DE69515770T2 - Verfahren zur Produktion von Thiophospholipiden des Aether-Typs - Google Patents

Verfahren zur Produktion von Thiophospholipiden des Aether-Typs

Info

Publication number
DE69515770T2
DE69515770T2 DE69515770T DE69515770T DE69515770T2 DE 69515770 T2 DE69515770 T2 DE 69515770T2 DE 69515770 T DE69515770 T DE 69515770T DE 69515770 T DE69515770 T DE 69515770T DE 69515770 T2 DE69515770 T2 DE 69515770T2
Authority
DE
Germany
Prior art keywords
ether
type
chem
thiophospholipids
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69515770T
Other languages
English (en)
Other versions
DE69515770D1 (de
Inventor
Mitsuaki Ohtani
Masahiro Fuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anthera Pharmaceuticals Inc
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE69515770D1 publication Critical patent/DE69515770D1/de
Application granted granted Critical
Publication of DE69515770T2 publication Critical patent/DE69515770T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69515770T 1994-09-20 1995-09-15 Verfahren zur Produktion von Thiophospholipiden des Aether-Typs Expired - Fee Related DE69515770T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22467994A JP3839857B2 (ja) 1994-09-20 1994-09-20 エーテル型チオリン脂質化合物の製造方法

Publications (2)

Publication Number Publication Date
DE69515770D1 DE69515770D1 (de) 2000-04-27
DE69515770T2 true DE69515770T2 (de) 2000-07-27

Family

ID=16817531

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69515770T Expired - Fee Related DE69515770T2 (de) 1994-09-20 1995-09-15 Verfahren zur Produktion von Thiophospholipiden des Aether-Typs

Country Status (12)

Country Link
US (3) US5663405A (de)
EP (1) EP0703237B1 (de)
JP (1) JP3839857B2 (de)
KR (1) KR100367438B1 (de)
AT (1) ATE190979T1 (de)
CA (1) CA2158381A1 (de)
DE (1) DE69515770T2 (de)
DK (1) DK0703237T3 (de)
ES (1) ES2145223T3 (de)
GR (1) GR3033172T3 (de)
PT (1) PT703237E (de)
TW (1) TW294671B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2290947A1 (en) * 1996-05-28 1997-12-04 Fred I. Chasalow Phosphocholinate cardenolides
DE102009052034A1 (de) * 2009-11-05 2011-05-12 Merck Patent Gmbh Synthese von Phosphorestern
KR102063513B1 (ko) 2012-05-02 2020-01-08 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 방향족 분산제 조성물
EP3039056B1 (de) 2013-08-29 2020-03-04 Lubrizol Advanced Materials, Inc. Nichtkondensierte aromatische dispergiermittelzusammensetzung
CN106967113A (zh) * 2017-04-05 2017-07-21 西北农林科技大学 血小板活化因子衍生物及其合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221696A (en) * 1989-03-29 1993-06-22 Alcon Laboratories, Inc. Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs
JP2899061B2 (ja) * 1990-05-18 1999-06-02 協和メデックス株式会社 カルシウムの定量法
JP3204681B2 (ja) 1991-05-24 2001-09-04 株式会社シノテスト 新規なエーテル型チオリン脂質化合物およびその製造法
US5304325A (en) * 1991-11-13 1994-04-19 Hemagen/Pfc Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
US5464754A (en) * 1993-08-17 1995-11-07 The Regents Of The University Of California Assay and substrate for arachidonoyl-specific phospholipase A2
DE4418690A1 (de) * 1994-05-28 1996-01-11 Boehringer Mannheim Gmbh Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel

Also Published As

Publication number Publication date
JP3839857B2 (ja) 2006-11-01
PT703237E (pt) 2000-07-31
EP0703237B1 (de) 2000-03-22
KR100367438B1 (ko) 2003-03-15
ATE190979T1 (de) 2000-04-15
DE69515770D1 (de) 2000-04-27
GR3033172T3 (en) 2000-08-31
KR960010665A (ko) 1996-04-20
JPH0892265A (ja) 1996-04-09
EP0703237A1 (de) 1996-03-27
DK0703237T3 (da) 2000-07-10
US5760270A (en) 1998-06-02
ES2145223T3 (es) 2000-07-01
CA2158381A1 (en) 1996-03-21
US5981778A (en) 1999-11-09
TW294671B (de) 1997-01-01
US5663405A (en) 1997-09-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ANTHERA PHARMACEUTICALS INC., SAN MATEO, CALIF, US

8339 Ceased/non-payment of the annual fee