DE69331176D1 - Knochenzement und Verfahren zu seiner Herstellung - Google Patents

Knochenzement und Verfahren zu seiner Herstellung

Info

Publication number
DE69331176D1
DE69331176D1 DE69331176T DE69331176T DE69331176D1 DE 69331176 D1 DE69331176 D1 DE 69331176D1 DE 69331176 T DE69331176 T DE 69331176T DE 69331176 T DE69331176 T DE 69331176T DE 69331176 D1 DE69331176 D1 DE 69331176D1
Authority
DE
Germany
Prior art keywords
manufacture
bone cement
cement
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331176T
Other languages
English (en)
Other versions
DE69331176T2 (de
Inventor
Steve T Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Inc
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE69331176D1 publication Critical patent/DE69331176D1/de
Application granted granted Critical
Publication of DE69331176T2 publication Critical patent/DE69331176T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K9/00—Use of pretreated ingredients
    • C08K9/10—Encapsulated ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0089—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
DE69331176T 1992-07-28 1993-07-28 Knochenzement und Verfahren zu seiner Herstellung Expired - Lifetime DE69331176T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/921,030 US5334626A (en) 1992-07-28 1992-07-28 Bone cement composition and method of manufacture

Publications (2)

Publication Number Publication Date
DE69331176D1 true DE69331176D1 (de) 2002-01-03
DE69331176T2 DE69331176T2 (de) 2002-07-11

Family

ID=25444810

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331176T Expired - Lifetime DE69331176T2 (de) 1992-07-28 1993-07-28 Knochenzement und Verfahren zu seiner Herstellung

Country Status (6)

Country Link
US (2) US5334626A (de)
EP (1) EP0581387B1 (de)
JP (2) JPH0678987A (de)
AU (1) AU666191B2 (de)
CA (1) CA2098082C (de)
DE (1) DE69331176T2 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080801A (en) * 1990-09-13 2000-06-27 Klaus Draenert Multi-component material and process for its preparation
KR0139235B1 (ko) * 1994-01-29 1998-04-28 조세현 정형외과용 세멘트 비드조성물 및 그의 제조방법
US20020032298A1 (en) * 1994-07-22 2002-03-14 Bennett Steven L. Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US5578662A (en) 1994-07-22 1996-11-26 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6339130B1 (en) * 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
EP0831756A1 (de) * 1995-06-06 1998-04-01 Merck & Co., Inc. Bisphosphonat-zementzusammensetzung zur verhinderung von aseptischer lockerung orthopädischer prothesen
US5795922A (en) * 1995-06-06 1998-08-18 Clemson University Bone cement composistion containing microencapsulated radiopacifier and method of making same
US5942559A (en) * 1996-08-26 1999-08-24 Ivoclar Ag Dental light-curing opaquer
US5756127A (en) * 1996-10-29 1998-05-26 Wright Medical Technology, Inc. Implantable bioresorbable string of calcium sulfate beads
US5902839A (en) * 1996-12-02 1999-05-11 Northwestern University Bone cement and method of preparation
US6713527B2 (en) 1997-02-07 2004-03-30 Queen's University At Kingston Anaesthetic bone cement
US5847046A (en) * 1997-03-12 1998-12-08 United States Surgical Corporation Biodegradable bone cement
US6309420B1 (en) * 1997-10-14 2001-10-30 Parallax Medical, Inc. Enhanced visibility materials for implantation in hard tissue
US6020396A (en) * 1998-03-13 2000-02-01 The Penn State Research Foundation Bone cement compositions
CA2366377A1 (en) * 1999-03-31 2000-10-05 Brigham And Women's Hospital, Inc. Nanocomposite surgical materials and method of producing them
US7371408B1 (en) 1999-06-07 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
US6273916B1 (en) 1999-09-02 2001-08-14 Cook Incorporated Method and apparatus for strengthening vertebral bodies
WO2002058592A2 (en) * 2001-01-26 2002-08-01 Uab Research Foundation Bone cement and a system for mixing and delivery thereof
US7008433B2 (en) 2001-02-15 2006-03-07 Depuy Acromed, Inc. Vertebroplasty injection device
EP1492475B1 (de) * 2001-04-16 2011-12-21 Wright Medical Technology, Inc. Dichte/poröse strukturen zur verwendung als knochenersatz
ITVI20010126A1 (it) * 2001-05-30 2002-11-30 Tecres Spa Cemento osseo radiopaco per uso ortopedico nonche' metodo di realizzazione
US7371409B2 (en) 2001-09-06 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
AU2003258172B2 (en) 2002-03-29 2008-02-28 Wright Medical Technolgy, Inc. Bone graft substitute composition
US6652887B1 (en) 2002-06-24 2003-11-25 Wright Medical Technology, Inc. Bone graft substitute composition
US7291179B2 (en) 2002-06-24 2007-11-06 Wright Medical Technology, Inc. Bone graft substitute composition
AU2003284924B2 (en) * 2002-10-28 2009-01-08 Covidien Lp Bioabsorbable adhesive compounds
US7507257B2 (en) * 2003-02-04 2009-03-24 Wright Medical Technology, Inc. Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects
ES2545328T3 (es) 2003-03-14 2015-09-10 Depuy Spine, Inc. Dispositivo hidráulico de inyección de cemento óseo en vertebroplastia percutánea
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
IL166017A0 (en) * 2004-12-28 2006-01-15 Disc O Tech Medical Tech Ltd Materials devices and methods for treating bones
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
WO2005030034A2 (en) 2003-09-26 2005-04-07 Depuy Spine, Inc. Device for delivering viscous material
US7829105B2 (en) 2004-03-02 2010-11-09 Nanotherapeutics, Inc. Compositions for repairing bone
US7621952B2 (en) * 2004-06-07 2009-11-24 Dfine, Inc. Implants and methods for treating bone
US20060095138A1 (en) * 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
CN106963464B (zh) 2004-07-30 2019-11-05 德普伊新特斯产品有限责任公司 外科用具
US20060106459A1 (en) * 2004-08-30 2006-05-18 Csaba Truckai Bone treatment systems and methods
DE102004049121B4 (de) * 2004-10-07 2008-01-10 Heraeus Kulzer Gmbh Antibiotikum-/Antibiotika enthaltender PMMA-Knochenzement
US7250550B2 (en) * 2004-10-22 2007-07-31 Wright Medical Technology, Inc. Synthetic bone substitute material
US8048083B2 (en) 2004-11-05 2011-11-01 Dfine, Inc. Bone treatment systems and methods
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
IL174347A0 (en) * 2005-07-31 2006-08-20 Disc O Tech Medical Tech Ltd Bone cement and methods of use thereof
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8540723B2 (en) 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
US8777479B2 (en) 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
DE102005040429A1 (de) * 2005-08-25 2007-03-01 Heraeus Kulzer Gmbh Wirkstofffreisetzungssystem und seine Verwendung
DK1933892T3 (da) * 2005-09-09 2013-03-25 Agnovos Healthcare Llc Sammensat knoglegrafterstatningscement og artikler fremstillet deraf
US8025903B2 (en) 2005-09-09 2011-09-27 Wright Medical Technology, Inc. Composite bone graft substitute cement and articles produced therefrom
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
WO2007089739A2 (en) 2006-01-27 2007-08-09 Stryker Corporation Low pressure delivery system and method for delivering a solid and liquid mixture into a target site for medical treatment
US20070233250A1 (en) * 2006-02-07 2007-10-04 Shadduck John H Systems for treating bone
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
US7981945B2 (en) * 2006-03-01 2011-07-19 Poly-Med, Inc. Antimicrobial, radiopaque, microfiber-reinforced, polymeric methacrylate bone cement
