DE69423601T2 - Elektrochemische Bestimmungsmethode und neue p-Phenylendiamin-Verbindung - Google Patents

Elektrochemische Bestimmungsmethode und neue p-Phenylendiamin-Verbindung

Info

Publication number
DE69423601T2
DE69423601T2 DE69423601T DE69423601T DE69423601T2 DE 69423601 T2 DE69423601 T2 DE 69423601T2 DE 69423601 T DE69423601 T DE 69423601T DE 69423601 T DE69423601 T DE 69423601T DE 69423601 T2 DE69423601 T2 DE 69423601T2
Authority
DE
Germany
Prior art keywords
substance
specific binding
sample
oxidation
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69423601T
Other languages
German (de)
English (en)
Other versions
DE69423601D1 (de
Inventor
Hideyuki Terasawa
Tadakazu Yamauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69423601D1 publication Critical patent/DE69423601D1/de
Publication of DE69423601T2 publication Critical patent/DE69423601T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/16Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/817Enzyme or microbe electrode
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/806Electrical property or magnetic property

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Secondary Cells (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
DE69423601T 1993-12-29 1994-12-29 Elektrochemische Bestimmungsmethode und neue p-Phenylendiamin-Verbindung Expired - Fee Related DE69423601T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP35337793 1993-12-29

Publications (2)

Publication Number Publication Date
DE69423601D1 DE69423601D1 (de) 2000-04-27
DE69423601T2 true DE69423601T2 (de) 2000-07-06

Family

ID=18430431

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69423601T Expired - Fee Related DE69423601T2 (de) 1993-12-29 1994-12-29 Elektrochemische Bestimmungsmethode und neue p-Phenylendiamin-Verbindung

Country Status (8)

Country Link
US (1) US5609749A (enExample)
EP (1) EP0663446B1 (enExample)
AT (1) ATE191010T1 (enExample)
CA (1) CA2139293A1 (enExample)
DE (1) DE69423601T2 (enExample)
DK (1) DK0663446T3 (enExample)
ES (1) ES2148272T3 (enExample)
PT (1) PT663446E (enExample)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0781850A3 (en) * 1995-12-28 1998-08-12 Mochida Pharmaceutical Co., Ltd. Assay utilizing hydrogen peroxide adduct
US6117290A (en) * 1997-09-26 2000-09-12 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US7494816B2 (en) * 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6294281B1 (en) * 1998-06-17 2001-09-25 Therasense, Inc. Biological fuel cell and method
US6582583B1 (en) 1998-11-30 2003-06-24 The United States Of America As Represented By The Department Of Health And Human Services Amperometric biomimetic enzyme sensors based on modified cyclodextrin as electrocatalysts
GB9905771D0 (en) 1999-03-12 1999-05-05 Isis Innovation Compounds
AU1631101A (en) * 1999-10-07 2001-05-10 Pepex Biomedical, Llc Sensor for measuring a bioanalyte such as lactate
US6464849B1 (en) 1999-10-07 2002-10-15 Pepex Biomedical, L.L.C. Sensor for measuring a bioanalyte such as lactate
EP1124131B1 (en) * 2000-01-27 2008-01-16 Matsushita Electric Industrial Co., Ltd. Biosensor and method of producing the same
FR2805545B1 (fr) * 2000-02-24 2002-05-17 Argene Sa Procede electrochimique de detection d'acides nucleiques
DE10032042A1 (de) * 2000-07-05 2002-01-24 Inventus Biotec Gesellschaft Fuer Innovative Bioanalytik, Biosensoren Und Diagnostika Mbh & Co. Kg Elektrochemischer Einwegbiosensor für die quantitative Bestimmung von Analytkonzentrationen in Flüssigkeiten
JP4184074B2 (ja) * 2000-07-31 2008-11-19 松下電器産業株式会社 バイオセンサ
JP4184073B2 (ja) * 2000-07-31 2008-11-19 松下電器産業株式会社 バイオセンサ
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
JP4183902B2 (ja) * 2000-12-27 2008-11-19 松下電器産業株式会社 バイオセンサ
US7005273B2 (en) * 2001-05-16 2006-02-28 Therasense, Inc. Method for the determination of glycated hemoglobin
JP4213361B2 (ja) * 2001-05-22 2009-01-21 パナソニック株式会社 バイオセンサ
AU2002315177A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
WO2002100254A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
WO2002100461A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
EP1406537B1 (en) 2001-06-12 2011-01-12 Pelikan Technologies Inc. Integrated blood sampling analysis system with multi-use sampling module
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7981056B2 (en) * 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
CA2448790C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Electric lancet actuator
ATE450209T1 (de) 2001-06-12 2009-12-15 Pelikan Technologies Inc Gerät und verfahren zur entnahme von blutproben
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
WO2003042680A1 (en) * 2001-11-14 2003-05-22 Matsushita Electric Industrial Co., Ltd. Biosensor
JPWO2003048756A1 (ja) * 2001-12-05 2005-04-14 松下電器産業株式会社 バイオセンサ
US7648468B2 (en) * 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7909778B2 (en) * 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7244265B2 (en) 2002-04-19 2007-07-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7485128B2 (en) 2002-04-19 2009-02-03 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7258693B2 (en) 2002-04-19 2007-08-21 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7368190B2 (en) * 2002-05-02 2008-05-06 Abbott Diabetes Care Inc. Miniature biological fuel cell that is operational under physiological conditions, and associated devices and methods
CA2499527A1 (en) * 2002-09-20 2004-04-01 Medinnov, Inc. An analyzer for the simultaneous enzymatic detection of closely related analytes
US7265881B2 (en) * 2002-12-20 2007-09-04 Hewlett-Packard Development Company, L.P. Method and apparatus for measuring assembly and alignment errors in sensor assemblies
WO2004061418A2 (en) * 2002-12-26 2004-07-22 Meso Scale Technologies, Llc. Assay cartridges and methods of using the same
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US20040211702A1 (en) * 2003-04-24 2004-10-28 General Electric Company Water-soluble phenylenediamine compositions and methods for stabilizing ethylenically unsaturated compounds and monomers
EP1628567B1 (en) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Method and apparatus for fluid injection
JP4839569B2 (ja) 2003-06-05 2011-12-21 ソニー株式会社 酵素固定化電極およびその製造方法ならびに電極反応利用装置およびその製造方法
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
WO2004112602A1 (en) 2003-06-13 2004-12-29 Pelikan Technologies, Inc. Method and apparatus for a point of care device
EP1634066B1 (en) * 2003-06-17 2016-08-24 Chun-Mu Huang Structure and manufacturing method of disposable electrochemical sensor strip
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8628690B2 (en) * 2004-02-23 2014-01-14 The Texas A&M University System Nanoemulsion compositions and methods of use thereof
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US9044178B2 (en) * 2007-08-30 2015-06-02 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
WO2009032760A2 (en) 2007-08-30 2009-03-12 Pepex Biomedical Llc Electrochmical sensor and method for manufacturing
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
WO2010056876A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Manufacturing electrochemical sensor module
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100213057A1 (en) * 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
EP2418479B1 (en) 2009-04-07 2013-10-23 Panasonic Corporation Sensor chip and measuring device and blood test device in which this sensor chip is used
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9110053B2 (en) * 2010-08-20 2015-08-18 Agilent Technologies, Inc. Dried blood spotting paper device and method
US9585605B2 (en) 2011-05-19 2017-03-07 Pepex Biomedical, Inc. Fluid management and patient monitoring system
US9504162B2 (en) 2011-05-20 2016-11-22 Pepex Biomedical, Inc. Manufacturing electrochemical sensor modules
EP2925229A4 (en) 2012-12-03 2017-01-25 Pepex Biomedical, Inc. Sensor module and method of using a sensor module
EP3152559B1 (en) 2014-06-04 2020-12-02 Pepex Biomedical, Inc. Electrochemical sensors made using advanced printing technology
EP3418730A4 (en) * 2016-02-16 2019-10-30 Seikagaku Corporation ELECTROCHEMICAL MEASUREMENT USING A PHENYLENEDIAMINE DERIVATIVE
GB2566516A (en) 2017-09-15 2019-03-20 Univ Oxford Innovation Ltd Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria
KR102083421B1 (ko) * 2018-05-04 2020-03-02 전자부품연구원 소변 내 바이오마커의 농도를 전기화학적으로 측정하는 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3921554A1 (de) * 1989-06-30 1991-01-17 Henkel Kgaa Klebestift mit verbesserter klebkraft
DE4003194A1 (de) * 1990-02-03 1991-08-08 Boehringer Mannheim Gmbh Verfahren und sensorelektrodensystem zur elektrochemischen bestimmung eines analyts oder einer oxidoreduktase sowie verwendung hierfuer geeigneter verbindungen
US5286362A (en) * 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
DE69120956T2 (de) * 1990-10-10 1997-01-23 Novonordisk As Verwendung von benzenderivaten als charge-transfer-mediatoren
US5182213A (en) * 1991-03-18 1993-01-26 Miles Inc. Method for detecting the presence of peroxidatively active substance in basic media
CA2074752A1 (en) * 1991-07-29 1993-01-30 Tadakazu Yamauchi Process and device for specific binding assay

