DE69203488T2 - Niedrigdosierte getrocknete pharmazeutische Präparate. - Google Patents

Niedrigdosierte getrocknete pharmazeutische Präparate.

Info

Publication number
DE69203488T2
DE69203488T2 DE69203488T DE69203488T DE69203488T2 DE 69203488 T2 DE69203488 T2 DE 69203488T2 DE 69203488 T DE69203488 T DE 69203488T DE 69203488 T DE69203488 T DE 69203488T DE 69203488 T2 DE69203488 T2 DE 69203488T2
Authority
DE
Germany
Prior art keywords
disclosed
weight
agent
pharmaceutical preparations
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69203488T
Other languages
English (en)
Other versions
DE69203488D1 (de
DE69203488T3 (de
Inventor
Haan Pieter De
Marcus Johannes Deurloo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8207548&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69203488(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69203488D1 publication Critical patent/DE69203488D1/de
Application granted granted Critical
Publication of DE69203488T2 publication Critical patent/DE69203488T2/de
Publication of DE69203488T3 publication Critical patent/DE69203488T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
DE69203488T 1991-03-12 1992-03-09 Niedrigdosierte getrocknete pharmazeutische Präparate. Expired - Lifetime DE69203488T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91200524 1991-03-12
EP91200524 1991-03-12

Publications (3)

Publication Number Publication Date
DE69203488D1 DE69203488D1 (de) 1995-08-24
DE69203488T2 true DE69203488T2 (de) 1996-01-11
DE69203488T3 DE69203488T3 (de) 2006-07-06

Family

ID=8207548

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69203488T Expired - Lifetime DE69203488T3 (de) 1991-03-12 1992-03-09 Niedrigdosierte getrocknete pharmazeutische Präparate.

Country Status (18)

Country Link
US (1) US5382434A (de)
EP (1) EP0503521B2 (de)
JP (1) JP3474210B2 (de)
KR (1) KR100198017B1 (de)
CN (1) CN1039086C (de)
AT (1) ATE125155T1 (de)
AU (1) AU651869B2 (de)
CA (1) CA2062428C (de)
DE (1) DE69203488T3 (de)
DK (1) DK0503521T4 (de)
ES (1) ES2077897T5 (de)
FI (1) FI100770B (de)
GR (1) GR3017737T3 (de)
HK (1) HK1002018A1 (de)
IE (1) IE67345B1 (de)
NO (1) NO305055B1 (de)
NZ (1) NZ241915A (de)
ZA (1) ZA921659B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA924617B (en) 1991-03-25 1994-05-27 Boart International S A Pty Lt A percussion drill bit
ZA939566B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for dry blend compression od medicaments.
ZA939565B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.
US5928668A (en) * 1993-12-21 1999-07-27 Applied Analytical Industries, Inc. Method for dry blend compression of medicaments
US5976570A (en) * 1993-12-21 1999-11-02 Applied Analytical Industries, Inc. Method for preparing low dose pharmaceutical products
ZA949929B (en) * 1993-12-23 1995-08-23 Akzo Nobel Nv Sugar-coated pharmaceutical dosage unit.
US6077533A (en) * 1994-05-25 2000-06-20 Purdue Pharma L.P. Powder-layered oral dosage forms
CZ289081B6 (cs) * 1994-09-22 2001-10-17 Akzo Nobel N. V. Způsob výroby farmaceutické lékové formy a tableta
CA2159419C (en) * 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water
EP0820237A4 (de) * 1995-01-25 1999-01-20 Wrigley W M Jun Co Verbesserte einstaubmischung und verfahren zur herstellung von kaugummi mit ihrer hilfe
CN1119998C (zh) * 1995-06-22 2003-09-03 阿克佐诺贝尔公司 去氧孕烯的压制干颗粒片
DE19652196A1 (de) 1996-12-16 1998-06-18 Jenapharm Gmbh Homogene steroidhaltige Präformulierungen zur Herstellung niedrigdosierter fester und halbfester pharmazeutischer Zubereitungen
WO2000050041A1 (en) * 1999-02-24 2000-08-31 Akzo Nobel N.V. Pharmaceutical compositions containing a crystalline form of the progestagen-(17alpha)-17-hydroxy-11-methylene-19-nor-pregna-4,15-dien-20-yn-3-one (org 30659) and lactose
KR20010006835A (ko) * 1999-03-25 2001-01-26 김선진 경구용 속붕해정
DE19917347A1 (de) * 1999-04-16 2000-11-09 Gsf Forschungszentrum Umwelt Verfahren und Vorrichtung zum trockenen Anbringen von Substanzen an inhalierbare pulverförmige Trägerstoffe
ITMI991582A1 (it) * 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
US6787531B1 (en) * 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
FR2801218B1 (fr) * 1999-11-23 2001-12-28 Hoechst Marion Roussel Inc Compositions pharmaceutiques comprenant de la trimegestone, leurs procedes de preparation ainsi que le conditionnement primaire les renfermant
WO2001045674A1 (en) * 1999-12-20 2001-06-28 Cocensys, Inc. Process for producing nanometer particles by fluid bed spray-drying
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
DE60130657T2 (de) 2000-07-20 2008-07-03 Campina Nederland Holding B.V. Methode zur herstellung eines kristallinen tablettierungshilfstoffes, der so erhaltene hilfsstoff und seine verwendung
DK1361881T3 (da) * 2000-12-14 2006-02-20 Ortho Mcneil Pharm Inc Steroide hormonprodukter og fremgangsmåder til fremstilling heraf
JPWO2002069934A1 (ja) * 2001-03-06 2004-07-02 協和醗酵工業株式会社 口腔内速崩壊性製剤
KR20030081489A (ko) * 2001-03-06 2003-10-17 교와 핫꼬 고교 가부시끼가이샤 당알콜을 함유하는 분무건조 분말의 용도
CZ20032959A3 (cs) * 2001-05-01 2004-01-14 Pfizer Products Inc. Způsob přípravy farmaceutické kompozice s nízkou dávkou léčiva mající rovnoměrnou distribuci a účinnost léčiva
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
US6962908B2 (en) 2001-12-21 2005-11-08 Warner Chilcott Company Inc. Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
AU2004233997C1 (en) 2003-04-29 2014-01-30 Massachusetts Institiute Of Technology Methods and devices for the sustained release of multiple drugs
US7444197B2 (en) 2004-05-06 2008-10-28 Smp Logic Systems Llc Methods, systems, and software program for validation and monitoring of pharmaceutical manufacturing processes
US7799273B2 (en) 2004-05-06 2010-09-21 Smp Logic Systems Llc Manufacturing execution system for validation, quality and risk assessment and monitoring of pharmaceutical manufacturing processes
TWI428271B (zh) * 2004-06-09 2014-03-01 Smithkline Beecham Corp 生產藥物之裝置及方法
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
EP2178540A4 (de) * 2007-08-01 2012-01-04 Stellan Hjerten Pharmazeutische zusammensetzung zur adsorption auf der zelloberfläche von pathogenen mikroben
US8288342B2 (en) * 2008-10-10 2012-10-16 Teva Women's Health, Inc. Methods for treating vasomotor symptoms in castrated prostatic cancer patients with low dose cyproterone acetate
EP2405905B1 (de) * 2009-03-09 2016-06-29 SPI Pharma, INC. Hoch verdichtungsfähige und beständige direktkompressionshilfsstoffe und hilfsstoffsysteme
HUP0900698A2 (en) 2009-11-06 2011-06-28 Richter Gedeon Nyrt Pharmaceutical compositions of enhanced stability containing drospirenone and ethynyl estradiol and process for their preparation
EP2354150A1 (de) * 2010-02-09 2011-08-10 Laboratoire Theramex Verfahren zur Herstellung von Gestoden
WO2012120365A1 (en) 2011-03-07 2012-09-13 Aurobindo Pharma Limited Stable pharmaceutical composition comprising ethinyl estradiol
CN102416003A (zh) * 2011-12-08 2012-04-18 南京优科生物医药有限公司 一种制备恩替卡韦片剂的方法
WO2014137877A1 (en) * 2013-03-04 2014-09-12 Besins Healthcare Luxembourg Sarl Dry pharmaceutical compositions comprising active agent nanoparticles bound to carrier particles

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3626063A (en) * 1959-08-11 1971-12-07 Upjohn Co Therapeutic compositions comprising 6-fluoro-16-methyl prednisolone, the 21 acylates and salts thereof
US3344030A (en) * 1964-06-15 1967-09-26 American Home Prod Reinforced directly compressed nongranulated pharmaceutical crystalline lactose tables
US3423507A (en) * 1966-02-25 1969-01-21 Schering Corp Method of treating benign prostratic hypertrophy
US3568828A (en) * 1967-03-01 1971-03-09 Squibb & Sons Inc Modified sequential oral contraceptive
US3671633A (en) * 1971-05-10 1972-06-20 American Cyanamid Co Process for tabletting acetazolamide
US3802914A (en) * 1972-04-10 1974-04-09 Kraftco Corp Method of treating lactose
SE378109B (de) * 1972-05-19 1975-08-18 Bofors Ab
DE2365103C3 (de) * 1973-12-21 1980-08-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen V erwendung von Hormonen zur Kontrazeption
DE2524902C2 (de) * 1975-06-02 1984-10-25 Schering AG, 1000 Berlin und 4709 Bergkamen Vorrichtung zur Inhalation von Arzneimitteln
US4143136A (en) * 1976-11-20 1979-03-06 Akzona Incorporated Method of contraception
DE2716323C2 (de) * 1977-04-07 1986-03-13 Schering AG, 1000 Berlin und 4709 Bergkamen Vorrichtung zur Inhalation von Arzneimitteln
NL8001593A (nl) * 1980-03-18 1981-10-16 Akzo Nv Meerfasisch combinatiepreparaat voor orale anticonceptie.
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
DE3506276C1 (de) * 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
US4916163A (en) * 1985-06-04 1990-04-10 The Upjohn Company Spray-dried lactose formulation of micronized glyburide

Also Published As

Publication number Publication date
ZA921659B (en) 1992-11-25
CA2062428A1 (en) 1992-09-13
AU1211992A (en) 1992-09-17
DK0503521T4 (da) 2005-12-05
KR100198017B1 (ko) 1999-06-15
ES2077897T5 (es) 2006-06-16
JP3474210B2 (ja) 2003-12-08
NZ241915A (en) 1994-04-27
FI100770B (fi) 1998-02-27
CN1064810A (zh) 1992-09-30
ATE125155T1 (de) 1995-08-15
IE67345B1 (en) 1996-03-20
DE69203488D1 (de) 1995-08-24
KR920017656A (ko) 1992-10-21
NO305055B1 (no) 1999-03-29
ES2077897T3 (es) 1995-12-01
NO920958L (no) 1992-09-14
EP0503521B1 (de) 1995-07-19
DE69203488T3 (de) 2006-07-06
IE920634A1 (en) 1992-09-23
AU651869B2 (en) 1994-08-04
JPH0578251A (ja) 1993-03-30
DK0503521T3 (da) 1995-11-27
NO920958D0 (no) 1992-03-11
FI921023A (fi) 1992-09-13
EP0503521B2 (de) 2005-11-09
EP0503521A1 (de) 1992-09-16
US5382434A (en) 1995-01-17
CN1039086C (zh) 1998-07-15
CA2062428C (en) 2002-07-30
GR3017737T3 (en) 1996-01-31
HK1002018A1 (en) 1998-07-24
FI921023A0 (fi) 1992-03-09

Similar Documents

Publication Publication Date Title
DE69203488D1 (de) Niedrigdosierte getrocknete pharmazeutische Präparate.
IE891414L (en) Pharmaceutical compositions
KR890001526A (ko) 경구용 서방성 아세트 아미노펜 제형 및 이의 제조방법
CA2152795A1 (en) Readily available konjac glucomannan sustained release excipient
RU93036959A (ru) Свободно растворимый лекарственный препарат с замедленным действием биологически активных веществ, назначенный для приема внутрь, способ его производства
NO922807D0 (no) Farmasoeytiske dideoksypurinnukleosid-preparater til oraltbruk
ES2076358T3 (es) Granulados con elevado contenido de ibuprofeno.
EP0391374A3 (de) Verfahren zur Herstellung von Bromocriptin enthaltenden Arzneimittelzubereitungen mit hoher Stabilität und in Beziehung zueinander stehende Produkte
KR880004805A (ko) 분무건조된 아세트아미노펜
HU9302971D0 (en) Chewable antacid preparations
DK0483320T3 (da) Farmaceutiske sammensætninger med forlænget frigivelse til peroral indgivelse og fremgangsmåde til fremstilling deraf
DE68907091T2 (de) Scleroglucan und Wirkstoff enthaltende pharmazeutische Tabletten und Kapselgranulate.
NO176948C (no) Fremgangsmåte for fremstilling av et farmasöytisk preparat i enhetsdoseform omfattende finmalt colestipol-hydroklorid
WO2001010415B1 (en) A binder for pharmaceutical compositions
Fateeva Pharmacokinetics of amphoglucamine in an experiment
JPS57176907A (en) Readily absorbable solid pharmaceutical composition of as-56c
CA2176461A1 (en) Method for preparing low dose pharmaceutical products

Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: N.V. ORGANON, OSS, NL