ATE168376T1 - Triazolopyridazin-derivate, ihre herstellung und verwendung - Google Patents
Triazolopyridazin-derivate, ihre herstellung und verwendungInfo
- Publication number
- ATE168376T1 ATE168376T1 AT94105542T AT94105542T ATE168376T1 AT E168376 T1 ATE168376 T1 AT E168376T1 AT 94105542 T AT94105542 T AT 94105542T AT 94105542 T AT94105542 T AT 94105542T AT E168376 T1 ATE168376 T1 AT E168376T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- atom
- lower alkyl
- hydrogen atom
- alkyl group
- Prior art date
Links
- CBHTTYDJRXOHHL-UHFFFAOYSA-N 2h-triazolo[4,5-c]pyridazine Chemical class N1=NC=CC2=C1N=NN2 CBHTTYDJRXOHHL-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 2
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11004293 | 1993-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE168376T1 true ATE168376T1 (de) | 1998-08-15 |
Family
ID=14525644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94105542T ATE168376T1 (de) | 1993-04-12 | 1994-04-11 | Triazolopyridazin-derivate, ihre herstellung und verwendung |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5492909A (de) |
| EP (1) | EP0620224B1 (de) |
| AT (1) | ATE168376T1 (de) |
| CA (1) | CA2120997A1 (de) |
| DE (1) | DE69411616T2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9507348D0 (en) * | 1995-04-08 | 1995-05-31 | Knoll Ag | Therapeutic agents |
| EP0979231B1 (de) | 1997-04-25 | 2004-11-24 | Takeda Chemical Industries, Ltd. | Condensierte pyridazine derivate,deren herstellung und verwendung |
| CA2315219A1 (en) * | 1998-01-14 | 1999-07-22 | Merck Sharp & Dohme Limited | Triazolo-pyridazine derivatives as ligands for gaba receptors |
| CA2346659A1 (en) | 1998-10-06 | 2000-04-13 | Michiyo Gyoten | Condensed pyridazine compounds, their production and use |
| WO2000023450A1 (en) | 1998-10-21 | 2000-04-27 | Takeda Chemical Industries, Ltd. | Fused pyridazine derivatives, process for the preparation of the same and uses thereof |
| IT1303272B1 (it) * | 1998-10-29 | 2000-11-06 | Zambon Spa | Derivati triciclici inibitori della fosfodiesterasi 4 |
| PH12012501361A1 (en) | 2009-12-31 | 2012-10-22 | Centro Nac De Investigaciones Oncologicas Cnio | Tricyclic compounds for use as kinase inhibitors |
| WO2012098387A1 (en) | 2011-01-18 | 2012-07-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors |
| WO2013005057A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | New compounds |
| WO2013004984A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Tricyclic compounds for use as kinase inhibitors |
| WO2013005041A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Tricyclic heterocyclic compounds as kinase inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3915968A (en) * | 1973-09-21 | 1975-10-28 | Lepetit Spa | Triazolopyridazines |
| US4136182A (en) * | 1976-05-26 | 1979-01-23 | The Dow Chemical Company | Triazolopyridazines used to alleviate bronchial spasms |
| FI85481C (fi) * | 1986-06-05 | 1992-04-27 | Merrell Dow Pharma | Foerfarande foer framstaellning av 2,3 -dihydro-1-(8-metyl-1,2,4-triazolo/4,3-b/pyridazin-6-yl)-4(1h) -pyridinon. |
| PH27291A (en) * | 1989-01-31 | 1993-05-04 | Takeda Chemical Industries Ltd | Imidazolpyrimidazines their production and use |
| JP3115575B2 (ja) * | 1989-01-31 | 2000-12-11 | 武田薬品工業株式会社 | イミダゾピリダジン誘導体、その用途及び製造法 |
| EP0440119A1 (de) * | 1990-01-31 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Imidazopyridazinverbindungen, ihre Herstellung und Verwendung |
| US5011835A (en) * | 1990-02-07 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Substituted triazolopyridazines, pharmaceutical compositions and use |
| EP0444549B1 (de) * | 1990-03-01 | 1995-01-25 | Takeda Chemical Industries, Ltd. | Imidazopyridazine, ihre Herstellung und Verwendung |
| TW211013B (de) * | 1991-12-27 | 1993-08-11 | Takeda Pharm Industry Co Ltd | |
| EP0562440B1 (de) * | 1992-03-18 | 1998-12-23 | Takeda Chemical Industries, Ltd. | Imidazopyridazine als Antiasthmatika |
| LT3200B (en) * | 1992-03-18 | 1995-03-27 | Takeda Chemical Industries Ltd | Triazolopyridazine methodfor production thereof and use |
-
1994
- 1994-04-11 AT AT94105542T patent/ATE168376T1/de active
- 1994-04-11 EP EP94105542A patent/EP0620224B1/de not_active Expired - Lifetime
- 1994-04-11 DE DE69411616T patent/DE69411616T2/de not_active Expired - Fee Related
- 1994-04-11 CA CA002120997A patent/CA2120997A1/en not_active Abandoned
- 1994-04-12 US US08/225,981 patent/US5492909A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2120997A1 (en) | 1994-10-13 |
| EP0620224B1 (de) | 1998-07-15 |
| DE69411616T2 (de) | 1998-11-19 |
| DE69411616D1 (de) | 1998-08-20 |
| EP0620224A1 (de) | 1994-10-19 |
| US5492909A (en) | 1996-02-20 |
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