DE69108408T2 - 4,5-dihydroxy und 4,5,8-trihydroxy-9,10-dioxo-2-anthracencarbonsäure-dikohlensäureester und urethane mit therapeutischer wirkung. - Google Patents

4,5-dihydroxy und 4,5,8-trihydroxy-9,10-dioxo-2-anthracencarbonsäure-dikohlensäureester und urethane mit therapeutischer wirkung.

Info

Publication number
DE69108408T2
DE69108408T2 DE69108408T DE69108408T DE69108408T2 DE 69108408 T2 DE69108408 T2 DE 69108408T2 DE 69108408 T DE69108408 T DE 69108408T DE 69108408 T DE69108408 T DE 69108408T DE 69108408 T2 DE69108408 T2 DE 69108408T2
Authority
DE
Germany
Prior art keywords
acid
trihydroxy
urethanes
dioxo
dihydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69108408T
Other languages
English (en)
Other versions
DE69108408D1 (de
Inventor
Sergio Rosini
Maurizio Mian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Gentili SpA
Original Assignee
Istituto Gentili SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Gentili SpA filed Critical Istituto Gentili SpA
Application granted granted Critical
Publication of DE69108408D1 publication Critical patent/DE69108408D1/de
Publication of DE69108408T2 publication Critical patent/DE69108408T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69108408T 1990-12-11 1991-12-03 4,5-dihydroxy und 4,5,8-trihydroxy-9,10-dioxo-2-anthracencarbonsäure-dikohlensäureester und urethane mit therapeutischer wirkung. Expired - Fee Related DE69108408T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT02234390A IT1244886B (it) 1990-12-11 1990-12-11 Dicarbonati e uretani dell'acido 4,5-diidrossi- e 4,5,8-triidrossi- 9,10-diidro-9,10-diosso-2-antracencarbossilico ad azione terapeutica
PCT/EP1991/002290 WO1992010464A1 (en) 1990-12-11 1991-12-03 4,5-dihydroxy- and 4,5,8-trihydroxy- 9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid dicarbonates and urethans having therapeutical activities

Publications (2)

Publication Number Publication Date
DE69108408D1 DE69108408D1 (de) 1995-04-27
DE69108408T2 true DE69108408T2 (de) 1995-07-27

Family

ID=11194956

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69108408T Expired - Fee Related DE69108408T2 (de) 1990-12-11 1991-12-03 4,5-dihydroxy und 4,5,8-trihydroxy-9,10-dioxo-2-anthracencarbonsäure-dikohlensäureester und urethane mit therapeutischer wirkung.

Country Status (13)

Country Link
US (1) US5362750A (de)
EP (1) EP0561846B1 (de)
JP (1) JPH06503078A (de)
AT (1) ATE120180T1 (de)
AU (1) AU657290B2 (de)
CA (1) CA2098112A1 (de)
DE (1) DE69108408T2 (de)
DK (1) DK0561846T3 (de)
ES (1) ES2069915T3 (de)
IT (1) IT1244886B (de)
MX (1) MX9102518A (de)
PT (1) PT99737A (de)
WO (1) WO1992010464A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2090743A1 (en) * 1992-02-28 1993-08-29 Michael Brunavs Pharmaceutical compounds
GB9316912D0 (en) * 1993-08-13 1993-09-29 Lilly Industries Ltd Pharmaceutical compounds
GB9316923D0 (en) * 1993-08-13 1993-09-29 Lilly Industries Ltd Pharmaceutical compounds
GB9417102D0 (en) * 1994-08-24 1994-10-12 Lilly Industries Ltd Pharmaceutical compounds
US6953788B1 (en) 1996-09-19 2005-10-11 Aventis Pharmaceuticals Inc. 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
US6610750B1 (en) * 2000-09-15 2003-08-26 Laboratoires Negma Treatment of osteoarthritis
US20050055024A1 (en) 2003-09-08 2005-03-10 James Anthony H. Orthopaedic implant and screw assembly
KR100715076B1 (ko) 2005-06-10 2007-05-04 대화제약 주식회사 디아세레인의 새로운 제조방법
CN1748675A (zh) * 2005-07-11 2006-03-22 丛晓东 大黄酸类化合物的复合物及制备方法与治疗糖尿病的应用
US9766269B2 (en) 2012-12-29 2017-09-19 Power Probe TEK, LLC Conductive test probe
JP6376340B2 (ja) * 2014-06-26 2018-08-22 川崎化成工業株式会社 光ラジカル重合開始剤
CN109627169A (zh) * 2017-12-05 2019-04-16 何黎琴 No供体型大黄酸衍生物、其制备方法及医药用途
CN109053798B (zh) * 2018-07-23 2020-11-17 遵义医科大学 一种大黄酸酯衍生物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis
IT1189097B (it) * 1986-05-02 1988-01-28 Proter Spa Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi
JPH027302A (ja) * 1988-06-27 1990-01-11 Sumitomo Electric Ind Ltd 有機導電性錯体

Also Published As

Publication number Publication date
AU657290B2 (en) 1995-03-09
ATE120180T1 (de) 1995-04-15
IT1244886B (it) 1994-09-13
DK0561846T3 (da) 1995-08-21
US5362750A (en) 1994-11-08
JPH06503078A (ja) 1994-04-07
MX9102518A (es) 1992-06-01
CA2098112A1 (en) 1992-06-12
PT99737A (pt) 1992-11-30
EP0561846A1 (de) 1993-09-29
ES2069915T3 (es) 1995-05-16
IT9022343A0 (it) 1990-12-11
WO1992010464A1 (en) 1992-06-25
DE69108408D1 (de) 1995-04-27
EP0561846B1 (de) 1995-03-22
IT9022343A1 (it) 1992-06-11
AU9015791A (en) 1992-07-08

Similar Documents

Publication Publication Date Title
GR3017282T3 (en) Novel arylpyridazines, their manufacture, use and medicaments containing them.
DE69401204D1 (de) Gonadotropin enthaltende gefriergetrocknete troepfen
BR9404842A (pt) Compostos,processo para sua preparação e formulação farmacêutica
DE69326776T2 (de) Verwendung von n-arylmethylen ethylendiamintriacetate, n-arylmethylen iminodiacetat oder n,n'-diarylmethylen ethylendiamindiacetat gegen oxidativen stress
NO306403B1 (no) Nye sulfonamidopyrimidiner, anvendelse av dem og farmasöytiske preparater inneholdende dem
FI960102A0 (fi) Uusi farmaseuttinen seos
DE59508891D1 (de) Hautpflegemittel
CO4290417A1 (es) Nuevas benzoilguanidinas como medicamentos y su preparacion .
DK0589893T3 (da) Anvendelse af et bakteriocin som antimikrobielt middel til fremstilling af et lægemiddel til behandl ing af maveforstyrrelser forbundet med helicobacter pylori
DE69108408T2 (de) 4,5-dihydroxy und 4,5,8-trihydroxy-9,10-dioxo-2-anthracencarbonsäure-dikohlensäureester und urethane mit therapeutischer wirkung.
ATE112239T1 (de) Vaterit und verfahren zu dessen herstellung.
AU3078892A (en) Human interleukin-8 analogs
MX24839A (es) 3-arilcarbonil-1-aminoalquilo-1h-indoles, proceso para su preparacion y composicion farmaceutica quelos contiene.
ATE107853T1 (de) Orales, melatonin enthaltendes arzneimittel.
ES2062137T3 (es) Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea.
ES2070109T3 (es) Sales diaminicas de acido clavulanico.
DK0443848T3 (da) Nyt antiulcermiddel
DE69431662T2 (de) Stabilisierte tablettenformulierung
DE69323191D1 (de) Wasserlösliche retinoide
MX9300136A (es) Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen.
DE69215085T2 (de) Aminoacylderivate von gem-diphosphonsauren,verfahren zu deren herstellung und pharmazeutische zubereitungen,die sie enthalten
ATE196465T1 (de) Analoge von difluoro-staton
MX9203096A (es) Derivados de n-(2'-aminofenil)-benzamida, proceso para la preparacion de la misma y composiciones farmaceuticas que los contienen.
SE9002274D0 (sv) Novel 3,3'-dithiobis(propionic esters).
TH7956S (th) สร้อยคอ

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee