ITMI911215A1 - Esteri arilalchilici dell'acido 4, 5 diidrossi-9, 10-diidro-9, 10-diosso 2-antracencarbossilico ad azione terapeutica - Google Patents

Esteri arilalchilici dell'acido 4, 5 diidrossi-9, 10-diidro-9, 10-diosso 2-antracencarbossilico ad azione terapeutica

Info

Publication number
ITMI911215A1
ITMI911215A1 IT001215A ITMI911215A ITMI911215A1 IT MI911215 A1 ITMI911215 A1 IT MI911215A1 IT 001215 A IT001215 A IT 001215A IT MI911215 A ITMI911215 A IT MI911215A IT MI911215 A1 ITMI911215 A1 IT MI911215A1
Authority
IT
Italy
Prior art keywords
dihydro
esters
acid
anthracencarboxyl
aryalkyl
Prior art date
Application number
IT001215A
Other languages
English (en)
Inventor
Maurizio Mian
Sergio Rosini
Original Assignee
Gentili Ist Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentili Ist Spa filed Critical Gentili Ist Spa
Publication of ITMI911215A0 publication Critical patent/ITMI911215A0/it
Priority to ITMI911215A priority Critical patent/IT1247884B/it
Priority to AU16700/92A priority patent/AU648894B2/en
Priority to RU9292016533A priority patent/RU2087462C1/ru
Priority to DK92909059.5T priority patent/DK0537313T3/da
Priority to AT92909059T priority patent/ATE133157T1/de
Priority to CS923864A priority patent/CZ280027B6/cs
Priority to US07/966,038 priority patent/US5330981A/en
Priority to DE69207698T priority patent/DE69207698T2/de
Priority to BR9205255A priority patent/BR9205255A/pt
Priority to PCT/EP1992/000881 priority patent/WO1992019584A1/en
Priority to ES92909059T priority patent/ES2082468T3/es
Priority to HU929204171A priority patent/HUT63605A/hu
Priority to SK3864-92A priority patent/SK280738B6/sk
Priority to JP4508484A priority patent/JPH0692348B2/ja
Priority to EP92909059A priority patent/EP0537313B1/en
Priority to MX9202015A priority patent/MX9202015A/es
Priority to PT100439A priority patent/PT100439B/pt
Publication of ITMI911215A1 publication Critical patent/ITMI911215A1/it
Priority to FI925944A priority patent/FI104166B1/fi
Priority to KR1019920703409A priority patent/KR100226082B1/ko
Priority to NO925048A priority patent/NO179245C/no
Application granted granted Critical
Publication of IT1247884B publication Critical patent/IT1247884B/it
Priority to GR960400797T priority patent/GR3019417T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/95—Esters of quinone carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ITMI911215A 1991-05-03 1991-05-03 Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica IT1247884B (it)

Priority Applications (21)

Application Number Priority Date Filing Date Title
ITMI911215A IT1247884B (it) 1991-05-03 1991-05-03 Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica
ES92909059T ES2082468T3 (es) 1991-05-03 1992-04-21 Arilalquil esteres del acido 4,5-dihidroxi-9,10-dihidro-9,10-dioxo-2-antracenocarboxilico con actividad terapeutica.
SK3864-92A SK280738B6 (sk) 1991-05-03 1992-04-21 Arylalkylestery 4,5-dihydroxy-9,10-dihydro-9,10-di
DK92909059.5T DK0537313T3 (da) 1991-05-03 1992-04-21 Arylalkylestere af 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracencarboxylsyre med terapeutisk aktivitet
AT92909059T ATE133157T1 (de) 1991-05-03 1992-04-21 Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthrace carbonsäure und deren therapeutische verwendung
CS923864A CZ280027B6 (cs) 1991-05-03 1992-04-21 Arylalkylestery 4,5-dihydroxy-9,10-dihyhro-9,10-dioxo-2-anthracenkarboxylových kyselin, způsob výroby a farmaceutické prostředky s jejich obsahem
US07/966,038 US5330981A (en) 1991-05-03 1992-04-21 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity
DE69207698T DE69207698T2 (de) 1991-05-03 1992-04-21 Arylalkylester der 4,5-dihydoxy-9,10-dihydro-9,10-dioxo-2-anthracencarbonsäure und deren therapeutische verwendung
BR9205255A BR9205255A (pt) 1991-05-03 1992-04-21 Aril aquil esteres de acido 4,5-dihidroxi-9,10-dihidro-9,10-dioxo-2-antraceno carboxilico com atividade terapeutica
PCT/EP1992/000881 WO1992019584A1 (en) 1991-05-03 1992-04-21 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity
AU16700/92A AU648894B2 (en) 1991-05-03 1992-04-21 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity
HU929204171A HUT63605A (en) 1991-05-03 1992-04-21 Process for producing aralkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid, as well as pharmaceutical compositions comprising same
RU9292016533A RU2087462C1 (ru) 1991-05-03 1992-04-21 Арилалкильные эфиры 4,5-дигидрокси-9,10-дигидро-9, 10-диоксо-2-антраценкарбоновой кислоты, обладающие противовоспалительной активностью. способ их получения и фармацевтическая композиция, обладающая противовоспалительной активностью
JP4508484A JPH0692348B2 (ja) 1991-05-03 1992-04-21 治療活性を有する４，５―ジヒドロキシ―９，１０―ジヒドロ―９，１０―ジオキソ―２―アントラセンカルボン酸のアリールアルキルエステル
EP92909059A EP0537313B1 (en) 1991-05-03 1992-04-21 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity
MX9202015A MX9202015A (es) 1991-05-03 1992-04-30 Esteres aril alquilicos de acido 4,5-di hidroxi -9,10- di hidro-9,10-di oxo --2- antracen carboxilico que tienen actividad terapeutica.
PT100439A PT100439B (pt) 1991-05-03 1992-04-30 Esteres de arilalquilo do acido 4,5-dihidroxi-9,10-dihidro-9,10-dioxo-2-antracenocarboxilico com actividade terapeutica
FI925944A FI104166B1 (fi) 1991-05-03 1992-12-30 Menetelmä lääkeianeina käyttökelpoisten 4,5-dihydroksi-9,10-dihydro-9,10-diokso-2-antraseenikarboksyylihapon aryylialkyyliesterien valmistamiseksi
KR1019920703409A KR100226082B1 (en) 1991-05-03 1992-12-30 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity
NO925048A NO179245C (no) 1991-05-03 1992-12-30 Arylalkylestere av 4,5-dihydroksy-9,10-dihydro-9,10-diokso-2-antracenkarboksylsyre med terapeutisk aktivitet
GR960400797T GR3019417T3 (en) 1991-05-03 1996-03-26 Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911215A IT1247884B (it) 1991-05-03 1991-05-03 Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica

Publications (3)

Publication Number Publication Date
ITMI911215A0 ITMI911215A0 (it) 1991-05-03
ITMI911215A1 true ITMI911215A1 (it) 1992-11-03
IT1247884B IT1247884B (it) 1995-01-05

Family

ID=11359835

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911215A IT1247884B (it) 1991-05-03 1991-05-03 Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica

Country Status (21)

Country Link
US (1) US5330981A (it)
EP (1) EP0537313B1 (it)
JP (1) JPH0692348B2 (it)
KR (1) KR100226082B1 (it)
AT (1) ATE133157T1 (it)
AU (1) AU648894B2 (it)
BR (1) BR9205255A (it)
CZ (1) CZ280027B6 (it)
DE (1) DE69207698T2 (it)
DK (1) DK0537313T3 (it)
ES (1) ES2082468T3 (it)
FI (1) FI104166B1 (it)
GR (1) GR3019417T3 (it)
HU (1) HUT63605A (it)
IT (1) IT1247884B (it)
MX (1) MX9202015A (it)
NO (1) NO179245C (it)
PT (1) PT100439B (it)
RU (1) RU2087462C1 (it)
SK (1) SK280738B6 (it)
WO (1) WO1992019584A1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9417102D0 (en) * 1994-08-24 1994-10-12 Lilly Industries Ltd Pharmaceutical compounds
TWI249519B (en) * 2000-08-29 2006-02-21 Nobex Corp Immunoregulatory compounds and derivatives and methods of treating diseases therewith
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
EP1773767B1 (en) 2004-07-07 2016-03-09 Biocon Limited Synthesis of azo bonded immunoregulatory compounds
CN101475484B (zh) * 2009-01-05 2012-07-18 东南大学 骨靶向抗炎药物合成方法及其应用
CN103709052B (zh) * 2014-01-12 2016-01-27 何黎琴 一种大黄酸胺基醇酯类化合物、其制备方法及医药用途
CN104945269A (zh) * 2015-06-23 2015-09-30 常州善美药物研究开发中心有限公司 一种大黄酸羧酸酯类衍生物及其应用
CN109053798B (zh) * 2018-07-23 2020-11-17 遵义医科大学 一种大黄酸酯衍生物及其制备方法与应用
CN115521320B (zh) * 2021-06-25 2023-09-05 沈阳兴齐眼药股份有限公司 一种制备普拉洛芬的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis

Also Published As

Publication number Publication date
PT100439A (pt) 1993-08-31
FI925944A (fi) 1992-12-30
NO925048D0 (no) 1992-12-30
FI925944A0 (fi) 1992-12-30
AU648894B2 (en) 1994-05-05
CZ386492A3 (en) 1993-06-16
MX9202015A (es) 1992-11-01
JPH05507733A (ja) 1993-11-04
IT1247884B (it) 1995-01-05
NO179245C (no) 1996-09-04
ES2082468T3 (es) 1996-03-16
HU9204171D0 (en) 1993-04-28
NO925048L (no) 1992-12-30
NO179245B (no) 1996-05-28
WO1992019584A1 (en) 1992-11-12
RU2087462C1 (ru) 1997-08-20
ATE133157T1 (de) 1996-02-15
DK0537313T3 (da) 1996-06-03
PT100439B (pt) 1999-10-29
DE69207698D1 (de) 1996-02-29
US5330981A (en) 1994-07-19
KR100226082B1 (en) 1999-10-15
ITMI911215A0 (it) 1991-05-03
EP0537313A1 (en) 1993-04-21
CZ280027B6 (cs) 1995-09-13
AU1670092A (en) 1992-12-21
GR3019417T3 (en) 1996-06-30
BR9205255A (pt) 1993-08-31
EP0537313B1 (en) 1996-01-17
SK280738B6 (sk) 2000-07-11
DE69207698T2 (de) 1996-07-18
SK386492A3 (en) 1995-04-12
FI104166B (fi) 1999-11-30
JPH0692348B2 (ja) 1994-11-16
HUT63605A (en) 1993-09-28
FI104166B1 (fi) 1999-11-30

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529