DE69130071D1 - Zusammensetzung verwendbar als therapeutisches mittel gegen chronische virale leberkrankheiten - Google Patents

Zusammensetzung verwendbar als therapeutisches mittel gegen chronische virale leberkrankheiten

Info

Publication number
DE69130071D1
DE69130071D1 DE69130071T DE69130071T DE69130071D1 DE 69130071 D1 DE69130071 D1 DE 69130071D1 DE 69130071 T DE69130071 T DE 69130071T DE 69130071 T DE69130071 T DE 69130071T DE 69130071 D1 DE69130071 D1 DE 69130071D1
Authority
DE
Germany
Prior art keywords
therapeutic agent
chronic viral
composition used
liver diseases
agent against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69130071T
Other languages
English (en)
Other versions
DE69130071T3 (de
DE69130071T2 (de
Inventor
Hans Thoma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medeva Holdings BV
Original Assignee
Medeva Holdings BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8204863&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69130071(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medeva Holdings BV filed Critical Medeva Holdings BV
Publication of DE69130071D1 publication Critical patent/DE69130071D1/de
Application granted granted Critical
Publication of DE69130071T2 publication Critical patent/DE69130071T2/de
Publication of DE69130071T3 publication Critical patent/DE69130071T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69130071T 1990-12-19 1991-12-19 Zusammensetzung verwendbar als therapeutisches mittel gegen chronische virale leberkrankheiten Expired - Lifetime DE69130071T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP90124775A EP0491077A1 (de) 1990-12-19 1990-12-19 Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten
EP90124775 1990-12-19
PCT/EP1991/002460 WO1992011368A1 (en) 1990-12-19 1991-12-19 A composition used as a therapeutic agent against chronic viral hepatic diseases

Publications (3)

Publication Number Publication Date
DE69130071D1 true DE69130071D1 (de) 1998-10-01
DE69130071T2 DE69130071T2 (de) 1999-01-07
DE69130071T3 DE69130071T3 (de) 2008-02-21

Family

ID=8204863

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130071T Expired - Lifetime DE69130071T3 (de) 1990-12-19 1991-12-19 Zusammensetzung verwendbar als therapeutisches mittel gegen chronische virale leberkrankheiten

Country Status (15)

Country Link
US (2) US6020167A (de)
EP (2) EP0491077A1 (de)
JP (2) JP3857305B2 (de)
KR (1) KR0156587B1 (de)
AT (1) ATE170220T1 (de)
AU (1) AU657935B2 (de)
CA (1) CA2098021C (de)
CZ (1) CZ290233B6 (de)
DE (1) DE69130071T3 (de)
DK (1) DK0563093T4 (de)
ES (1) ES2121000T5 (de)
HK (1) HK1002901A1 (de)
HU (1) HU216301B (de)
SK (1) SK280551B6 (de)
WO (1) WO1992011368A1 (de)

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DE4107612A1 (de) 1991-03-09 1992-09-10 Behringwerke Ag Rekombinante proteine mit der immunreaktivitaet des hepatitis b virus e antigens (hbeag), verfahren zu ihrer herstellung und ihre verwendung in immunoassays und impfstoffen
US7611713B2 (en) 1993-03-05 2009-11-03 Pharmexa Inc. Inducing cellular immune responses to hepatitis B virus using peptide compositions
US6689363B1 (en) 1992-01-29 2004-02-10 Epimmune Inc. Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
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US7091324B2 (en) 1998-11-05 2006-08-15 Board Of Trustees Of Leland Stanford Junior University Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes
ATE339211T1 (de) 2000-03-29 2006-10-15 Univ Georgetown L-fmau zur behandlung von hepatitis-delta-virus- infizierung
IL142802A (en) * 2000-04-27 2015-01-29 Enzo Therapeutics Inc Use of one or more HBV antigens for the preparation of oral pharmaceutical preparations for the treatment of a person with active HBV infection or hepatocellular carcinoma
US6787526B1 (en) 2000-05-26 2004-09-07 Idenix Pharmaceuticals, Inc. Methods of treating hepatitis delta virus infection with β-L-2′-deoxy-nucleosides
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US7351413B2 (en) * 2002-02-21 2008-04-01 Lorantis, Limited Stabilized HBc chimer particles as immunogens for chronic hepatitis
KR100708398B1 (ko) * 2002-03-22 2007-04-18 (주) 에이프로젠 인간화 항체 및 이의 제조방법
DE10339927A1 (de) * 2003-08-29 2005-03-24 Rhein Biotech Gesellschaft für neue Biotechnologische Prozesse und Produkte mbH Zusammensetzung zur Prophylaxe/Therapie von HBV-Infektionen und HBV-vermittelten Erkrankungen
CA2549865A1 (en) * 2003-11-12 2005-06-02 Hbv Theranostica Ab Methods and means relating to hepatitis b infection
GB0326416D0 (en) 2003-11-12 2003-12-17 Karolinska Innovations Ab Methods and means relating to hepatitis B infection
PL1802746T3 (pl) * 2004-10-27 2011-10-31 Crucell Switzerland Ag Cząstki wirosomu zawierające antygeny wirusa grypy i wirusa zapalenia wątroby typu B
EP2185195A2 (de) * 2007-08-16 2010-05-19 Tripep Ab Immunogen-plattform
WO2009092396A1 (en) 2008-01-25 2009-07-30 Universitätsklinikum Heidelberg Hydrophobic modified pres-derived peptides of hepatitis b virus (hbv) and their use as hbv and hdv entry inhibitors
CN101485672B (zh) * 2008-12-05 2010-08-25 广东粤龙药业有限公司 异丙景糖酐在制备治疗人HBeAg阳性慢性乙型肝炎药物中的应用
NZ598000A (en) 2009-08-07 2013-10-25 Transgene Sa Composition for treating hbv infection
US10076570B2 (en) 2009-08-07 2018-09-18 Transgene S.A. Composition for treating HBV infection

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Also Published As

Publication number Publication date
EP0491077A1 (de) 1992-06-24
EP0563093A1 (de) 1993-10-06
JP2001019643A (ja) 2001-01-23
HU216301B (hu) 1999-06-28
EP0563093B1 (de) 1998-08-26
KR0156587B1 (en) 1998-10-15
DK0563093T3 (da) 1999-02-08
CZ290233B6 (cs) 2002-06-12
CA2098021C (en) 2000-04-25
AU9081791A (en) 1992-07-22
SK280551B6 (sk) 2000-03-13
DE69130071T3 (de) 2008-02-21
EP0563093B2 (de) 2007-10-03
DE69130071T2 (de) 1999-01-07
AU657935B2 (en) 1995-03-30
US20030235591A1 (en) 2003-12-25
ES2121000T3 (es) 1998-11-16
ES2121000T5 (es) 2008-04-16
CZ118693A3 (en) 1994-02-16
DK0563093T4 (da) 2008-01-21
HK1002901A1 (en) 1998-09-25
ATE170220T1 (de) 1998-09-15
HUT66437A (en) 1994-11-28
SK63693A3 (en) 1993-10-06
WO1992011368A1 (en) 1992-07-09
JPH06507303A (ja) 1994-08-25
US6020167A (en) 2000-02-01
JP3857305B2 (ja) 2006-12-13
HU9301794D0 (en) 1993-10-28
CA2098021A1 (en) 1992-06-20

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