DE69530792D1 - Pharmazeutische zusammensetzung enthaltend proliposomen pulver zur inhalation - Google Patents

Pharmazeutische zusammensetzung enthaltend proliposomen pulver zur inhalation

Info

Publication number
DE69530792D1
DE69530792D1 DE69530792T DE69530792T DE69530792D1 DE 69530792 D1 DE69530792 D1 DE 69530792D1 DE 69530792 T DE69530792 T DE 69530792T DE 69530792 T DE69530792 T DE 69530792T DE 69530792 D1 DE69530792 D1 DE 69530792D1
Authority
DE
Germany
Prior art keywords
inhalation
pharmaceutical composition
composition containing
proliposome powder
proliposome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69530792T
Other languages
English (en)
Other versions
DE69530792T2 (de
Inventor
Katarina Bystroem
Per-Gunnar Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9404466A external-priority patent/SE9404466D0/xx
Priority claimed from SE9502369A external-priority patent/SE9502369D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE69530792D1 publication Critical patent/DE69530792D1/de
Application granted granted Critical
Publication of DE69530792T2 publication Critical patent/DE69530792T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69530792T 1994-12-22 1995-12-20 Pharmazeutische zusammensetzung enthaltend proliposomen pulver zur inhalation Expired - Lifetime DE69530792T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9404466 1994-12-22
SE9404466A SE9404466D0 (sv) 1994-12-22 1994-12-22 Process for the preparation of powders for inhalation
SE9502369 1995-06-30
SE9502369A SE9502369D0 (sv) 1995-06-30 1995-06-30 Process for the preparation of compositions for inhalation
PCT/SE1995/001560 WO1996019199A1 (en) 1994-12-22 1995-12-20 Proliposome powders for inhalation

Publications (2)

Publication Number Publication Date
DE69530792D1 true DE69530792D1 (de) 2003-06-18
DE69530792T2 DE69530792T2 (de) 2004-04-15

Family

ID=26662194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69530792T Expired - Lifetime DE69530792T2 (de) 1994-12-22 1995-12-20 Pharmazeutische zusammensetzung enthaltend proliposomen pulver zur inhalation

Country Status (32)

Country Link
US (1) US6045828A (de)
EP (1) EP0800383B1 (de)
JP (1) JPH10510830A (de)
KR (1) KR100432461B1 (de)
CN (1) CN1087932C (de)
AR (1) AR002009A1 (de)
AT (1) ATE240095T1 (de)
AU (1) AU693632B2 (de)
BR (1) BR9510512A (de)
CA (1) CA2208517A1 (de)
CZ (1) CZ286469B6 (de)
DE (1) DE69530792T2 (de)
DK (1) DK0800383T3 (de)
EE (1) EE03592B1 (de)
EG (1) EG23683A (de)
ES (1) ES2194931T3 (de)
FI (1) FI972653A (de)
HU (1) HUT77628A (de)
IL (1) IL116454A (de)
IS (1) IS1978B (de)
MY (1) MY114114A (de)
NO (1) NO320434B1 (de)
NZ (1) NZ298180A (de)
PL (1) PL184393B1 (de)
PT (1) PT800383E (de)
RU (1) RU2162689C2 (de)
SA (1) SA95160463B1 (de)
SK (1) SK284918B6 (de)
TR (1) TR199501633A1 (de)
TW (1) TW508248B (de)
UA (1) UA43886C2 (de)
WO (1) WO1996019199A1 (de)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SA95160463B1 (ar) * 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
TW497974B (en) * 1996-07-03 2002-08-11 Res Dev Foundation High dose liposomal aerosol formulations
EP0927025A4 (de) * 1996-09-18 2001-07-25 Dragoco Inc Trockene pulverzusammensetzung mit in liposomen verkapseltem wirkstoff
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
PL337722A1 (en) * 1997-06-27 2000-08-28 Astra Ab Novel combination antiasthmatic drugs
WO1999000111A1 (en) * 1997-06-27 1999-01-07 Astra Aktiebolag (Publ) Proliposome powders for inhalation stabilised by tocopherol
US7052678B2 (en) * 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6090407A (en) 1997-09-23 2000-07-18 Research Development Foundation Small particle liposome aerosols for delivery of anti-cancer drugs
US7348025B2 (en) 1997-09-23 2008-03-25 Research Development Foundation Small particle liposome aerosols for delivery of anticancer drugs
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
SE9704833D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New formulation
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
NZ511568A (en) * 1998-11-12 2003-08-29 Frank G An inhalation system using lipids for the delivery of bioactive compounds
EP1839648A3 (de) * 1998-11-12 2007-11-21 Transave, Inc. Inhalationssystem
WO2000030654A1 (en) * 1998-11-26 2000-06-02 Britannia Pharmaceuticals Limited Anti-asthmatic combinations comprising surface active phospholipids
GB9912639D0 (en) 1999-05-28 1999-07-28 Britannia Pharmaceuticals Ltd Improvements in and relating to treatment of respiratory conditions
EP1158958B1 (de) * 1999-03-05 2007-06-06 CHIESI FARMACEUTICI S.p.A. Verbesserte pulverformulierungen zur inhalation
EP1043016B1 (de) * 1999-03-30 2014-08-20 Sodic Sa Pflanzenextrakt auf Glycerid-, Phospholipid- und Phytosphingolipidbasis, Verfahren für die Gewinnung dieses Extrakts und ihn enthaltende kosmetische Zusammensetzungen
CA2367131C (en) 1999-04-05 2007-07-03 Solomon S. Steiner Methods for fine powder formation
MXPA01012169A (es) 1999-05-27 2002-06-21 Euro Celtique Sa Preparaciones para la aplicacion de agentes anti-infecciosos y/o anti-lamatorios para partes externas o internas del cuerpo humano o animal en la remodelacion funcional y cosmetica y tratamientos para reparacion de tejidos.
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
WO2001013891A2 (en) * 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
GB9928311D0 (en) * 1999-11-30 2000-01-26 Novartis Ag Organic compounds
DE10012151A1 (de) * 2000-03-13 2001-09-27 Gsf Forschungszentrum Umwelt Mittel zur Behandlung von Erkrankungen des Tracheo-Brochialtraktes, insbesondere der COPD
GB0008660D0 (en) * 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
DK2283817T3 (en) 2000-11-30 2016-09-05 Vectura Ltd Process for preparing particles for use in a pharmaceutical composition
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
WO2003043585A2 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
EP1458360B1 (de) 2001-12-19 2011-05-11 Novartis AG Pulmonale verabreichung von aminoglykosiden
AU2003201569B2 (en) * 2002-01-21 2008-09-11 Vasogen Ireland Limited Pharmaceutically acceptable phosphate-glycerol carrying bodies
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
CN1747738B (zh) * 2002-10-29 2010-11-24 川塞夫有限公司 缓释抗感染剂
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
CN1208052C (zh) 2003-03-20 2005-06-29 上海家化联合股份有限公司 一种辅酶q10前体脂质体及其制备方法
JP2006522634A (ja) 2003-04-14 2006-10-05 ベクトゥラ・リミテッド 投与効率を向上させるデバイス及び製薬組成
US20060147389A1 (en) * 2004-04-14 2006-07-06 Vectura Ltd. Devices and pharmaceutical compositions for enhancing dosing efficiency
US20040204439A1 (en) * 2003-04-14 2004-10-14 Staniforth John Nicholas Composition, device, and method for treating sexual dysfunction via inhalation
CN100427064C (zh) * 2003-04-16 2008-10-22 沈阳药科大学 一种制备脂质体的新方法
SI1699434T1 (sl) * 2003-09-02 2011-06-30 Norton Healthcare Ltd Postopek za pripravo zdravila
US20050214224A1 (en) * 2003-11-04 2005-09-29 Nektar Therapeutics Lipid formulations for spontaneous drug encapsulation
DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
ES2540886T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
KR101557502B1 (ko) 2005-09-14 2015-10-06 맨카인드 코포레이션 결정질 미립자 표면에 대한 활성제의 친화력의 증가를기반으로 하는 약물 제제의 방법
US8226975B2 (en) 2005-12-08 2012-07-24 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
CN1895223B (zh) * 2006-04-05 2012-06-27 沈阳药科大学 一种新的脂质体制备方法
US9814672B2 (en) * 2007-03-09 2017-11-14 Susan T. Laing Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi
AU2008227852B2 (en) * 2007-03-19 2011-02-24 Fresenius Kabi Oncology Ltd. Proliposomal and liposomal compositions
WO2008137717A1 (en) * 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US20090047336A1 (en) * 2007-08-17 2009-02-19 Hong Kong Baptist University novel formulation of dehydrated lipid vesicles for controlled release of active pharmaceutical ingredient via inhalation
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
PL2293833T3 (pl) * 2008-06-13 2016-08-31 Mannkind Corp Inhalator proszkowy i układ do dostarczania leku
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP4403231A2 (de) 2009-02-26 2024-07-24 Glaxo Group Limited Pharmazeutische formulierungen enthaltend 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
EP2405963B1 (de) 2009-03-11 2013-11-06 MannKind Corporation Gerät, system und verfahren zur messung von widerstand in einem inhaliergerät
KR20180079458A (ko) 2009-06-12 2018-07-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
CA2801936C (en) 2010-06-21 2021-06-01 Mannkind Corporation Dry powder drug delivery system and methods
EP2694402B1 (de) 2011-04-01 2017-03-22 MannKind Corporation Blisterverpackung für pharmakartuschen
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2776053A1 (de) 2011-10-24 2014-09-17 MannKind Corporation Verfahren und zusammensetzungen zur schmerzbehandlung
EP4005576B1 (de) 2012-05-21 2023-12-13 Insmed Incorporated Systeme zur behandlung von lungenentzündungen
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014028796A2 (en) 2012-08-17 2014-02-20 Smartek International Llc Preparation of desiccated liposomes for use in compressible delivery systems
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
AU2013352259B2 (en) 2012-11-29 2018-06-14 Insmed Incorporated Stabilized vancomycin formulations
KR102499439B1 (ko) 2013-03-15 2023-02-13 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
US9603799B2 (en) * 2013-03-15 2017-03-28 Htd Biosystems Inc. Liposomal vaccine adjuvants and methods of making and using same
MX2020009878A (es) 2013-07-18 2022-07-27 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos.
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US9895385B2 (en) 2014-05-15 2018-02-20 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ES2871537T3 (es) * 2016-05-09 2021-10-29 Astrazeneca Ab Nanopartículas lipídicas que comprenden agentes antiinflamatorios lipófilos y métodos de uso de las mismas
JP7460534B2 (ja) 2018-03-30 2024-04-02 インスメッド インコーポレイテッド リポソーム医薬品の連続製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US514674A (en) * 1894-02-13 Ejector for breakdown guns
DE2966795D1 (en) * 1978-10-12 1984-04-19 Bowater Scott Ltd Holder and dispenser for stacked rolls
GB2135647A (en) * 1983-02-15 1984-09-05 Squibb & Sons Inc Method of preparing liposomes and products produced thereby
US4744989A (en) * 1984-02-08 1988-05-17 E. R. Squibb & Sons, Inc. Method of preparing liposomes and products produced thereby
EP0158441B2 (de) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposombildende Zusammensetzung
SE8601457D0 (sv) * 1986-04-01 1986-04-01 Draco Ab Compositions of liposomes and b?712-receptor active substances for inhalation
SE8603812D0 (sv) * 1986-09-12 1986-09-12 Draco Ab Administration of liposomes to mammals
US5096629A (en) * 1988-08-29 1992-03-17 501 Nippon Fine Chemical Co., Ltd. Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes
CA2087902C (en) * 1992-02-05 2006-10-17 Narendra Raghunathji Desai Liposome compositions of porphyrin photosensitizers
AU7384894A (en) * 1993-08-06 1995-02-28 Opperbas Holding B.V. A method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers
US5635206A (en) * 1994-01-20 1997-06-03 Hoffmann-La Roche Inc. Process for liposomes or proliposomes
SA95160463B1 (ar) * 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق

Also Published As

Publication number Publication date
TW508248B (en) 2002-11-01
NO972847L (no) 1997-06-19
KR100432461B1 (ko) 2004-07-16
HUT77628A (hu) 1998-06-29
SA95160463B1 (ar) 2005-10-04
EP0800383A1 (de) 1997-10-15
FI972653A0 (fi) 1997-06-19
NZ298180A (en) 1999-01-28
CZ194897A3 (en) 1997-10-15
BR9510512A (pt) 1998-07-07
IS4500A (is) 1997-06-06
MY114114A (en) 2002-08-30
SK81497A3 (en) 1997-11-05
JPH10510830A (ja) 1998-10-20
ATE240095T1 (de) 2003-05-15
RU2162689C2 (ru) 2001-02-10
SK284918B6 (sk) 2006-02-02
EE03592B1 (et) 2002-02-15
AR002009A1 (es) 1998-01-07
EP0800383B1 (de) 2003-05-14
TR199501633A1 (tr) 1997-03-21
AU693632B2 (en) 1998-07-02
IL116454A (en) 2002-03-10
DK0800383T3 (da) 2003-07-07
ES2194931T3 (es) 2003-12-01
AU4360596A (en) 1996-07-10
NO972847D0 (no) 1997-06-19
EG23683A (en) 2007-05-09
CN1171047A (zh) 1998-01-21
PT800383E (pt) 2003-07-31
UA43886C2 (uk) 2002-01-15
PL184393B1 (pl) 2002-10-31
DE69530792T2 (de) 2004-04-15
MX9704406A (es) 1997-10-31
FI972653A (fi) 1997-08-20
PL320825A1 (en) 1997-11-10
NO320434B1 (no) 2005-12-05
IL116454A0 (en) 1996-03-31
EE9700134A (et) 1997-12-15
CZ286469B6 (en) 2000-04-12
CA2208517A1 (en) 1996-06-27
IS1978B (is) 2005-01-14
US6045828A (en) 2000-04-04
WO1996019199A1 (en) 1996-06-27
CN1087932C (zh) 2002-07-24

Similar Documents

Publication Publication Date Title
ATE240095T1 (de) Pharmazeutische zusammensetzung enthaltend proliposomen pulver zur inhalation
EP0768094A3 (de) Inhalator für Arzneimittel in Pulverform
ZA9810490B (en) 2-Aryl-8-oxodihydropurine derivative process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor
HUP9802999A3 (en) Pharmaceutical composition containing n-propargyl-1-aminoindan
IL120246A0 (en) Powdered medication inhaler
HUP0104255A3 (en) An pharmaceutical composition suitable for inhalation
IL99521A0 (en) Nasal pharmaceutical composition
HUP9701554D0 (en) Pharmaceutical composition containing plazma proteins
NO953388D0 (no) Medikamentbærer for törr-pulver inhalator
IL116211A0 (en) Peptide compounds pharmaceutical compositions containing the same and processes for the preparation thereof
IL118369A0 (en) Piperazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
SG52435A1 (en) Pharmaceutical composition containing lipophilic drugs
HUP9903407A3 (en) Oral pharmaceutical preparation containing ibandronat
IL122618A0 (en) Substituted imidazolylacetonitrile compounds their preparation and pharmaceutical compositions containing them
ZA962916B (en) New arylglycineamide derivatives processes for the manufacture thereof and pharmaceutical compositions containing these compounds
AP9701160A0 (en) Compounds and pharmaceutical compositions containing them
IL117620A0 (en) Heterocyclic compounds processes for the preparation thereof and pharmaceutical compositions containing the same
IL125820A0 (en) Therapeutic agent for diabetes and a pharmaceutical composition containing the same
EP0448091A3 (en) Pharmaceutical composition containing slightly water-soluble drug
IL116771A (en) 9-Substituted 2-(2-n-alkoxyphenyl) purin-6-one compounds their preparation and pharmaceutical compositions containing them
HK1035719A1 (en) Azabicyclic compounds, pharmaceutical composition containing them and their medicinal use
IL133928A0 (en) Pharmaceutical composition containing peptichemio
IL117397A (en) Substituted naphthyl compounds and pharmaceutical compositions comprising them
IL115272A0 (en) Asp-pallidipin pharmaceutical compositions containing the same and processes for the preparation thereof
IL118007A0 (en) Isoxazoline compounds pharmaceutical compositions containing them and their use

Legal Events

Date Code Title Description
8364 No opposition during term of opposition