DE69232698T2 - Neuer megakaryocyten-verstärker - Google Patents

Neuer megakaryocyten-verstärker

Info

Publication number
DE69232698T2
DE69232698T2 DE69232698T DE69232698T DE69232698T2 DE 69232698 T2 DE69232698 T2 DE 69232698T2 DE 69232698 T DE69232698 T DE 69232698T DE 69232698 T DE69232698 T DE 69232698T DE 69232698 T2 DE69232698 T2 DE 69232698T2
Authority
DE
Germany
Prior art keywords
megakaryocyte
enhancer
meg
megakaryocyte enhancer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232698T
Other languages
German (de)
English (en)
Other versions
DE69232698D1 (de
Inventor
Kunihiro Hattori
Masayoshi Oh-Eda
Nozomi Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69232698D1 publication Critical patent/DE69232698D1/de
Publication of DE69232698T2 publication Critical patent/DE69232698T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Amplifiers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69232698T 1991-12-27 1992-12-24 Neuer megakaryocyten-verstärker Expired - Lifetime DE69232698T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP36152291 1991-12-27
JP12251892 1992-03-31
PCT/JP1992/001689 WO1993013132A1 (fr) 1991-12-27 1992-12-24 Nouvel amplificateur de megakaryocytes

Publications (2)

Publication Number Publication Date
DE69232698D1 DE69232698D1 (de) 2002-08-29
DE69232698T2 true DE69232698T2 (de) 2003-03-20

Family

ID=26459624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232698T Expired - Lifetime DE69232698T2 (de) 1991-12-27 1992-12-24 Neuer megakaryocyten-verstärker

Country Status (12)

Country Link
US (1) US5498698A (en:Method)
EP (1) EP0621285B1 (en:Method)
JP (1) JP3328341B2 (en:Method)
KR (1) KR100233701B1 (en:Method)
CN (1) CN1075148A (en:Method)
AT (1) ATE221084T1 (en:Method)
AU (1) AU658040B2 (en:Method)
CA (1) CA2126680C (en:Method)
DE (1) DE69232698T2 (en:Method)
ES (1) ES2180542T3 (en:Method)
TW (1) TW224975B (en:Method)
WO (1) WO1993013132A1 (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107366A (en) * 1992-10-23 2003-03-12 Chugai Pharmaceutical Co Ltd Genes coding for megakaryocyte potentiator
DE69503849T2 (de) * 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
US7375183B1 (en) * 1996-01-05 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof
JP2000505787A (ja) * 1996-01-05 2000-05-16 アメリカ合衆国 中皮抗原及びそれを標的化するための方法及びキット
US6809184B1 (en) * 1997-12-01 2004-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
US6589759B1 (en) 1999-03-30 2003-07-08 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
DE60039510D1 (de) 1999-05-27 2008-08-28 Us Gov Health & Human Serv Immunokonjugate mit hoher bindungsaffinität
US9200036B2 (en) 2002-07-12 2015-12-01 The Johns Hopkins University Mesothelin vaccines and model systems
AU2003259109A1 (en) * 2002-07-12 2004-02-02 The Johns Hopkins University Mesothelin vaccines and model systems
US20090110702A1 (en) * 2002-07-12 2009-04-30 The Johns Hopkins University Mesothelin Vaccines and Model Systems and Control of Tumors
US20040180387A1 (en) * 2003-03-13 2004-09-16 Fujirebio Diagnostics, Inc. Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer
SI2195017T1 (sl) 2007-10-01 2015-01-30 Bristol-Myers Squibb Company Človeška protitelesa, ki vežejo mezotelin in njihova uporaba

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU646530B2 (en) * 1990-12-28 1994-02-24 Asahi Kasei Kogyo Kabushiki Kaisha Novel megakaryocyte amplifier and production thereof
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法

Also Published As

Publication number Publication date
CA2126680C (en) 2002-10-08
JPH05331200A (ja) 1993-12-14
WO1993013132A1 (fr) 1993-07-08
EP0621285A4 (en) 1995-05-24
EP0621285B1 (en) 2002-07-24
ATE221084T1 (de) 2002-08-15
ES2180542T3 (es) 2003-02-16
KR100233701B1 (ko) 1999-12-01
AU658040B2 (en) 1995-03-30
CA2126680A1 (en) 1993-07-08
KR940703858A (ko) 1994-12-12
US5498698A (en) 1996-03-12
AU3172193A (en) 1993-07-28
EP0621285A1 (en) 1994-10-26
JP3328341B2 (ja) 2002-09-24
DE69232698D1 (de) 2002-08-29
CN1075148A (zh) 1993-08-11
TW224975B (en:Method) 1994-06-11

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