ES2126619T3 - Procedimiento de preparacion de biotina. - Google Patents
Procedimiento de preparacion de biotina.Info
- Publication number
- ES2126619T3 ES2126619T3 ES93114418T ES93114418T ES2126619T3 ES 2126619 T3 ES2126619 T3 ES 2126619T3 ES 93114418 T ES93114418 T ES 93114418T ES 93114418 T ES93114418 T ES 93114418T ES 2126619 T3 ES2126619 T3 ES 2126619T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation procedure
- biotin
- biotin preparation
- biotine
- sphingomonas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title abstract 8
- 235000020958 biotin Nutrition 0.000 title abstract 3
- 239000011616 biotin Substances 0.000 title abstract 3
- 229960002685 biotin Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 235000000638 D-biotin Nutrition 0.000 abstract 2
- 239000011665 D-biotin Substances 0.000 abstract 2
- 241000736131 Sphingomonas Species 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
- C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
SE PRESENTA UN PROCESO PARA LA PRODUCCION DE BIOTINA EN EL CUAL SE PREPARA UN CULTIVO DE MICROORGANISMOS DEL GENERO "SPHINGOMONAS", QUE TIENEN LA CAPACIDAD DE PRODUCIR BIOTINA, EN UN MEDIO ADECUADO, Y SE RECOGE LA BIOTINA PRODUCIDA Y ACUMULADA EN EL MEDIO. TAMBIEN SE PRESENTAN MICROORGANISMOS DEL GENERO "SPHINGOMONAS" QUE TIENEN LA CAPACIDAD DE PRODUCIR BIOTINA, QUE SON UTILES PARA ESTE PROCESO DE PRODUCCION DE LA PRESENTE INVENCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24174892 | 1992-09-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2126619T3 true ES2126619T3 (es) | 1999-04-01 |
Family
ID=17078957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93114418T Expired - Lifetime ES2126619T3 (es) | 1992-09-10 | 1993-09-08 | Procedimiento de preparacion de biotina. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5432067A (es) |
EP (1) | EP0589285B1 (es) |
JP (1) | JP3428078B2 (es) |
KR (1) | KR100297619B1 (es) |
CN (1) | CN1050153C (es) |
AT (1) | ATE174966T1 (es) |
DE (1) | DE69322720T2 (es) |
DK (1) | DK0589285T3 (es) |
ES (1) | ES2126619T3 (es) |
HU (1) | HU215083B (es) |
TW (1) | TW255913B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4329129B2 (ja) | 1997-03-03 | 2009-09-09 | 住友化学株式会社 | ビオチン生合成遺伝子を含むdna断片およびその利用 |
WO2000061732A1 (en) * | 1999-04-12 | 2000-10-19 | Arkray, Inc. | α-GLYCATED AMINO ACID RELEASING ENZYME |
WO2008108674A1 (en) | 2007-03-08 | 2008-09-12 | Biotrend - Inovação E Engenharia Em Biotecnologia, Sa | Production op high- purity carotenoids by fermenting selected bacterial strains |
CN102491908A (zh) * | 2011-12-16 | 2012-06-13 | 华东理工大学 | 一种生物素生产废水中手性胺的回收方法 |
KR102130241B1 (ko) | 2019-01-09 | 2020-07-03 | 강명구 | 빙상용 썰매 |
WO2021050371A1 (en) * | 2019-09-09 | 2021-03-18 | Albert Einstein College Of Medicine | Biotin synthases for efficient production of biotin |
KR20230070943A (ko) * | 2021-11-15 | 2023-05-23 | 씨제이제일제당 (주) | 바이오틴 신타제 활성을 갖는 폴리펩티드 변이체 및 이를 이용한 바이오틴 생산 방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3393129A (en) * | 1964-12-23 | 1968-07-16 | Takeda Chemical Industries Ltd | Method for producing d-biotin |
HU168313B (es) * | 1972-06-13 | 1976-03-28 | ||
JPS56160998A (en) * | 1980-05-15 | 1981-12-11 | Nippon Zeon Co Ltd | Production of biotin active substance biotin vitamer |
CA1322735C (en) * | 1987-11-07 | 1993-10-05 | Shinichiro Haze | Microorganism having low acetate forming capability, and process for production of useful substrate using same |
JP2722504B2 (ja) * | 1988-07-14 | 1998-03-04 | 田辺製薬株式会社 | 新規微生物及びそれを用いるd−ビオチンの製法 |
CN1053217C (zh) * | 1990-03-27 | 2000-06-07 | 资生堂株式会社 | 新的微生物以及利用这些微生物生产生物素同效维生素的方法 |
JP3006847B2 (ja) * | 1990-03-27 | 2000-02-07 | 株式会社資生堂 | 新規微生物およびそれを用いるビオチン類の製造方法 |
DE4106375A1 (de) * | 1991-02-28 | 1992-09-03 | Degussa | Eine l-carnitin-amidase produzierender mikroorganismus, l-carnitin-amidase, verfahren zu deren gewinnung und deren verwendung |
-
1993
- 1993-07-19 JP JP17806393A patent/JP3428078B2/ja not_active Expired - Fee Related
- 1993-08-24 TW TW082106811A patent/TW255913B/zh active
- 1993-08-25 US US08/111,440 patent/US5432067A/en not_active Expired - Lifetime
- 1993-09-08 EP EP93114418A patent/EP0589285B1/en not_active Expired - Lifetime
- 1993-09-08 DE DE69322720T patent/DE69322720T2/de not_active Expired - Lifetime
- 1993-09-08 DK DK93114418T patent/DK0589285T3/da active
- 1993-09-08 AT AT93114418T patent/ATE174966T1/de not_active IP Right Cessation
- 1993-09-08 ES ES93114418T patent/ES2126619T3/es not_active Expired - Lifetime
- 1993-09-09 CN CN93116830A patent/CN1050153C/zh not_active Expired - Lifetime
- 1993-09-10 KR KR1019930018253A patent/KR100297619B1/ko not_active IP Right Cessation
- 1993-09-10 HU HU9302568A patent/HU215083B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR940007188A (ko) | 1994-04-26 |
DE69322720T2 (de) | 1999-07-08 |
EP0589285A2 (en) | 1994-03-30 |
HU215083B (hu) | 1998-09-28 |
KR100297619B1 (ko) | 2001-10-24 |
JPH06133790A (ja) | 1994-05-17 |
EP0589285B1 (en) | 1998-12-23 |
DE69322720D1 (de) | 1999-02-04 |
CN1084217A (zh) | 1994-03-23 |
JP3428078B2 (ja) | 2003-07-22 |
CN1050153C (zh) | 2000-03-08 |
TW255913B (es) | 1995-09-01 |
US5432067A (en) | 1995-07-11 |
DK0589285T3 (da) | 1999-08-23 |
HUT67685A (en) | 1995-04-28 |
HU9302568D0 (en) | 1993-11-29 |
ATE174966T1 (de) | 1999-01-15 |
EP0589285A3 (en) | 1995-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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