DE69031665D1 - Nachweis von Nukleinsäuresequenzen unter Verwendung von Fluoreszenz-Polarisation - Google Patents

Nachweis von Nukleinsäuresequenzen unter Verwendung von Fluoreszenz-Polarisation

Info

Publication number
DE69031665D1
DE69031665D1 DE69031665T DE69031665T DE69031665D1 DE 69031665 D1 DE69031665 D1 DE 69031665D1 DE 69031665 T DE69031665 T DE 69031665T DE 69031665 T DE69031665 T DE 69031665T DE 69031665 D1 DE69031665 D1 DE 69031665D1
Authority
DE
Germany
Prior art keywords
nucleic acid
detection
acid sequences
fluorescence polarization
detect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69031665T
Other languages
English (en)
Other versions
DE69031665T2 (de
Inventor
Andrew John Garman
Robert Stanley Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GARMAN, ANDREW, ASHTON, CHESTER, GB
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of DE69031665D1 publication Critical patent/DE69031665D1/de
Application granted granted Critical
Publication of DE69031665T2 publication Critical patent/DE69031665T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hybrid Electric Vehicles (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Surgical Instruments (AREA)
  • Transducers For Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
DE69031665T 1989-02-07 1990-02-02 Nachweis von Nukleinsäuresequenzen unter Verwendung von Fluoreszenz-Polarisation Expired - Fee Related DE69031665T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898902689A GB8902689D0 (en) 1989-02-07 1989-02-07 Assay method

Publications (2)

Publication Number Publication Date
DE69031665D1 true DE69031665D1 (de) 1997-12-11
DE69031665T2 DE69031665T2 (de) 1998-02-26

Family

ID=10651255

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69031665T Expired - Fee Related DE69031665T2 (de) 1989-02-07 1990-02-02 Nachweis von Nukleinsäuresequenzen unter Verwendung von Fluoreszenz-Polarisation

Country Status (14)

Country Link
US (1) US6022686A (de)
EP (1) EP0382433B1 (de)
JP (1) JPH02295496A (de)
AT (1) ATE159984T1 (de)
AU (1) AU4902590A (de)
CA (1) CA2009454C (de)
DE (1) DE69031665T2 (de)
ES (1) ES2109226T3 (de)
FI (1) FI900602A0 (de)
GB (2) GB8902689D0 (de)
IE (1) IE900442L (de)
IL (1) IL93297A0 (de)
NO (1) NO900582L (de)
ZA (1) ZA90912B (de)

