DE69207698T2 - Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthracencarbonsäure und deren therapeutische verwendung - Google Patents

Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthracencarbonsäure und deren therapeutische verwendung

Info

Publication number
DE69207698T2
DE69207698T2 DE69207698T DE69207698T DE69207698T2 DE 69207698 T2 DE69207698 T2 DE 69207698T2 DE 69207698 T DE69207698 T DE 69207698T DE 69207698 T DE69207698 T DE 69207698T DE 69207698 T2 DE69207698 T2 DE 69207698T2
Authority
DE
Germany
Prior art keywords
dioxo
dihydro
acid
arylalkylesters
anthracecarboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69207698T
Other languages
English (en)
Other versions
DE69207698D1 (de
Inventor
Sergio Rosini
Maurizio Mian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abiogen Pharma SRL
Original Assignee
Istituto Gentili SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Gentili SpA filed Critical Istituto Gentili SpA
Application granted granted Critical
Publication of DE69207698D1 publication Critical patent/DE69207698D1/de
Publication of DE69207698T2 publication Critical patent/DE69207698T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/95—Esters of quinone carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
DE69207698T 1991-05-03 1992-04-21 Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthracencarbonsäure und deren therapeutische verwendung Expired - Fee Related DE69207698T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI911215A IT1247884B (it) 1991-05-03 1991-05-03 Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica
PCT/EP1992/000881 WO1992019584A1 (en) 1991-05-03 1992-04-21 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity

Publications (2)

Publication Number Publication Date
DE69207698D1 DE69207698D1 (de) 1996-02-29
DE69207698T2 true DE69207698T2 (de) 1996-07-18

Family

ID=11359835

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69207698T Expired - Fee Related DE69207698T2 (de) 1991-05-03 1992-04-21 Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthracencarbonsäure und deren therapeutische verwendung

Country Status (21)

Country Link
US (1) US5330981A (de)
EP (1) EP0537313B1 (de)
JP (1) JPH0692348B2 (de)
KR (1) KR100226082B1 (de)
AT (1) ATE133157T1 (de)
AU (1) AU648894B2 (de)
BR (1) BR9205255A (de)
CZ (1) CZ280027B6 (de)
DE (1) DE69207698T2 (de)
DK (1) DK0537313T3 (de)
ES (1) ES2082468T3 (de)
FI (1) FI104166B1 (de)
GR (1) GR3019417T3 (de)
HU (1) HUT63605A (de)
IT (1) IT1247884B (de)
MX (1) MX9202015A (de)
NO (1) NO179245C (de)
PT (1) PT100439B (de)
RU (1) RU2087462C1 (de)
SK (1) SK280738B6 (de)
WO (1) WO1992019584A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9417102D0 (en) * 1994-08-24 1994-10-12 Lilly Industries Ltd Pharmaceutical compounds
TWI249519B (en) 2000-08-29 2006-02-21 Nobex Corp Immunoregulatory compounds and derivatives and methods of treating diseases therewith
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
US7932366B2 (en) 2004-07-07 2011-04-26 Biocon Limited Synthesis of azo bonded immunoregulatory compounds
CN101475484B (zh) * 2009-01-05 2012-07-18 东南大学 骨靶向抗炎药物合成方法及其应用
CN103709052B (zh) * 2014-01-12 2016-01-27 何黎琴 一种大黄酸胺基醇酯类化合物、其制备方法及医药用途
CN104945269A (zh) * 2015-06-23 2015-09-30 常州善美药物研究开发中心有限公司 一种大黄酸羧酸酯类衍生物及其应用
CN109053798B (zh) * 2018-07-23 2020-11-17 遵义医科大学 一种大黄酸酯衍生物及其制备方法与应用
CN115521320B (zh) * 2021-06-25 2023-09-05 沈阳兴齐眼药股份有限公司 一种制备普拉洛芬的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis

Also Published As

Publication number Publication date
AU1670092A (en) 1992-12-21
NO925048L (no) 1992-12-30
ES2082468T3 (es) 1996-03-16
NO179245B (no) 1996-05-28
FI925944A (fi) 1992-12-30
PT100439A (pt) 1993-08-31
KR100226082B1 (en) 1999-10-15
HUT63605A (en) 1993-09-28
IT1247884B (it) 1995-01-05
JPH0692348B2 (ja) 1994-11-16
DE69207698D1 (de) 1996-02-29
JPH05507733A (ja) 1993-11-04
BR9205255A (pt) 1993-08-31
FI925944A0 (fi) 1992-12-30
ITMI911215A0 (it) 1991-05-03
DK0537313T3 (da) 1996-06-03
FI104166B (fi) 1999-11-30
MX9202015A (es) 1992-11-01
RU2087462C1 (ru) 1997-08-20
NO925048D0 (no) 1992-12-30
FI104166B1 (fi) 1999-11-30
GR3019417T3 (en) 1996-06-30
PT100439B (pt) 1999-10-29
HU9204171D0 (en) 1993-04-28
SK386492A3 (en) 1995-04-12
SK280738B6 (sk) 2000-07-11
EP0537313B1 (de) 1996-01-17
ITMI911215A1 (it) 1992-11-03
ATE133157T1 (de) 1996-02-15
CZ386492A3 (en) 1993-06-16
AU648894B2 (en) 1994-05-05
US5330981A (en) 1994-07-19
EP0537313A1 (de) 1993-04-21
WO1992019584A1 (en) 1992-11-12
CZ280027B6 (cs) 1995-09-13
NO179245C (no) 1996-09-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ABIOGEN PHARMA S.R.L., ROM/ROMA, IT

8339 Ceased/non-payment of the annual fee