Also Published As

Publication number Publication date
ATE191010T1 (de) 2000-04-15
DK0663446T3 (da) 2000-10-23
CA2139293A1 (en) 1995-06-30
EP0663446A3 (enExample) 1995-08-30
EP0663446A2 (en) 1995-07-19
ES2148272T3 (es) 2000-10-16
DE69423601D1 (de) 2000-04-27
EP0663446B1 (en) 2000-03-22
US5609749A (en) 1997-03-11
PT663446E (pt) 2000-06-30

Similar Documents

Publication Publication Date Title
DE69423601T2 (de) Elektrochemische Bestimmungsmethode und neue p-Phenylendiamin-Verbindung
DE69219686T2 (de) Verfahren und Vorrichtung zur Verwendung in spezifischen Bindungstests
DE2660548C2 (de) Konjugate für ein heterogenes spezifisches Bindungsverfahren zur Bestimmung eines Liganden in einem flüssigen Medium
DE2754086C3 (de) Spezifisches Bindungsverfahren zum Nachweis und zur Bestimmung eines Liganden in einem flüssigen Medium
DE3785499T2 (de) Verwendung von Phenolen und Anilinen zur Erhöhung der Rate von peroxidase-katalysierter Oxydation der Leucofarbstoffe.
DE3587720T2 (de) Testverfahren.
DE3705686C2 (de) Verfahren zur Bestimmung von Antikörpern
DE69427333T2 (de) Trockene Elemente, Testgeräte und-ausstattungen sowie Verfahren zum Bestimmen vn Peroxidasemarkieren Analyten mit Hilfe von Chemiluminescenz-Reagenzsystemen
DE3329728A1 (de) Immunotest
EP0809111A2 (de) Bestimmungsverfahren mit oligomerisierten Rezeptoren
DE10032042A1 (de) Elektrochemischer Einwegbiosensor für die quantitative Bestimmung von Analytkonzentrationen in Flüssigkeiten
EP0423632B1 (de) Hydrolase-Substrate
EP1637882A1 (de) Lateralflussmessvorrichtung und Messverfahren für Analyten
DE69328013T2 (de) Immunoassay unter Verwendung eines 4-Hydroxy- oder 4-Alkoxyacetamides als Stabilisator
DE69636013T2 (de) Verfahren zum erlangen von rezeptor-freigabeligand (reland)-komplexen und testansätze
DE2365610A1 (de) Neue substituierte propan- oder butanderivate
DE69927240T2 (de) Messung von hydriden mit hilfe chemilumineszierender acridiniumverbindungen
DE69530148T2 (de) Analytisches Element, Zusammensetzung und Verfahren unter Verwendung von modifizierter Apo-Meerrettich-Peroxidase
JPH07234201A (ja) 電気化学的測定方法および新規p−フェニレンジアミン化合物
CH659713A5 (de) Spezifisches bindungs-testverfahren und reagenszusammensetzung zur durchfuehrung dieses verfahrens.
DD249768A5 (de) Verfahren zur bestimmung eines partners einer immunreaktion
DE69607972T2 (de) Analytisches element und verfahren zur bestimmung eines spezifischen bindenden liganden unter verwendung einer vanadin-bromperoxidase als ein signalgenerierendes enzym
DE19828378A1 (de) Farbe entwickelndes Verfahren, Enzym-Immunoassay, der das Farbe entwickelnde Verfahren anwendet und Immunochromatographie, die den Enzym-Immunoassay einarbeitet
DE69822446T2 (de) Cyclosporin derivate und deren verwendung
EP0006998B1 (de) Verfahren zur Bestimmung des Thyroxin-bindungsindex im Serum und Testkit zur Durchführung des Verfahrens

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee