DE69515770D1 - Verfahren zur Produktion von Thiophospholipiden des Aether-Typs - Google Patents
Verfahren zur Produktion von Thiophospholipiden des Aether-TypsInfo
- Publication number
- DE69515770D1 DE69515770D1 DE69515770T DE69515770T DE69515770D1 DE 69515770 D1 DE69515770 D1 DE 69515770D1 DE 69515770 T DE69515770 T DE 69515770T DE 69515770 T DE69515770 T DE 69515770T DE 69515770 D1 DE69515770 D1 DE 69515770D1
- Authority
- DE
- Germany
- Prior art keywords
- ether
- type
- chem
- thiophospholipids
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102100037611 Lysophospholipase Human genes 0.000 abstract 1
- 108020002496 Lysophospholipase Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000003358 phospholipase A2 inhibitor Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/02—Monothiocarboxylic acids
- C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22467994A JP3839857B2 (ja) | 1994-09-20 | 1994-09-20 | エーテル型チオリン脂質化合物の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69515770D1 true DE69515770D1 (de) | 2000-04-27 |
DE69515770T2 DE69515770T2 (de) | 2000-07-27 |
Family
ID=16817531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69515770T Expired - Fee Related DE69515770T2 (de) | 1994-09-20 | 1995-09-15 | Verfahren zur Produktion von Thiophospholipiden des Aether-Typs |
Country Status (12)
Country | Link |
---|---|
US (3) | US5663405A (de) |
EP (1) | EP0703237B1 (de) |
JP (1) | JP3839857B2 (de) |
KR (1) | KR100367438B1 (de) |
AT (1) | ATE190979T1 (de) |
CA (1) | CA2158381A1 (de) |
DE (1) | DE69515770T2 (de) |
DK (1) | DK0703237T3 (de) |
ES (1) | ES2145223T3 (de) |
GR (1) | GR3033172T3 (de) |
PT (1) | PT703237E (de) |
TW (1) | TW294671B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2290947A1 (en) * | 1996-05-28 | 1997-12-04 | Fred I. Chasalow | Phosphocholinate cardenolides |
DE102009052034A1 (de) | 2009-11-05 | 2011-05-12 | Merck Patent Gmbh | Synthese von Phosphorestern |
CN104411739B (zh) | 2012-05-02 | 2017-03-08 | 路博润高级材料公司 | 芳族分散剂组合物 |
CN105683249B (zh) | 2013-08-29 | 2018-07-10 | 路博润先进材料公司 | 非稠合芳族分散剂组合物 |
CN106967113A (zh) * | 2017-04-05 | 2017-07-21 | 西北农林科技大学 | 血小板活化因子衍生物及其合成方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5221696A (en) * | 1989-03-29 | 1993-06-22 | Alcon Laboratories, Inc. | Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs |
JP2899061B2 (ja) * | 1990-05-18 | 1999-06-02 | 協和メデックス株式会社 | カルシウムの定量法 |
JP3204681B2 (ja) | 1991-05-24 | 2001-09-04 | 株式会社シノテスト | 新規なエーテル型チオリン脂質化合物およびその製造法 |
US5304325A (en) * | 1991-11-13 | 1994-04-19 | Hemagen/Pfc | Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use |
US5464754A (en) * | 1993-08-17 | 1995-11-07 | The Regents Of The University Of California | Assay and substrate for arachidonoyl-specific phospholipase A2 |
DE4418690A1 (de) * | 1994-05-28 | 1996-01-11 | Boehringer Mannheim Gmbh | Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel |
-
1994
- 1994-09-20 JP JP22467994A patent/JP3839857B2/ja not_active Expired - Fee Related
-
1995
- 1995-09-15 DE DE69515770T patent/DE69515770T2/de not_active Expired - Fee Related
- 1995-09-15 PT PT95306514T patent/PT703237E/pt unknown
- 1995-09-15 DK DK95306514T patent/DK0703237T3/da active
- 1995-09-15 EP EP95306514A patent/EP0703237B1/de not_active Expired - Lifetime
- 1995-09-15 CA CA002158381A patent/CA2158381A1/en not_active Abandoned
- 1995-09-15 ES ES95306514T patent/ES2145223T3/es not_active Expired - Lifetime
- 1995-09-15 AT AT95306514T patent/ATE190979T1/de not_active IP Right Cessation
- 1995-09-16 TW TW084109747A patent/TW294671B/zh active
- 1995-09-19 US US08/530,763 patent/US5663405A/en not_active Expired - Fee Related
- 1995-09-19 KR KR1019950030574A patent/KR100367438B1/ko not_active IP Right Cessation
-
1997
- 1997-04-23 US US08/847,771 patent/US5760270A/en not_active Expired - Fee Related
-
1998
- 1998-03-23 US US09/045,924 patent/US5981778A/en not_active Expired - Lifetime
-
2000
- 2000-04-07 GR GR20000400865T patent/GR3033172T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT703237E (pt) | 2000-07-31 |
US5760270A (en) | 1998-06-02 |
EP0703237A1 (de) | 1996-03-27 |
JPH0892265A (ja) | 1996-04-09 |
JP3839857B2 (ja) | 2006-11-01 |
KR100367438B1 (ko) | 2003-03-15 |
GR3033172T3 (en) | 2000-08-31 |
CA2158381A1 (en) | 1996-03-21 |
DK0703237T3 (da) | 2000-07-10 |
KR960010665A (ko) | 1996-04-20 |
TW294671B (de) | 1997-01-01 |
US5981778A (en) | 1999-11-09 |
ES2145223T3 (es) | 2000-07-01 |
DE69515770T2 (de) | 2000-07-27 |
EP0703237B1 (de) | 2000-03-22 |
US5663405A (en) | 1997-09-02 |
ATE190979T1 (de) | 2000-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ANTHERA PHARMACEUTICALS INC., SAN MATEO, CALIF, US |
|
8339 | Ceased/non-payment of the annual fee |