DE69517201T2 - Verfahren zur herstellung von 2-(2-hydroxymethylphenyl)acetamid-derivaten und zwischenprodukte zur herstellung - Google Patents

Verfahren zur herstellung von 2-(2-hydroxymethylphenyl)acetamid-derivaten und zwischenprodukte zur herstellung

Info

Publication number
DE69517201T2
DE69517201T2 DE69517201T DE69517201T DE69517201T2 DE 69517201 T2 DE69517201 T2 DE 69517201T2 DE 69517201 T DE69517201 T DE 69517201T DE 69517201 T DE69517201 T DE 69517201T DE 69517201 T2 DE69517201 T2 DE 69517201T2
Authority
DE
Germany
Prior art keywords
production
hydroxymethylphenyl
intermediate products
acetamide derivatives
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69517201T
Other languages
English (en)
Other versions
DE69517201D1 (de
Inventor
Akira Takase
Hiroyuki Kai
Takami Murashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE69517201D1 publication Critical patent/DE69517201D1/de
Application granted granted Critical
Publication of DE69517201T2 publication Critical patent/DE69517201T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/56Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having carbon atoms of carboxamide groups bound to carbon atoms of carboxyl groups, e.g. oxamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/12Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/34Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14Unsaturated ethers
    • C07C43/17Unsaturated ethers containing halogen
    • C07C43/174Unsaturated ethers containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69517201T 1994-12-26 1995-12-21 Verfahren zur herstellung von 2-(2-hydroxymethylphenyl)acetamid-derivaten und zwischenprodukte zur herstellung Expired - Fee Related DE69517201T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32213094 1994-12-26
PCT/JP1995/002621 WO1996020164A1 (fr) 1994-12-26 1995-12-21 Procede de production de derive de 2-(2-hydroxymethylphenyl)acetamide et intermediaire utilise pour sa production

Publications (2)

Publication Number Publication Date
DE69517201D1 DE69517201D1 (de) 2000-06-29
DE69517201T2 true DE69517201T2 (de) 2000-09-28

Family

ID=18140271

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69517201T Expired - Fee Related DE69517201T2 (de) 1994-12-26 1995-12-21 Verfahren zur herstellung von 2-(2-hydroxymethylphenyl)acetamid-derivaten und zwischenprodukte zur herstellung

Country Status (13)

Country Link
US (2) US5856573A (de)
EP (1) EP0801054B1 (de)
KR (1) KR980700956A (de)
CN (1) CN1082046C (de)
AT (1) ATE193281T1 (de)
AU (1) AU4314596A (de)
DE (1) DE69517201T2 (de)
DK (1) DK0801054T3 (de)
ES (1) ES2148587T3 (de)
GR (1) GR3033503T3 (de)
PT (1) PT801054E (de)
TW (1) TW363957B (de)
WO (1) WO1996020164A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9521343D0 (en) * 1995-10-18 1995-12-20 Zeneca Ltd Fungicides
WO1999025713A1 (en) 1997-11-14 1999-05-27 Dow Agrosciences Llc 2-methoxyimino-2-phenyl acetamides containing a ketal- or dialkoxy substituted pyridine moiety, their preparation and their use as fungicides
AU6251799A (en) 1998-09-16 2000-04-03 Dow Agrosciences Llc 2-methoxyimino -2-(pyridinyloxymethyl) phenyl acetamides useful as fungicides
AU6049199A (en) 1998-09-16 2000-04-03 Dow Agrosciences Llc 2-methoxyimino-2-(pyridinyloxymethyl)phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring
WO2000015637A1 (en) * 1998-09-16 2000-03-23 Dow Agrosciences Llc 2-methoxyimino -2-(pyridinyloxymethyl) phenyl acetamides with 5 membered heterocyclic rings on the pyridine ring as fungicides
JP2003516968A (ja) 1999-12-15 2003-05-20 ダウ・アグロサイエンス・エル・エル・シー 殺菌・カビ活性を有するピリジン誘導体及びその製造方法及び使用
CN105503642B (zh) * 2015-12-17 2017-09-15 湖南科技大学 N‑取代‑2‑(2‑羟基苄基)氨基乙酰胺类化合物及其制备和用途
GB201910037D0 (en) 2019-07-12 2019-08-28 Syngenta Crop Protection Ag Microbiocidal compounds
GB202006386D0 (en) 2020-04-30 2020-06-17 Syngenta Crop Protection Ag Microbiocidal Compounds
GB202006480D0 (en) 2020-05-01 2020-06-17 Syngenta Crop Protection Ag Microbiocidal compounds
GB202014840D0 (en) 2020-09-21 2020-11-04 Syngenta Crop Protection Ag Microbiocidal compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5534121B2 (de) * 1972-06-19 1980-09-04
US4912276A (en) * 1988-10-25 1990-03-27 Eastman Kodak Company Preparation of biaryl compounds
DE4030038A1 (de) * 1990-09-22 1992-03-26 Basf Ag Ortho-substituierte phenylessigsaeureamide
JP3121061B2 (ja) * 1991-10-04 2000-12-25 塩野義製薬株式会社 アルコキシイミノアセトアミド類製造用中間体の製造法およびそれに用いる中間体
US5258551A (en) * 1991-12-18 1993-11-02 Shionogi & Co., Ltd. Process for producing α-ketoamide derivative
US5506358A (en) * 1993-03-16 1996-04-09 Shionogi & Co., Ltd. Process for producing alkoxyiminoacetamide compounds
JP3573480B2 (ja) * 1994-02-21 2004-10-06 大正製薬株式会社 プロスタグランジン誘導体およびその使用

Also Published As

Publication number Publication date
CN1175244A (zh) 1998-03-04
TW363957B (en) 1999-07-11
US5856573A (en) 1999-01-05
US6147231A (en) 2000-11-14
DE69517201D1 (de) 2000-06-29
AU4314596A (en) 1996-07-19
KR980700956A (ko) 1998-04-30
PT801054E (pt) 2000-08-31
ES2148587T3 (es) 2000-10-16
CN1082046C (zh) 2002-04-03
DK0801054T3 (da) 2000-08-07
EP0801054B1 (de) 2000-05-24
EP0801054A4 (de) 1998-12-23
WO1996020164A1 (fr) 1996-07-04
ATE193281T1 (de) 2000-06-15
EP0801054A1 (de) 1997-10-15
GR3033503T3 (en) 2000-09-29

Similar Documents

Publication Publication Date Title
ATE282020T1 (de) Verfahren zur herstellung von 2-aminomalonsäure- derivaten
DE69415319D1 (de) Verfahren zur herstellung von piperidinderivaten
DE69517201T2 (de) Verfahren zur herstellung von 2-(2-hydroxymethylphenyl)acetamid-derivaten und zwischenprodukte zur herstellung
DE69719781D1 (de) Zwischenprodukte zur Herstellung von Duocarmycin SA und dessen Derivaten sowie ein Verfahren zur Herstellung der Zwischenprodukte
ATE204870T1 (de) Verfahren zur herstellung von paroxetine
DE69814635D1 (de) Verfahren zur herstellung von 2-hydroxybenzamidderivaten
ATE115551T1 (de) Verfahren zur herstellung von methoxyiminoacetamidverbindungen und zwischenverbindungen.
ATE191461T1 (de) Verfahren zur herstellung von alkoxyimino acetamid-derivaten
DE60010243D1 (de) Verfahren und vorrichtung zur herstellung von monofonktionellen haloameisensäurearylestern
ATE234820T1 (de) Aminoalkyloxime, verfahren zur dessen herstellung,ihre verwendung als medikamente und zwischenprodukte
DE69839732D1 (de) Verfahren zur herstellung von 3,4-dihydroxy-3cyclobuten-1,2-dion
ATE226570T1 (de) Verfahren zur herstellung von halogenacetamidderivaten
DE69518252T2 (de) Verfahren zur herstellung von 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalin-derivaten
DE69515770D1 (de) Verfahren zur Produktion von Thiophospholipiden des Aether-Typs
ATE423089T1 (de) Verfahren zur herstellung von butantriol- derivaten
ATE224393T1 (de) Verfahren zur herstellung von cephalosporinen und zwischenverbindungen in diesem verfahren
ATE189887T1 (de) Vitamin-d-derivat und verfahren zu seiner herstellung
HU913055D0 (en) An improved method for producing 4-methyl-sulfonyl-benzoic acid derivatives and their intermediate products
DE69530229D1 (de) Verfahren zur herstellung von 1,5-pentandiol-derivaten
ATE260922T1 (de) Verfahren und zwischenprodukte zur herstellung von 5,7-dihydro-3-(2 1-benzylpiperidin-4-yl
ATE228993T1 (de) Verfahren zur herstellung von 1,1,1-trifluoro-2- aminoalkane
ATE240298T1 (de) Verfahren zur herstellung von chlorpyridinen
DE3881458D1 (de) Verfahren zur herstellung von makrolid-derivaten.
DE69608030T2 (de) Verfahren zur Herstellung von 2-Naphthamid-Derivate, und Zwischenprodukte zur Herstellung von 2-Naphthamid-Derivate
ATE247618T1 (de) Verfahren zur herstellung von 1,4-diaryl-2-fluor- 1,3-butadien- und 1,4-diaryl-2-fluor-2- butenverbindungen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee