KR940007188A - 비오틴의 제조방법 - Google Patents

비오틴의 제조방법 Download PDF

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Publication number
KR940007188A
KR940007188A KR1019930018253A KR930018253A KR940007188A KR 940007188 A KR940007188 A KR 940007188A KR 1019930018253 A KR1019930018253 A KR 1019930018253A KR 930018253 A KR930018253 A KR 930018253A KR 940007188 A KR940007188 A KR 940007188A
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KR
South Korea
Prior art keywords
biotin
microorganism
production capacity
spingomonas
medium
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KR1019930018253A
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English (en)
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KR100297619B1 (ko
Inventor
가즈오 구마가이
미사오 미끼
에미꼬 가와노
사또시 미쓰다
Original Assignee
고사이 아끼오
스미또모가가꾸고오교 가부시끼가이샤
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Application filed by 고사이 아끼오, 스미또모가가꾸고오교 가부시끼가이샤 filed Critical 고사이 아끼오
Publication of KR940007188A publication Critical patent/KR940007188A/ko
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Publication of KR100297619B1 publication Critical patent/KR100297619B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
    • C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

비오틴 생산 능력을 갖는스핀고모나스속 미생물의 배양액을 배지에 제조하고, 배지에 생산되고 축적된 비오틴을 수집하는 것으로 구성된 비오틴의 제조방법이 개시되어 있다. 또한, 본 발명의 제조방법을 위해 유용한 비오틴 생산능력을 갖는스핀고모나스속 미생물이 개시되어 있다.

Description

비오틴의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. (a) 비오틴 생산능력을 갖는스핀고모나스속 미생물의 배양액을 배지에 제조하고, (b) 배지에 생산되고 축적된 비오틴을 수집하는 단 이루어진 비오틴의 제조방법.
  2. 제1항에 있어서, 비오틴 생산 능력을 갖는스핀고모나스속 미생물이스핀고모나스sp. SC-42405(FERM BP-3995) 또는 그의 변이주인 방법.
  3. 비오틴 생산 능력을 갖는스핀고모나스속의 비오틴 생산용 미생물.
  4. 제3항에 있어서, 미생물이스핀고모나스sp. SC-42405(FERM BP-3995) 또는 그의 변이주인 비오틴 생산용 미생물.
  5. 스핀고모나스sp. SC-42405(FERM BP-3995) 또는 그의 변이주.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930018253A 1992-09-10 1993-09-10 비오틴의제조방법 KR100297619B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP92-241748 1992-09-10
JP24174892 1992-09-10

Publications (2)

Publication Number Publication Date
KR940007188A true KR940007188A (ko) 1994-04-26
KR100297619B1 KR100297619B1 (ko) 2001-10-24

Family

ID=17078957

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930018253A KR100297619B1 (ko) 1992-09-10 1993-09-10 비오틴의제조방법

Country Status (11)

Country Link
US (1) US5432067A (ko)
EP (1) EP0589285B1 (ko)
JP (1) JP3428078B2 (ko)
KR (1) KR100297619B1 (ko)
CN (1) CN1050153C (ko)
AT (1) ATE174966T1 (ko)
DE (1) DE69322720T2 (ko)
DK (1) DK0589285T3 (ko)
ES (1) ES2126619T3 (ko)
HU (1) HU215083B (ko)
TW (1) TW255913B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102130241B1 (ko) 2019-01-09 2020-07-03 강명구 빙상용 썰매

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4329129B2 (ja) 1997-03-03 2009-09-09 住友化学株式会社 ビオチン生合成遺伝子を含むｄｎａ断片およびその利用
DE60013428T2 (de) * 1999-04-12 2005-09-15 Arkray, Inc. Alpha-glikolisierte aminosäure freisetzendes enzym
JP2010519927A (ja) 2007-03-08 2010-06-10 ビオトレンド−イノヴァサオ イ エンジェニャリア エン ビオテクノロジア， エスアー 構造的にカロテノイドを過剰生産する選抜された細菌の菌株又はその突然変異体の発酵による高純度カロテノイドの製造方法
CN102491908A (zh) * 2011-12-16 2012-06-13 华东理工大学 一种生物素生产废水中手性胺的回收方法
WO2021050371A1 (en) * 2019-09-09 2021-03-18 Albert Einstein College Of Medicine Biotin synthases for efficient production of biotin
KR20230070943A (ko) * 2021-11-15 2023-05-23 씨제이제일제당 (주) 바이오틴 신타제 활성을 갖는 폴리펩티드 변이체 및 이를 이용한 바이오틴 생산 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393129A (en) * 1964-12-23 1968-07-16 Takeda Chemical Industries Ltd Method for producing d-biotin
HU168313B (ko) * 1972-06-13 1976-03-28
JPS56160998A (en) * 1980-05-15 1981-12-11 Nippon Zeon Co Ltd Production of biotin active substance biotin vitamer
CA1322735C (en) * 1987-11-07 1993-10-05 Shinichiro Haze Microorganism having low acetate forming capability, and process for production of useful substrate using same
JP2722504B2 (ja) * 1988-07-14 1998-03-04 田辺製薬株式会社 新規微生物及びそれを用いるｄ−ビオチンの製法
CN1053217C (zh) * 1990-03-27 2000-06-07 资生堂株式会社 新的微生物以及利用这些微生物生产生物素同效维生素的方法
JP3006847B2 (ja) * 1990-03-27 2000-02-07 株式会社資生堂 新規微生物およびそれを用いるビオチン類の製造方法
DE4106375A1 (de) * 1991-02-28 1992-09-03 Degussa Eine l-carnitin-amidase produzierender mikroorganismus, l-carnitin-amidase, verfahren zu deren gewinnung und deren verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102130241B1 (ko) 2019-01-09 2020-07-03 강명구 빙상용 썰매

Also Published As

Publication number Publication date
EP0589285A2 (en) 1994-03-30
HU9302568D0 (en) 1993-11-29
HU215083B (hu) 1998-09-28
DE69322720D1 (de) 1999-02-04
HUT67685A (en) 1995-04-28
CN1050153C (zh) 2000-03-08
JPH06133790A (ja) 1994-05-17
DE69322720T2 (de) 1999-07-08
CN1084217A (zh) 1994-03-23
EP0589285B1 (en) 1998-12-23
TW255913B (ko) 1995-09-01
US5432067A (en) 1995-07-11
ATE174966T1 (de) 1999-01-15
EP0589285A3 (en) 1995-02-15
JP3428078B2 (ja) 2003-07-22
KR100297619B1 (ko) 2001-10-24
ES2126619T3 (es) 1999-04-01
DK0589285T3 (da) 1999-08-23

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