DE69232698T2 - Neuer megakaryocyten-verstärker - Google Patents

Neuer megakaryocyten-verstärker

Info

Publication number
DE69232698T2
DE69232698T2 DE69232698T DE69232698T DE69232698T2 DE 69232698 T2 DE69232698 T2 DE 69232698T2 DE 69232698 T DE69232698 T DE 69232698T DE 69232698 T DE69232698 T DE 69232698T DE 69232698 T2 DE69232698 T2 DE 69232698T2
Authority
DE
Germany
Prior art keywords
megakaryocyte
enhancer
meg
megakaryocyte enhancer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232698T
Other languages
German (de)
English (en)
Other versions
DE69232698D1 (de
Inventor
Kunihiro Hattori
Masayoshi Oh-Eda
Nozomi Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE69232698D1 publication Critical patent/DE69232698D1/de
Application granted granted Critical
Publication of DE69232698T2 publication Critical patent/DE69232698T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69232698T 1991-12-27 1992-12-24 Neuer megakaryocyten-verstärker Expired - Lifetime DE69232698T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP36152291 1991-12-27
JP12251892 1992-03-31
PCT/JP1992/001689 WO1993013132A1 (fr) 1991-12-27 1992-12-24 Nouvel amplificateur de megakaryocytes

Publications (2)

Publication Number Publication Date
DE69232698D1 DE69232698D1 (de) 2002-08-29
DE69232698T2 true DE69232698T2 (de) 2003-03-20

Family

ID=26459624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232698T Expired - Lifetime DE69232698T2 (de) 1991-12-27 1992-12-24 Neuer megakaryocyten-verstärker

Country Status (12)

Country Link
US (1) US5498698A (OSRAM)
EP (1) EP0621285B1 (OSRAM)
JP (1) JP3328341B2 (OSRAM)
KR (1) KR100233701B1 (OSRAM)
CN (1) CN1075148A (OSRAM)
AT (1) ATE221084T1 (OSRAM)
AU (1) AU658040B2 (OSRAM)
CA (1) CA2126680C (OSRAM)
DE (1) DE69232698T2 (OSRAM)
ES (1) ES2180542T3 (OSRAM)
TW (1) TW224975B (OSRAM)
WO (1) WO1993013132A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107366A (en) * 1992-10-23 2003-03-12 Chugai Pharmaceutical Co Ltd Genes coding for megakaryocyte potentiator
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
BR9506017A (pt) * 1994-03-31 1997-10-14 Amagen Inc Polipeptide poninculeotídeo isolado sequência de Dna e Cdna vetor de Dna célula hospedeira anticorpo composição farmacêutica derivado de Mgdf produto polípeptídeo Mgdf com grupos peg e preparação do mesmo e processo para produzir um polipeptídeo Mgdf humano e uma condição trombocitopênica para aumentar o número de megacarióticos maduroas e de plaquetas em um paciente necessitado dos mesmos e para fixar um polímero solúvel em água a um polipeptídeo Mgdf uma molècula de polietileno glicol a um polipeptideo Mgdf e poipeptideo glicol solúvel em água a um polipeptideo mgdf
US7375183B1 (en) 1996-01-05 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof
ATE254931T1 (de) * 1996-01-05 2003-12-15 Us Gov Health & Human Serv Mesothelinantigen, verfahren und testsatz zur targetierung
US6809184B1 (en) * 1997-12-01 2004-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
AU3877800A (en) 1999-03-30 2000-10-16 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
DE60039510D1 (de) 1999-05-27 2008-08-28 Us Gov Health & Human Serv Immunokonjugate mit hoher bindungsaffinität
US9200036B2 (en) 2002-07-12 2015-12-01 The Johns Hopkins University Mesothelin vaccines and model systems
US20090110702A1 (en) 2002-07-12 2009-04-30 The Johns Hopkins University Mesothelin Vaccines and Model Systems and Control of Tumors
EP1575500A4 (en) * 2002-07-12 2007-01-03 Univ Johns Hopkins MESOTHELIN VACCINE AND MODEL SYSTEMS
US20040180387A1 (en) * 2003-03-13 2004-09-16 Fujirebio Diagnostics, Inc. Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer
PL2195017T3 (pl) 2007-10-01 2015-03-31 Bristol Myers Squibb Co Ludzkie antyciała, które wiążą mezotelinę i ich zastosowania

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05247095A (ja) * 1990-12-28 1993-09-24 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製造方法および医薬組成物
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法

Also Published As

Publication number Publication date
AU658040B2 (en) 1995-03-30
WO1993013132A1 (fr) 1993-07-08
EP0621285A4 (en) 1995-05-24
CA2126680C (en) 2002-10-08
AU3172193A (en) 1993-07-28
US5498698A (en) 1996-03-12
JP3328341B2 (ja) 2002-09-24
CA2126680A1 (en) 1993-07-08
TW224975B (OSRAM) 1994-06-11
JPH05331200A (ja) 1993-12-14
EP0621285B1 (en) 2002-07-24
ES2180542T3 (es) 2003-02-16
KR940703858A (ko) 1994-12-12
EP0621285A1 (en) 1994-10-26
DE69232698D1 (de) 2002-08-29
CN1075148A (zh) 1993-08-11
ATE221084T1 (de) 2002-08-15
KR100233701B1 (ko) 1999-12-01

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