DE69205566D1 - Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt. - Google Patents

Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt.

Info

Publication number
DE69205566D1
DE69205566D1 DE69205566T DE69205566T DE69205566D1 DE 69205566 D1 DE69205566 D1 DE 69205566D1 DE 69205566 T DE69205566 T DE 69205566T DE 69205566 T DE69205566 T DE 69205566T DE 69205566 D1 DE69205566 D1 DE 69205566D1
Authority
DE
Germany
Prior art keywords
enthaelt
impfstoff
hsv
simplex
herpes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69205566T
Other languages
English (en)
Other versions
DE69205566T2 (de
DE69205566T3 (de
Inventor
Myriam Francotte
Jean-Paul Prieels
Moncef Slaoui
Nathalie Garcon-Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
GlaxoSmithKline Biologicals SA
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10691946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69205566(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by GlaxoSmithKline Biologicals SA, SmithKline Beecham Biologicals SA filed Critical GlaxoSmithKline Biologicals SA
Application granted granted Critical
Publication of DE69205566D1 publication Critical patent/DE69205566D1/de
Publication of DE69205566T2 publication Critical patent/DE69205566T2/de
Publication of DE69205566T3 publication Critical patent/DE69205566T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE1992605566 1991-03-21 1992-03-17 Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt. Expired - Lifetime DE69205566T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9105992A GB9105992D0 (en) 1991-03-21 1991-03-21 Vaccine
PCT/EP1992/000592 WO1992016231A1 (en) 1991-03-21 1992-03-17 HERPES SIMPLEX VACCINE COMPRISING HSV GLYCOPROTEIN gD AND 3 dEACYLATED MONOPHOSPHORYL LIPID A

Publications (3)

Publication Number Publication Date
DE69205566D1 true DE69205566D1 (en) 1995-11-23
DE69205566T2 DE69205566T2 (de) 1996-04-18
DE69205566T3 DE69205566T3 (de) 2002-09-05

Family

ID=10691946

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1992605566 Expired - Lifetime DE69205566T3 (de) 1991-03-21 1992-03-17 Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt.

Country Status (34)

Country Link
US (1) US6027730A (de)
EP (1) EP0576478B2 (de)
JP (1) JP3530526B2 (de)
KR (1) KR100224329B1 (de)
CN (2) CN1058191C (de)
AP (1) AP298A (de)
AT (1) ATE129160T1 (de)
AU (1) AU650521B2 (de)
BR (1) BR9205745A (de)
CA (1) CA2106492C (de)
CY (1) CY1936A (de)
CZ (1) CZ280505B6 (de)
DE (1) DE69205566T3 (de)
DK (1) DK0576478T4 (de)
ES (1) ES2081102T5 (de)
FI (1) FI107881B (de)
GB (1) GB9105992D0 (de)
GR (1) GR3017884T3 (de)
HK (1) HK1004525A1 (de)
HU (1) HU218025B (de)
IE (1) IE69560B1 (de)
IL (1) IL101290A (de)
MA (1) MA22471A1 (de)
MX (1) MX9201245A (de)
MY (1) MY110086A (de)
NO (1) NO307499B1 (de)
NZ (1) NZ242057A (de)
PL (1) PL170059B1 (de)
PT (1) PT100262B (de)
SA (1) SA92120459B1 (de)
SK (1) SK279190B6 (de)
WO (1) WO1992016231A1 (de)
YU (1) YU28392A (de)
ZA (1) ZA922011B (de)

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US9273326B2 (en) 2004-04-30 2016-03-01 The Brigham And Women's Hospital, Inc. Tetracycline-regulated gene expression in HSV-1 vectors
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KR100278157B1 (ko) * 1992-06-25 2001-01-15 장 스테판느 보조약을 함유하는 백신 조성물
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DK0812593T4 (da) * 1993-03-23 2008-05-13 Smithkline Beecham Biolog Vaccinepræparater indeholdende 3-O-deacyleret monophosphoryllipid-A
CA2163550A1 (en) * 1993-05-25 1994-12-08 Gerald E. Hancock Adjuvants for vaccines against respiratory syncytial virus

Also Published As

Publication number Publication date
IE69560B1 (en) 1996-10-02
JPH06505727A (ja) 1994-06-30
AP298A (en) 1994-01-14
AU1365792A (en) 1992-10-21
CA2106492C (en) 2003-12-09
EP0576478A1 (de) 1994-01-05
CZ280505B6 (cs) 1996-02-14
GB9105992D0 (en) 1991-05-08
MA22471A1 (fr) 1992-10-01
CN1058191C (zh) 2000-11-08
NO307499B1 (no) 2000-04-17
WO1992016231A1 (en) 1992-10-01
SK94693A3 (en) 1994-05-11
MX9201245A (es) 1992-10-01
US6027730A (en) 2000-02-22
FI934134A0 (fi) 1993-09-21
DK0576478T3 (da) 1995-12-04
AP9200368A0 (en) 1992-04-30
EP0576478B2 (de) 2001-04-18
HUT67052A (en) 1995-01-30
HK1004525A1 (en) 1998-11-27
MY110086A (en) 1997-12-31
IE920881A1 (en) 1992-09-23
ATE129160T1 (de) 1995-11-15
CN1065997A (zh) 1992-11-11
PT100262B (pt) 2001-05-31
CA2106492A1 (en) 1992-09-22
GR3017884T3 (en) 1996-01-31
DE69205566T2 (de) 1996-04-18
FI107881B (fi) 2001-10-31
ZA922011B (en) 1993-01-27
DE69205566T3 (de) 2002-09-05
IL101290A0 (en) 1992-11-15
EP0576478B1 (de) 1995-10-18
SK279190B6 (sk) 1998-07-08
KR100224329B1 (ko) 1999-10-15
JP3530526B2 (ja) 2004-05-24
ES2081102T3 (es) 1996-02-16
SA92120459B1 (ar) 2005-06-14
ES2081102T5 (es) 2001-09-01
NZ242057A (en) 1993-12-23
HU218025B (hu) 2000-05-28
CZ195893A3 (en) 1994-07-13
IL101290A (en) 1996-07-23
CY1936A (en) 1992-03-17
YU28392A (sh) 1994-11-15
PT100262A (pt) 1993-06-30
NO933343D0 (no) 1993-09-20
NO933343L (no) 1993-09-20
PL170059B1 (pl) 1996-10-31
BR9205745A (pt) 1994-10-18
CN1201692A (zh) 1998-12-16
CN1101226C (zh) 2003-02-12
AU650521B2 (en) 1994-06-23
FI934134A (fi) 1993-09-21
DK0576478T4 (da) 2001-07-23
HU9302645D0 (en) 1994-01-28

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