DE69411616T2 - Triazolopyridazin-Derivate, ihre Herstellung und Verwendung - Google Patents

Triazolopyridazin-Derivate, ihre Herstellung und Verwendung

Info

Publication number
DE69411616T2
DE69411616T2 DE69411616T DE69411616T DE69411616T2 DE 69411616 T2 DE69411616 T2 DE 69411616T2 DE 69411616 T DE69411616 T DE 69411616T DE 69411616 T DE69411616 T DE 69411616T DE 69411616 T2 DE69411616 T2 DE 69411616T2
Authority
DE
Germany
Prior art keywords
group
atom
lower alkyl
hydrogen atom
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69411616T
Other languages
English (en)
Other versions
DE69411616D1 (de
Inventor
Akio Miyake
Masahiro Kajino
Yasuko Ashida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69411616D1 publication Critical patent/DE69411616D1/de
Application granted granted Critical
Publication of DE69411616T2 publication Critical patent/DE69411616T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69411616T 1993-04-12 1994-04-11 Triazolopyridazin-Derivate, ihre Herstellung und Verwendung Expired - Fee Related DE69411616T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11004293 1993-04-12

Publications (2)

Publication Number Publication Date
DE69411616D1 DE69411616D1 (de) 1998-08-20
DE69411616T2 true DE69411616T2 (de) 1998-11-19

Family

ID=14525644

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69411616T Expired - Fee Related DE69411616T2 (de) 1993-04-12 1994-04-11 Triazolopyridazin-Derivate, ihre Herstellung und Verwendung

Country Status (5)

Country Link
US (1) US5492909A (de)
EP (1) EP0620224B1 (de)
AT (1) ATE168376T1 (de)
CA (1) CA2120997A1 (de)
DE (1) DE69411616T2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9507348D0 (en) * 1995-04-08 1995-05-31 Knoll Ag Therapeutic agents
AU7079998A (en) 1997-04-25 1998-11-24 Takeda Chemical Industries Ltd. Condensed pyridazine derivatives, their production and use
US6303597B1 (en) 1998-01-14 2001-10-16 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for GABA receptors
WO2000020417A1 (fr) 1998-10-06 2000-04-13 Takeda Chemical Industries, Ltd. Composes de pyridazine condenses, leur procede de preparation et leur utilisation
DE69913558T2 (de) 1998-10-21 2004-11-04 Takeda Chemical Industries, Ltd. Kondensierte pyridazinderivate, verfahren zu ihrer herstellung und ihre anwendung
IT1303272B1 (it) * 1998-10-29 2000-11-06 Zambon Spa Derivati triciclici inibitori della fosfodiesterasi 4
CN102791715B (zh) 2009-12-31 2016-04-27 卡洛斯三世国家癌症研究中心基金会 用作激酶抑制剂的三环化合物
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
WO2013005057A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) New compounds
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
WO2013005041A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Tricyclic heterocyclic compounds as kinase inhibitors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3915968A (en) * 1973-09-21 1975-10-28 Lepetit Spa Triazolopyridazines
US4136182A (en) * 1976-05-26 1979-01-23 The Dow Chemical Company Triazolopyridazines used to alleviate bronchial spasms
AU593109B2 (en) * 1986-06-05 1990-02-01 Merrell Dow Pharmaceuticals Inc. 2,3-dihydro-1-(8-methyl-1,2,4-triazolo-{4,3-b}pyridazin-6-YL )-4(1H)-pyridinone
JP3115575B2 (ja) * 1989-01-31 2000-12-11 武田薬品工業株式会社 イミダゾピリダジン誘導体、その用途及び製造法
PH27291A (en) * 1989-01-31 1993-05-04 Takeda Chemical Industries Ltd Imidazolpyrimidazines their production and use
EP0440119A1 (de) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Imidazopyridazinverbindungen, ihre Herstellung und Verwendung
US5011835A (en) * 1990-02-07 1991-04-30 Merrell Dow Pharmaceuticals Inc. Substituted triazolopyridazines, pharmaceutical compositions and use
ATE117690T1 (de) * 1990-03-01 1995-02-15 Takeda Chemical Industries Ltd Imidazopyridazine, ihre herstellung und verwendung.
TW211013B (de) * 1991-12-27 1993-08-11 Takeda Pharm Industry Co Ltd
LT3200B (en) * 1992-03-18 1995-03-27 Takeda Chemical Industries Ltd Triazolopyridazine methodfor production thereof and use
DE69322673T2 (de) * 1992-03-18 1999-05-06 Takeda Chemical Industries Ltd Imidazopyridazine als Antiasthmatika

Also Published As

Publication number Publication date
US5492909A (en) 1996-02-20
DE69411616D1 (de) 1998-08-20
CA2120997A1 (en) 1994-10-13
EP0620224B1 (de) 1998-07-15
EP0620224A1 (de) 1994-10-19
ATE168376T1 (de) 1998-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee