DE69511422D1 - Durchflussvorrichtung und verfahren zur elektroporation - Google Patents

Durchflussvorrichtung und verfahren zur elektroporation

Info

Publication number
DE69511422D1
DE69511422D1 DE69511422T DE69511422T DE69511422D1 DE 69511422 D1 DE69511422 D1 DE 69511422D1 DE 69511422 T DE69511422 T DE 69511422T DE 69511422 T DE69511422 T DE 69511422T DE 69511422 D1 DE69511422 D1 DE 69511422D1
Authority
DE
Germany
Prior art keywords
flow
blood
patient
cells
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69511422T
Other languages
English (en)
Other versions
DE69511422T2 (de
Inventor
Gunter Hofmann
Henry Kent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetronics Inc
Original Assignee
Genetronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetronics Inc filed Critical Genetronics Inc
Publication of DE69511422D1 publication Critical patent/DE69511422D1/de
Application granted granted Critical
Publication of DE69511422T2 publication Critical patent/DE69511422T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Electromagnetism (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Sustainable Development (AREA)
  • Cardiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Anesthesiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Apparatuses And Processes For Manufacturing Resistors (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • External Artificial Organs (AREA)
DE69511422T 1994-10-12 1995-10-12 Durchflussvorrichtung und verfahren zur elektroporation Expired - Fee Related DE69511422T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/320,966 US5545130A (en) 1992-04-08 1994-10-12 Flow through electroporation method
PCT/US1995/014622 WO1996012006A2 (en) 1994-10-12 1995-10-12 Flow through electroporation apparatus and method

Publications (2)

Publication Number Publication Date
DE69511422D1 true DE69511422D1 (de) 1999-09-16
DE69511422T2 DE69511422T2 (de) 2000-02-03

Family

ID=23248604

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69511422T Expired - Fee Related DE69511422T2 (de) 1994-10-12 1995-10-12 Durchflussvorrichtung und verfahren zur elektroporation

Country Status (8)

Country Link
US (2) US5545130A (de)
EP (1) EP0785987B1 (de)
JP (1) JP3740664B2 (de)
AT (1) ATE183231T1 (de)
AU (1) AU691705B2 (de)
CA (1) CA2196610C (de)
DE (1) DE69511422T2 (de)
WO (1) WO1996012006A2 (de)

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Also Published As

Publication number Publication date
AU4153696A (en) 1996-05-06
JP3740664B2 (ja) 2006-02-01
ATE183231T1 (de) 1999-08-15
CA2196610A1 (en) 1996-04-25
WO1996012006A3 (en) 1996-08-01
JPH10507364A (ja) 1998-07-21
AU691705B2 (en) 1998-05-21
WO1996012006A2 (en) 1996-04-25
EP0785987B1 (de) 1999-08-11
US5545130A (en) 1996-08-13
EP0785987A2 (de) 1997-07-30
CA2196610C (en) 2004-07-20
DE69511422T2 (de) 2000-02-03
US5676646A (en) 1997-10-14

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