DE69322720T2 - Verfahren zur Herstellung von Biotin - Google Patents
Verfahren zur Herstellung von BiotinInfo
- Publication number
- DE69322720T2 DE69322720T2 DE69322720T DE69322720T DE69322720T2 DE 69322720 T2 DE69322720 T2 DE 69322720T2 DE 69322720 T DE69322720 T DE 69322720T DE 69322720 T DE69322720 T DE 69322720T DE 69322720 T2 DE69322720 T2 DE 69322720T2
- Authority
- DE
- Germany
- Prior art keywords
- biotin
- production
- ability
- disclosed
- medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title abstract 10
- 229960002685 biotin Drugs 0.000 title abstract 5
- 235000020958 biotin Nutrition 0.000 title abstract 5
- 239000011616 biotin Substances 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 241000736131 Sphingomonas Species 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
- C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24174892 | 1992-09-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69322720D1 DE69322720D1 (de) | 1999-02-04 |
| DE69322720T2 true DE69322720T2 (de) | 1999-07-08 |
Family
ID=17078957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69322720T Expired - Lifetime DE69322720T2 (de) | 1992-09-10 | 1993-09-08 | Verfahren zur Herstellung von Biotin |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5432067A (de) |
| EP (1) | EP0589285B1 (de) |
| JP (1) | JP3428078B2 (de) |
| KR (1) | KR100297619B1 (de) |
| CN (1) | CN1050153C (de) |
| AT (1) | ATE174966T1 (de) |
| DE (1) | DE69322720T2 (de) |
| DK (1) | DK0589285T3 (de) |
| ES (1) | ES2126619T3 (de) |
| HU (1) | HU215083B (de) |
| TW (1) | TW255913B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4329129B2 (ja) | 1997-03-03 | 2009-09-09 | 住友化学株式会社 | ビオチン生合成遺伝子を含むｄｎａ断片およびその利用 |
| US6825016B1 (en) * | 1999-04-12 | 2004-11-30 | Arkray, Inc. | α-glycated amino acid releasing enzyme |
| WO2008108674A1 (en) | 2007-03-08 | 2008-09-12 | Biotrend - Inovação E Engenharia Em Biotecnologia, Sa | Production op high- purity carotenoids by fermenting selected bacterial strains |
| CN102491908A (zh) * | 2011-12-16 | 2012-06-13 | 华东理工大学 | 一种生物素生产废水中手性胺的回收方法 |
| KR102130241B1 (ko) | 2019-01-09 | 2020-07-03 | 강명구 | 빙상용 썰매 |
| US20220348974A1 (en) * | 2019-09-09 | 2022-11-03 | Albert Einstein College Of Medicine | Biotin synthases for efficient production of biotin |
| KR20230070943A (ko) * | 2021-11-15 | 2023-05-23 | 씨제이제일제당 (주) | 바이오틴 신타제 활성을 갖는 폴리펩티드 변이체 및 이를 이용한 바이오틴 생산 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3393129A (en) * | 1964-12-23 | 1968-07-16 | Takeda Chemical Industries Ltd | Method for producing d-biotin |
| HU168313B (de) * | 1972-06-13 | 1976-03-28 | ||
| JPS56160998A (en) * | 1980-05-15 | 1981-12-11 | Nippon Zeon Co Ltd | Production of biotin active substance biotin vitamer |
| CA1322735C (en) * | 1987-11-07 | 1993-10-05 | Shinichiro Haze | Microorganism having low acetate forming capability, and process for production of useful substrate using same |
| JP2722504B2 (ja) * | 1988-07-14 | 1998-03-04 | 田辺製薬株式会社 | 新規微生物及びそれを用いるｄ−ビオチンの製法 |
| CN1053217C (zh) * | 1990-03-27 | 2000-06-07 | 资生堂株式会社 | 新的微生物以及利用这些微生物生产生物素同效维生素的方法 |
| JP3006847B2 (ja) * | 1990-03-27 | 2000-02-07 | 株式会社資生堂 | 新規微生物およびそれを用いるビオチン類の製造方法 |
| DE4106375A1 (de) * | 1991-02-28 | 1992-09-03 | Degussa | Eine l-carnitin-amidase produzierender mikroorganismus, l-carnitin-amidase, verfahren zu deren gewinnung und deren verwendung |
-
1993
- 1993-07-19 JP JP17806393A patent/JP3428078B2/ja not_active Expired - Fee Related
- 1993-08-24 TW TW082106811A patent/TW255913B/zh active
- 1993-08-25 US US08/111,440 patent/US5432067A/en not_active Expired - Lifetime
- 1993-09-08 DK DK93114418T patent/DK0589285T3/da active
- 1993-09-08 EP EP93114418A patent/EP0589285B1/de not_active Expired - Lifetime
- 1993-09-08 ES ES93114418T patent/ES2126619T3/es not_active Expired - Lifetime
- 1993-09-08 DE DE69322720T patent/DE69322720T2/de not_active Expired - Lifetime
- 1993-09-08 AT AT93114418T patent/ATE174966T1/de not_active IP Right Cessation
- 1993-09-09 CN CN93116830A patent/CN1050153C/zh not_active Expired - Lifetime
- 1993-09-10 KR KR1019930018253A patent/KR100297619B1/ko not_active IP Right Cessation
- 1993-09-10 HU HU9302568A patent/HU215083B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0589285A2 (de) | 1994-03-30 |
| ES2126619T3 (es) | 1999-04-01 |
| HU9302568D0 (en) | 1993-11-29 |
| HU215083B (hu) | 1998-09-28 |
| EP0589285B1 (de) | 1998-12-23 |
| DE69322720D1 (de) | 1999-02-04 |
| HUT67685A (en) | 1995-04-28 |
| DK0589285T3 (da) | 1999-08-23 |
| CN1050153C (zh) | 2000-03-08 |
| CN1084217A (zh) | 1994-03-23 |
| KR940007188A (ko) | 1994-04-26 |
| EP0589285A3 (de) | 1995-02-15 |
| ATE174966T1 (de) | 1999-01-15 |
| US5432067A (en) | 1995-07-11 |
| TW255913B (de) | 1995-09-01 |
| KR100297619B1 (ko) | 2001-10-24 |
| JPH06133790A (ja) | 1994-05-17 |
| JP3428078B2 (ja) | 2003-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE347607T1 (de) | Verfahren zur herstellung von decosahexaensäure und decosapentsäure | |
| DE69837041D1 (de) | Verfahren und mikroorganism zur herstellung von purin-nukleosiden durch fermentation | |
| DE69114311D1 (de) | Verfahren zur Herstellung und Extrahierung von Antioxydantien aus einer Mikroorganismenkultur und Fotobioreaktor zur Durchführung des Verfahrens. | |
| HUP9801420A2 (hu) | Eljárás L-aminosavak előállítására fermentálással | |
| DE69519638T2 (de) | Verfahren zur Herstellung von Alpha-Hydroxysäuren oder Alpha-Hydroxyamiden durch Mikroorganismen | |
| DE69322720T2 (de) | Verfahren zur Herstellung von Biotin | |
| DE3878747D1 (de) | Verfahren zur herstellung von 2-keto-l-gulonsaeure. | |
| ATE176803T1 (de) | Mikrobielles verfahren zur herstellung von trans- 4-hydroxy-l-prolin | |
| DE69522876T2 (de) | Verfahren zur Herstellung von L-leucin | |
| DE69222150T2 (de) | Prozess zur produktion von cyclosporin-a und/oder c | |
| ATE125570T1 (de) | Biokatalytisches verfahren zur herstellung von l- (-)-carnitin aus crotonobetain und stämme von proteeae zur verwendung in diesem verfahren. | |
| DE69530959D1 (de) | Verfahren zur Herstellung einer L-Aminosäure | |
| ATE2339T1 (de) | Verfahren zur herstellung von sphingomyelinase, sphingomyelinase und deren verwendung. | |
| ATE248225T1 (de) | Verfahren zur herstellung von (s)-3-halogeno-1,2- propandiol durch pseudomonas | |
| ATE355386T1 (de) | Verfahren zur herstellung von l-glutaminsäure durch kontinuierliche gärung | |
| ATE2548T1 (de) | Verfahren zur gewinnung von cholesterinesterase. | |
| ATE95568T1 (de) | Mikrobiologisches verfahren zur herstellung von uk-61.689 und mikroorganismen zur verwendung darin. | |
| EP0455170A3 (en) | Process for culturing microorganisms of the genus pseudomonas and process for producing l-alanine using said microorganisms | |
| ATE194646T1 (de) | H. pylori fermentation verfahren | |
| DE69419592D1 (de) | Verfahren zur Herstellung von Pilocarpin | |
| ATE462010T1 (de) | Verfahren zur herstellung von (r)-1,2-propandiol mittels mikroben | |
| DE60035494D1 (de) | Verfahren zur herstellung von pseudomycin aus pseudomonas syringae | |
| ATE191508T1 (de) | Mikrobiologisches verfahren zur herstellung von 1-ungesättigten, 17-beta-carboxysubstituierten 3- oxo-4-azaandrostan-3-onen | |
| ATE235427T1 (de) | Verfahren zur verringerung der wirkung von reinigunsmitteln auf die keimung und/oder das wachstum von mikroorganismen | |
| DE59208669D1 (de) | Verfahren zur Herstellung von MA |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SUMITOMO CHEMICAL CO. LTD., TOKIO/TOKYO, JP |