) 2005-02-10
DE69533905T2 DE69533905T2 (de) 2005-12-29

Family

ID=11065792

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533905T Expired - Lifetime DE69533905T2 (de) 1994-02-07 1995-02-06 Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung

Country Status (17)

Country Link
EP (1) EP0676413B9 (de)
JP (2) JP3670045B2 (de)
KR (1) KR100382628B1 (de)
CN (1) CN1286976C (de)
AT (1) ATE286509T1 (de)
AU (1) AU688430B2 (de)
CA (1) CA2141747C (de)
DE (1) DE69533905T2 (de)
DK (1) DK0676413T3 (de)
ES (1) ES2236696T3 (de)
FI (1) FI118084B (de)
IL (1) IL108584A (de)
NO (1) NO318912B1 (de)
PT (1) PT676413E (de)
RU (4) RU2232811C2 (de)
UA (1) UA46694C2 (de)
ZA (1) ZA95968B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL118096A0 (en) * 1996-05-01 1996-09-12 Yeda Res & Dev Antibodies against interferon alpha/beta receptor
US7087726B2 (en) * 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
CN1405181A (zh) * 2001-08-10 2003-03-26 中国人民解放军军事医学科学院生物工程研究所 血清白蛋白与干扰素的融合蛋白
EP1893646A2 (de) * 2005-06-22 2008-03-05 Genentech, Inc. Verfahren und zusammensetzungen für ifnar2-targeting
JP5104622B2 (ja) * 2008-07-29 2012-12-19 Ｊｎｃ株式会社 磁性粒子を用いた測定対象物質の濃度測定法
US9492562B2 (en) * 2012-01-20 2016-11-15 Vib Vzw Targeted human-interferon fusion proteins
MX2018013222A (es) * 2016-04-29 2019-04-22 Pfizer Anticuerpos de interferon beta y usos de los mismos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2653445B1 (fr) * 1989-10-20 1994-07-29 Centre Nat Rech Scient Fragment d'adnc codant pour le gene du recepteur de l'interferon alpha et procede de preparation d'une proteine correspondante.
KR0172969B1 (ko) * 1991-04-17 1999-02-01 삐에르 까스뗄 인터페론 알파 및 베타에 대해 높은 친화력을 갖는 수용성 폴리펩티드
IL106591A (en) * 1992-09-03 2008-03-20 Yeda Res & Dev Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it

Also Published As

Publication number Publication date
RU2336279C2 (ru) 2008-10-20
CN1286976C (zh) 2006-11-29
NO318912B1 (no) 2005-05-23
RU2004106773A (ru) 2005-08-10
FI950516A0 (fi) 1995-02-06
FI950516A (fi) 1995-08-08
IL108584A0 (en) 1994-05-30
CN1109505A (zh) 1995-10-04
DE69533905T2 (de) 2005-12-29
AU1141695A (en) 1995-08-17
EP0676413A2 (de) 1995-10-11
CA2141747C (en) 2012-05-01
RU2004106775A (ru) 2005-08-10
KR950032620A (ko) 1995-12-22
RU2362781C2 (ru) 2009-07-27
AU688430B2 (en) 1998-03-12
NO950420L (no) 1995-08-08
EP0676413B9 (de) 2005-05-18
ZA95968B (en) 1995-10-10
RU2363705C2 (ru) 2009-08-10
NO950420D0 (no) 1995-02-06
CA2141747A1 (en) 1995-08-08
RU2004106774A (ru) 2005-08-10
JPH07298886A (ja) 1995-11-14
IL108584A (en) 2008-03-20
KR100382628B1 (ko) 2004-02-25
PT676413E (pt) 2005-05-31
DK0676413T3 (da) 2005-05-09
JP2005200422A (ja) 2005-07-28
EP0676413B1 (de) 2005-01-05
JP3670045B2 (ja) 2005-07-13
UA46694C2 (uk) 2002-06-17
FI118084B (fi) 2007-06-29
EP0676413A3 (de) 1996-04-03
ATE286509T1 (de) 2005-01-15
ES2236696T3 (es) 2005-07-16
RU2232811C2 (ru) 2004-07-20

Similar Documents

Publication Publication Date Title
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
DE69131580D1 (de) GDF-1 und UOG1 Proteine
DK1394179T3 (da) Fremgangsmåde til fremstilling af erythropoietin fri for animalske proteiner
SE8105657L (sv) Mikrobiell framstellning av humanfibroblastinterferon
DE69535031D1 (de) Selektive Acylierung von Epsilon-Aminogruppen in Insulin
DE69514342T2 (de) Modifizierte polypeptide mit erhoehter biologischer aktivitaet
DE3585953D1 (de) Dna-fragmente, expressionsvektoren, proteine, wirte und verfahren zur herstellung der proteine.
EE200000152A (et) Aminoterminaalselt kärbitud MCP-2 vormid, DNA molekulid, ekspressioonivektor, peremeesrakk, rekombinantne meetod proteiini valmistamiseks, proteiini kasutamine ning farmatseutiline kompositsioon
DE69737651D1 (de) Cortistatin: neuropeptide, zusammensetzungen und methoden
DE69533905D1 (de) Interferon alpha/beta bindendes Protein, seine Herstellung und Anwendung
DK1082423T3 (da) Cyclin E2-gener og -proteiner
DE3576361D1 (de) Rekombinante dna, damit transformierter mikroorganismus, und verfahren zur herstellung von menschlicher cu-zn superoxiddismutase unter verwendung des transformierten mikroorganismus.
FI970097A (fi) Proteiinit, jotka ovat peräisin nisäkkäiden maksasta ja niiden käyttö onkologiassa
ATE236983T1 (de) Durch zelldichte stimulierte protein-tyrosin- phosphatasen
ATE193324T1 (de) Rekombinante herstellung von laktoperoxidase
ZA979390B (en) Polypeptides comprising domains of the GAX protein which are involved in the repression of transcription and/or which interact with other proteins, corresponding nucleic acids and their uses.
DE69929638D1 (de) Plasmide, deren Konstruktion und Anwendung zur Herstellung von Interleukin-4 und dessen Muteine
ATE130872T1 (de) Ancrod ähnliche proteine, ihre herstellung und verwendung.
ATE49964T1 (de) Benzodioxepane, verfahren zur herstellung und verwendung als heilmittel.
DE59404726D1 (de) Angiogenin und/oder alpha1-microglobulin und/oder komplementfaktor d zur begrenzung der sekretion von proteinen
ATE105335T1 (de) Traegergebundene rekombinante proteine, verfahren zur herstellung und verwendung als immunogene und vakzine.
ATA166890A (de) Rekombinantes dna-molekül für allergene des erlenpollens, damit hergestellte proteine bzw. polypeptide, sowie deren anwendung
ATE84315T1 (de) Rekombinante dna zur reprimierbaren und induzierbaren expression von fremdgenen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition