DE69528068T2 - Conagenine zur prävention und behandlung von diarrhöe - Google Patents

Conagenine zur prävention und behandlung von diarrhöe

Info

Publication number
DE69528068T2
DE69528068T2 DE69528068T DE69528068T DE69528068T2 DE 69528068 T2 DE69528068 T2 DE 69528068T2 DE 69528068 T DE69528068 T DE 69528068T DE 69528068 T DE69528068 T DE 69528068T DE 69528068 T2 DE69528068 T2 DE 69528068T2
Authority
DE
Germany
Prior art keywords
preventing
conagenine
diarrhoe
treating
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69528068T
Other languages
English (en)
Other versions
DE69528068D1 (de
Inventor
Masaaki Ishizuka
Kenji Maeda
Tomio Takeuchi
Toshiyuki Toko
Tadayoshi Shiraishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Taiho Pharmaceutical Co Ltd
Original Assignee
Microbial Chemistry Research Foundation
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation, Taiho Pharmaceutical Co Ltd filed Critical Microbial Chemistry Research Foundation
Application granted granted Critical
Publication of DE69528068D1 publication Critical patent/DE69528068D1/de
Publication of DE69528068T2 publication Critical patent/DE69528068T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE69528068T 1994-10-14 1995-10-13 Conagenine zur prävention und behandlung von diarrhöe Expired - Fee Related DE69528068T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24946694 1994-10-14
JP20820195A JP4078397B2 (ja) 1994-10-14 1995-08-15 下痢の予防及び治療剤
PCT/JP1995/002107 WO1996011681A1 (fr) 1994-10-14 1995-10-13 Antidiarrheique therapeutique et preventif

Publications (2)

Publication Number Publication Date
DE69528068D1 DE69528068D1 (de) 2002-10-10
DE69528068T2 true DE69528068T2 (de) 2003-10-02

Family

ID=26516699

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69528068T Expired - Fee Related DE69528068T2 (de) 1994-10-14 1995-10-13 Conagenine zur prävention und behandlung von diarrhöe

Country Status (9)

Country Link
US (1) US5952380A (de)
EP (1) EP0783884B1 (de)
JP (1) JP4078397B2 (de)
KR (1) KR100369890B1 (de)
AT (1) ATE223212T1 (de)
AU (1) AU691674B2 (de)
CA (1) CA2202389A1 (de)
DE (1) DE69528068T2 (de)
WO (1) WO1996011681A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4078397B2 (ja) * 1994-10-14 2008-04-23 財団法人微生物化学研究会 下痢の予防及び治療剤
KR100356899B1 (ko) * 1997-04-09 2002-10-31 다이호야쿠힌고교 가부시키가이샤 궤양성 대장염 및/또는 크론병 예방 및 치료제
JPWO2007011066A1 (ja) * 2005-07-22 2009-02-05 株式会社カネカ 繊維芽細胞賦活剤、コラーゲン産生促進剤、コラーゲン収縮促進剤、ヒアルロン酸産生促進剤、ａｔｐ産生促進剤、メラニン生成抑制剤、皮膚外用剤
CN110714050A (zh) * 2018-07-13 2020-01-21 永州职业技术学院 一种基于多种微生物的急性毒性试验方法及其试剂盒

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2837870B2 (ja) * 1989-05-23 1998-12-16 財団法人微生物化学研究会 新規な制癌抗生物質コナゲニン及びその製造法
JPH04112865A (ja) * 1990-09-03 1992-04-14 Dainippon Pharmaceut Co Ltd 置換アミド誘導体
JPH0798752B2 (ja) * 1991-08-09 1995-10-25 株式会社ツムラ β−グルクロニダーゼ阻害剤
JPH0665072A (ja) * 1992-08-17 1994-03-08 Microbial Chem Res Found 化学療法剤及び又は放射線による副作用の軽減剤
JP4078397B2 (ja) * 1994-10-14 2008-04-23 財団法人微生物化学研究会 下痢の予防及び治療剤

Also Published As

Publication number Publication date
EP0783884A4 (de) 1999-06-23
WO1996011681A1 (fr) 1996-04-25
CA2202389A1 (en) 1996-04-25
DE69528068D1 (de) 2002-10-10
AU691674B2 (en) 1998-05-21
JP4078397B2 (ja) 2008-04-23
KR970705987A (ko) 1997-11-03
JPH08165236A (ja) 1996-06-25
US5952380A (en) 1999-09-14
ATE223212T1 (de) 2002-09-15
EP0783884A1 (de) 1997-07-16
KR100369890B1 (ko) 2003-05-12
EP0783884B1 (de) 2002-09-04
AU3673795A (en) 1996-05-06

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8339 Ceased/non-payment of the annual fee