DE69427515D1 - Neuartiger genvektor codierend fur den epidermis wachstumsfaktor und verfahren zu seiner herstellung - Google Patents

Neuartiger genvektor codierend fur den epidermis wachstumsfaktor und verfahren zu seiner herstellung

Info

Publication number
DE69427515D1
DE69427515D1 DE69427515T DE69427515T DE69427515D1 DE 69427515 D1 DE69427515 D1 DE 69427515D1 DE 69427515 T DE69427515 T DE 69427515T DE 69427515 T DE69427515 T DE 69427515T DE 69427515 D1 DE69427515 D1 DE 69427515D1
Authority
DE
Germany
Prior art keywords
genector
innovative
coding
production
growth factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69427515T
Other languages
English (en)
Other versions
DE69427515T2 (de
Inventor
Moon Lee
Kook Park
Seung Nho
Wook Koh
Hyuk Kwon
Young Chung
Su Jee
Hyo Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daewoong Pharmaceutical Co Ltd
Original Assignee
Daewoong Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019930006980A external-priority patent/KR970001508B1/ko
Priority claimed from KR1019930006979A external-priority patent/KR960006121B1/ko
Priority claimed from KR1019930006978A external-priority patent/KR960010951B1/ko
Application filed by Daewoong Pharmaceutical Co Ltd filed Critical Daewoong Pharmaceutical Co Ltd
Publication of DE69427515D1 publication Critical patent/DE69427515D1/de
Application granted granted Critical
Publication of DE69427515T2 publication Critical patent/DE69427515T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69427515T 1993-04-26 1994-04-25 Neuartiger genvektor codierend fur den epidermis wachstumsfaktor und verfahren zu seiner herstellung Expired - Lifetime DE69427515T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR1019930006980A KR970001508B1 (ko) 1993-04-26 1993-04-26 재조합 인간 상피세포 성장인자의 정제방법
KR1019930006979A KR960006121B1 (ko) 1993-04-26 1993-04-26 인간 상피세포 성장인자(hEGF) 발현벡터 및 그를 이용한 hEGF의 제조방법
KR1019930006978A KR960010951B1 (ko) 1993-04-26 1993-04-26 신규한 인간 상피세포 성장인자 유전자
PCT/KR1994/000036 WO1994025592A1 (en) 1993-04-26 1994-04-25 A novel gene coding human epidermal growth factor and process for preparing the same

Publications (2)

Publication Number Publication Date
DE69427515D1 true DE69427515D1 (de) 2001-07-26
DE69427515T2 DE69427515T2 (de) 2001-10-04

Family

ID=27348946

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427515T Expired - Lifetime DE69427515T2 (de) 1993-04-26 1994-04-25 Neuartiger genvektor codierend fur den epidermis wachstumsfaktor und verfahren zu seiner herstellung

Country Status (6)

Country Link
US (1) US5652120A (de)
EP (1) EP0652954B1 (de)
JP (1) JP2609515B2 (de)
AU (1) AU6582594A (de)
DE (1) DE69427515T2 (de)
WO (1) WO1994025592A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100447530B1 (ko) * 2001-08-14 2004-09-08 한국과학기술원 ＯｍｐＦ를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법
CA2427190A1 (en) * 2002-04-30 2003-10-30 Alberta Research Council Inc. Production of recombinant epidermal growth factor in plants
TW200927161A (en) * 2007-11-15 2009-07-01 Posh Cosmeceuticals Inc Composition containing granulocyte colony stimulating factor (GCSF) for hair growth
CN103484471B (zh) * 2013-09-30 2015-07-08 王悦 人表皮细胞生长因子核酸序列及大肠杆菌表达载体
KR102013788B1 (ko) * 2016-11-04 2019-08-23 한국과학기술연구원 인간상피세포 성장인자 또는 피부침투성 인간상피세포 성장인자 발현용 벡터 및 상기 벡터로 형질전환된 미세조류
KR102091170B1 (ko) * 2018-04-20 2020-03-19 티앤에이치바이오(주) 상피세포 성장인자의 생산 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53166B1 (en) * 1980-08-05 1988-08-03 Searle & Co Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression
DE3382547D1 (de) * 1983-01-12 1992-05-27 Chiron Corp Sekretorische expression in eukaryoten.
US5096825A (en) * 1983-01-12 1992-03-17 Chiron Corporation Gene for human epidermal growth factor and synthesis and expression thereof
JPS6028994A (ja) * 1983-07-08 1985-02-14 Wakunaga Seiyaku Kk 〔２１―ロイシン〕ヒトウロガストロン
JPS60130393A (ja) * 1983-12-19 1985-07-11 Sumitomo Chem Co Ltd ヒトウロガストロン遺伝子，対応する組換えプラズミド及び組換え体
JP2554459B2 (ja) * 1984-07-02 1996-11-13 アース製薬 株式会社 β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体
JPS61291598A (ja) * 1985-06-18 1986-12-22 Sagami Chem Res Center 魚類カルシトニン誘導体及びその製造方法
CA1263619A (en) * 1984-10-09 1989-12-05 Ryuji Marumoto Dna, production and use thereof
JPH0642833B2 (ja) * 1984-10-09 1994-06-08 武田薬品工業株式会社 ヒト表皮細胞増殖因子の遺伝子
JPH0644866B2 (ja) * 1985-08-13 1994-06-15 武田薬品工業株式会社 ヒト表皮細胞増殖因子生産用形質転換体
US4935350A (en) * 1985-11-18 1990-06-19 Amgen Materials and methods for controlling plasmid copy number and stability
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
JPH01247098A (ja) * 1988-03-30 1989-10-02 Hitachi Ltd ヒトの上皮細胞増殖因子の遺伝子工学的生産方法
DE68915841T2 (de) * 1988-03-30 1995-02-02 Hitachi Ltd Verfahren zur Herstellung von Epidermal-Wachstumsfaktor durch genetische Transformation.
JPH01257482A (ja) * 1988-04-08 1989-10-13 Hitachi Ltd ヒト表皮増殖因子生産のための合成遺伝子を有するｄｎａ及びそのプラスミド組換え体
JPH0227993A (ja) * 1988-07-15 1990-01-30 Nippon Shinyaku Co Ltd ｈＥＧＦの製法
US5223407A (en) * 1988-08-31 1993-06-29 Allelix Inc. Excretion of heterologous proteins from e. coli
AU7779191A (en) * 1990-04-11 1991-10-30 Indu Parikh Method for the purification of epidermal growth factor

Also Published As

Publication number Publication date
US5652120A (en) 1997-07-29
EP0652954A1 (de) 1995-05-17
JPH07509140A (ja) 1995-10-12
AU6582594A (en) 1994-11-21
EP0652954B1 (de) 2001-06-20
WO1994025592A1 (en) 1994-11-10
JP2609515B2 (ja) 1997-05-14
DE69427515T2 (de) 2001-10-04

Similar Documents

Publication Publication Date Title
DE59306172D1 (de) Flammenhydrolytisch hergestelltes Titandioxid-Mischoxid, Verfahren zu seiner Herstellung und Verwendung
DE69417025T2 (de) Geformter vliesstoff und verfahren zu seiner herstellung
DE69331176D1 (de) Knochenzement und Verfahren zu seiner Herstellung
ATE209878T1 (de) Interdentalreiniger und verfahren zu seiner herstellung
DE69530312D1 (de) Stabiles lycopin konzentrat und verfahren zu seiner herstellung
DE3777931D1 (de) Titandioxydsol und verfahren zur seiner herstellung.
DE69711648D1 (de) Antimikrobielle zusammensetzung und verfahren zu ihrere herstellung
DE69511248D1 (de) Polycarbomate, verfahren zur herstellung von polycarbomaten und verfahren zur herstellung von polyisocyanaten
DE69402688D1 (de) Luftfilter und verfahren zu seiner herstellung
DE69422812D1 (de) Verfahren zur herstellung von 1,1,1,3,3-pentafluorpropan und/oder 1,1,3,3,3-pentafluorpropen
DE69618329T2 (de) Künstliches haar für haarimplantate und verfahren zu seiner herstellung
DE69622051D1 (de) Verfahren zur herstellung von 2,4-dihydroxy-pyridin und 2,4-dihydroxy-3-nitropyridin
DE69321848D1 (de) Verfahren zur herstellung von 1,1,1,2,3,3-hexafluorpropan und von tetrafluorchlorpropen
DE59610140D1 (de) Cyclisches dodecapeptid und verfahren zu seiner herstellung
DE69510526T2 (de) Gleitbauteil und Verfahren zu seiner Herstellung
DE69208317D1 (de) Oxidischer supraleiter und verfahren zu seiner herstellung
DE69328243T2 (de) Filter und verfahren zu seiner herstellung
DE69427515T2 (de) Neuartiger genvektor codierend fur den epidermis wachstumsfaktor und verfahren zu seiner herstellung
DE69419516D1 (de) Verfahren zur herstellung von hexafluorocyclobuten und verfahren zur herstellung von hexafluorocyclobutan
DE69424952D1 (de) Hundekauspiel zur zahnpflege und verfahren zu dessen herstellung
DE59304145D1 (de) Gleitelement und verfahren zu seiner herstellung
ATA31296A (de) Schichtkörper und verfahren zu seiner herstellung
DE69814462D1 (de) 1,7-dibromodibenzosuberon und verfahren zur herstellung
ATA221591A (de) Suspensionsaerosolpräparat und verfahren zu seiner herstellung
DE59401694D1 (de) 2-Cyanoethyl-2'-hydroxyethylsulfon, Verfahren zu seiner Herstellung und seine Verwendung zur Herstellung von 3-Aminopropyl-2'-hydroxyethylsulfon

Legal Events

Date Code Title Description
8364 No opposition during term of opposition