US8685421B2 (en) 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
US9072808B2 (en) * 2006-07-17 2015-07-07 Syracuse University Multi-solution bone cements and methods of making the same
US8383734B2 (en) * 2006-07-17 2013-02-26 Syracuse University Multi-solution bone cements and methods of making the same
US8575274B2 (en) * 2006-07-17 2013-11-05 Syracuse University Multi-solution bone cements and methods of making the same
AU2011226788B2 (en) * 2006-09-14 2013-07-25 Depuy Spine, Inc. Bone Cement and Methods of Use Thereof
CA2663447A1 (en) 2006-09-14 2008-03-20 Depuy Spine, Inc. Polymeric bone cement and methods of use thereof
CA2747850C (en) 2006-10-19 2013-05-14 Depuy Spine, Inc. Fluid delivery system
US20100233225A1 (en) * 2007-02-09 2010-09-16 Bingyun Li Method of surface coating devices to incorporate bioactive molecules
WO2008137428A2 (en) 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
US7883511B2 (en) * 2007-09-12 2011-02-08 Fernyhough Jeffrey C Method and composition for use in reinforcing bone
US8500947B2 (en) 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
US9510885B2 (en) 2007-11-16 2016-12-06 Osseon Llc Steerable and curvable cavity creation system
US20090131886A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system
US20090182427A1 (en) * 2007-12-06 2009-07-16 Osseon Therapeutics, Inc. Vertebroplasty implant with enhanced interfacial shear strength
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
US9445854B2 (en) 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
JP5509098B2 (ja) * 2008-02-28 2014-06-04 ディーエフアイエヌイー・インコーポレーテッド 骨治療システムおよび方法
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
EP2361077A4 (de) * 2008-07-11 2012-09-05 Univ Syracuse Multi-lösungs-knochenzemente und herstellungsverfahren dafür
US20100298832A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable vertebroplasty drill
EP2563233B1 (de) 2010-04-29 2020-04-01 Dfine, Inc. System zur verwendung bei der behandlung von wirbelfrakturen
JP6298468B2 (ja) 2012-10-16 2018-03-20 サーモディクス，インコーポレイテッド 創傷充填デバイスおよび方法
CA2921978A1 (en) 2013-09-30 2015-04-02 Lucite International Speciality Polymers & Resins Limited A hardenable multi-part acrylic composition
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
CN104906640A (zh) * 2015-06-15 2015-09-16 东华大学 一种可显影的生物降解医用捆扎带及其制备方法
WO2018081279A1 (en) 2016-10-27 2018-05-03 Dfine, Inc. Articulating osteotome with cement delivery channel
WO2018098433A1 (en) 2016-11-28 2018-05-31 Dfine, Inc. Tumor ablation devices and related methods
US10470781B2 (en) 2016-12-09 2019-11-12 Dfine, Inc. Medical devices for treating hard tissues and related methods
WO2018129180A1 (en) 2017-01-06 2018-07-12 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
KR102394502B1 (ko) 2017-03-31 2022-05-03 미쓰이 가가쿠 가부시키가이샤 경조직 보수용 조성물 및 경조직 보수용 키트
US11883555B2 (en) 2017-03-31 2024-01-30 Mitsui Chemicals, Inc. Composition for hard tissue repair and kit for hard tissue repair
WO2020097339A1 (en) 2018-11-08 2020-05-14 Dfine, Inc. Tumor ablation device and related systems and methods
US11986229B2 (en) 2019-09-18 2024-05-21 Merit Medical Systems, Inc. Osteotome with inflatable portion and multiwire articulation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3715331A (en) * 1970-05-01 1973-02-06 Coe Labor Monomer soluble x-ray opaque methacrylate particles
US4045403A (en) * 1972-07-19 1977-08-30 General Electric Company Method of compounding thermo-plastic polymeric materials and fillers
US4404327A (en) * 1979-10-31 1983-09-13 Crugnola Aldo M Orthopaedic cement from acrylate polymers
US4341691A (en) * 1980-02-20 1982-07-27 Zimmer, Inc. Low viscosity bone cement
DE3128923A1 (de) * 1981-07-22 1983-02-10 Beiersdorf Ag, 2000 Hamburg Pulvermischung fuer chirurgische zwecke
US4547390A (en) * 1982-03-12 1985-10-15 Medical Biological Sciences, Inc. Process of making implantable prosthesis material of modified polymeric acrylic (PMMA) beads coated with PHEMA and barium sulfate
US4535485A (en) * 1982-03-12 1985-08-20 Medical Biological Sciences, Inc. Polymeric acrylic prothesis
JPS59500453A (ja) * 1982-03-12 1984-03-22 ユナイテイド　ステイツ　サ−ジカル　コ−ポレイシヨン 高分子アクリル人工器官
US4500658A (en) * 1983-06-06 1985-02-19 Austenal International, Inc. Radiopaque acrylic resin
DE3341888A1 (de) * 1983-11-19 1985-05-30 Bayer Ag, 5090 Leverkusen Anorganisch-organische fuellstoffe, verfahren zu deren herstellung sowie deren verwendung in polymerisierbaren massen
US4675140A (en) * 1984-05-18 1987-06-23 Washington University Technology Associates Method for coating particles or liquid droplets
GB8524152D0 (en) * 1985-10-01 1985-11-06 Cole Polymers Ltd Bone cement
DE3674411D1 (de) * 1986-11-19 1990-10-25 Experimentelle Chirurgie Lab Verfahren und apparat zur bereitung eines selbsthaertenden zweikomponenten-pulver-fluessigkeit-knochenzements.
US4837279A (en) * 1988-02-22 1989-06-06 Pfizer Hospital Products Corp, Inc. Bone cement
US5061520A (en) * 1990-10-05 1991-10-29 Kv Pharmaceutical Company Particle enrobing process and apparatus
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer

Also Published As

Publication number Publication date
US5512610A (en) 1996-04-30
JPH0678987A (ja) 1994-03-22
JP2003160372A (ja) 2003-06-03
CA2098082C (en) 2004-11-23
CA2098082A1 (en) 1994-01-29
JP3670637B2 (ja) 2005-07-13
US5334626A (en) 1994-08-02
EP0581387A1 (de) 1994-02-02
AU3984093A (en) 1994-02-03
EP0581387B1 (de) 2001-11-21
DE69331176T2 (de) 2002-07-11
AU666191B2 (en) 1996-02-01

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