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US5445935A (en) * 1992-11-23 1995-08-29 Royer; Catherine A. Quantitative detection of macromolecules with fluorescent oligonucleotides
ATE319853T1 (de) * 1992-11-27 2006-03-15 Canon Kk Verfahren und sonde zum nachweis von nukleinsäuren
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CA2145719C (en) * 1994-04-18 1998-06-30 James G. Nadeau Detection of nucleic acid amplification
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AU705637B2 (en) * 1994-09-23 1999-05-27 Becton Dickinson & Company Detection of nucleic acid amplification
GB9510262D0 (en) * 1995-05-22 1995-07-19 Nat Blood Authority The Detection method
CA2205057C (en) * 1995-09-12 2001-12-11 Hugh V. Cottingham Device and method for dna amplification and assay
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US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US5800989A (en) * 1995-11-15 1998-09-01 Becton, Dickinson And Company Method for detection of nucleic acid targets by amplification and fluorescence polarization
US5641633A (en) * 1995-11-15 1997-06-24 Becton, Dickinson And Company Fluorescence polarization detection of nucleic acids
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US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US6503709B1 (en) 1997-07-03 2003-01-07 Id Biomedical Corporation Methods for rapidly detecting methicillin resistant staphylococci
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US6261781B1 (en) 1997-08-05 2001-07-17 Wisconsin Alumni Research Foundation Direct detection and mutation analysis of low copy number nucleic acids
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
WO1999060158A1 (fr) * 1998-05-19 1999-11-25 Laboratory Of Molecular Biophotonics Phase solide utilisee pour detecter de l'acide nucleique et procede de detection d'acide nucleique
JP3437094B2 (ja) * 1998-07-03 2003-08-18 松下電器産業株式会社 多波長蛍光偏光法
US6180408B1 (en) * 1998-08-21 2001-01-30 Washington University Fluorescence polarization in nucleic acid analysis
FR2784748A1 (fr) * 1998-10-19 2000-04-21 Revelgenics Detection de reactions de polymerisation par polarisation de fluorescence
US6100039A (en) * 1999-01-28 2000-08-08 Panvera, Inc. Process for reverse transcriptase activity measurement using fluorescence polarization
JP2003527075A (ja) 1999-03-25 2003-09-16 ハイセック，インコーポレーテッド ハイブリダイゼーションによる配列分析のための、溶液ベースの方法
ATE409238T1 (de) * 2000-05-12 2008-10-15 Caliper Life Sciences Inc Nachweis der hybridisierung von nukleinsäuren durch fluoreszenzpolarisation
US7422850B2 (en) * 2000-05-19 2008-09-09 Eragen Biosciences, Inc. Materials and methods for detection of nucleic acids
US6977161B2 (en) 2000-10-14 2005-12-20 Eragen Biosciences, Inc. Solid support assay systems and methods utilizing non-standard bases
US6258546B1 (en) * 2000-06-23 2001-07-10 Becton, Dickinson And Company Detection of nucleic acid amplification
AU2002227982A1 (en) * 2000-12-05 2002-06-18 Syngenta Participations Ag Method and kit for identification of nucleic acid modification enzymes and inhibitors thereof
DE10104938B4 (de) * 2001-01-29 2005-06-23 Epigenomics Ag Fluoreszenzpolarisation 1
DE10104937B4 (de) * 2001-01-29 2005-03-17 Epigenomics Ag Fluoreszenzpolarisation 2
US8148171B2 (en) 2001-10-09 2012-04-03 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US6589744B2 (en) 2001-11-26 2003-07-08 Syngenta Participations Ag Method and kit for identification for nucleic acid modification enzymes and inhibitors thereof
CA2498713A1 (en) * 2002-09-17 2004-04-01 Richard Abraham Joseph Real-time detection of nucleic acid reactions
JP4621197B2 (ja) 2003-01-17 2011-01-26 エラジェン バイオサイエンシズ インコーポレイテッド 非標準塩基を用いた核酸増幅
KR100890885B1 (ko) 2003-03-31 2009-03-31 에프. 호프만-라 로슈 아게 일본 뇌염 바이러스 혈청군의 구성원을 포함하는, 특정플라비바이러스 검출용 조성물 및 방법
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DE602004026111D1 (de) 2003-12-19 2010-04-29 Nat Inst Of Advanced Ind Scien Verfahren zum testen von nukleinsäuren unter verwendung davon sowie dafür zu verwendende nukleinsäuresonde
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
US7851152B2 (en) * 2004-09-25 2010-12-14 Yaodong Chen Fluorescent base analogues' usage in the characterization of nucleic acid molecules and their interactions
US20060172314A1 (en) * 2005-01-31 2006-08-03 Song Min-Sun Quantification of amplified nucleic acids
WO2006101913A2 (en) 2005-03-18 2006-09-28 Eragen Biosciences, Inc. Methods for detecting multiple species and subspecies of neiserria
JP4650420B2 (ja) * 2005-03-30 2011-03-16 東洋紡績株式会社 塩基判定方法及び塩基判定用キット
CA2610863C (en) 2005-06-07 2017-01-17 Eragen Biosciences, Inc. Methods for detection and typing of nucleic acids
JP2007330134A (ja) * 2006-06-14 2007-12-27 Toyobo Co Ltd 核酸の検出方法
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
US20110059431A1 (en) * 2007-06-18 2011-03-10 Northwestern University Non-enzymatic detection of bacterial genomic dna
WO2010112033A2 (en) 2009-03-31 2010-10-07 Østjysk Innovation A/S Method for estimating the risk of having or developing multiple sclerosis using sequence polymorphisms in a specific region of chromosome x
CA2778449C (en) 2009-10-23 2017-06-20 Luminex Corporation Amplification primers with non-standard bases for increased reaction specificity
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EP2948566A4 (de) * 2013-01-24 2016-10-05 California Inst Of Techn Chromophorenbasierte charakterisierungs- und erkennungsverfahren

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Also Published As

Publication number Publication date
ZA90912B (en) 1990-10-31
EP0382433A3 (de) 1992-01-15
GB9002536D0 (en) 1990-04-04
EP0382433A2 (de) 1990-08-16
ES2109226T3 (es) 1998-01-16
FI900602A0 (fi) 1990-02-07
AU4902590A (en) 1990-08-16
CA2009454C (en) 2000-04-04
IL93297A0 (en) 1990-11-29
US6022686A (en) 2000-02-08
GB8902689D0 (en) 1989-03-30
ATE159984T1 (de) 1997-11-15
GB2228998A (en) 1990-09-12
NO900582L (no) 1990-08-08
GB2228998B (en) 1993-04-07
DE69031665T2 (de) 1998-02-26
IE900442L (en) 1990-08-07
JPH02295496A (ja) 1990-12-06
NO900582D0 (no) 1990-02-07
CA2009454A1 (en) 1990-08-07
EP0382433B1 (de) 1997-11-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASTRAZENECA UK LTD., LONDON, GB

8327 Change in the person/name/address of the patent owner

Owner name: GARMAN, ANDREW, ASHTON, CHESTER, GB

8339 Ceased/non-payment of the annual fee