DE69029276D1 - Verfahren zur diagnostizierung von menschlicher grippe und in position 4 modifizierte chromogene n-acetylneuraminsäure substrate zur verwendung in diesen verfahren - Google Patents

Verfahren zur diagnostizierung von menschlicher grippe und in position 4 modifizierte chromogene n-acetylneuraminsäure substrate zur verwendung in diesen verfahren

Info

Publication number
DE69029276D1
DE69029276D1 DE69029276T DE69029276T DE69029276D1 DE 69029276 D1 DE69029276 D1 DE 69029276D1 DE 69029276 T DE69029276 T DE 69029276T DE 69029276 T DE69029276 T DE 69029276T DE 69029276 D1 DE69029276 D1 DE 69029276D1
Authority
DE
Germany
Prior art keywords
chromogenic
hydroxyl group
diagnosticing
methods
influenza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029276T
Other languages
English (en)
Other versions
DE69029276T2 (de
Inventor
Gregory Turner
James Maher
C Clinkscales
Michael Roark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oklahoma Medical Research Foundation
Original Assignee
Symex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symex Corp filed Critical Symex Corp
Publication of DE69029276D1 publication Critical patent/DE69029276D1/de
Application granted granted Critical
Publication of DE69029276T2 publication Critical patent/DE69029276T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
DE69029276T 1989-12-29 1990-12-27 Verfahren zur diagnostizierung von menschlicher grippe und in position 4 modifizierte chromogene n-acetylneuraminsäure substrate zur verwendung in diesen verfahren Expired - Fee Related DE69029276T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45880589A 1989-12-29 1989-12-29
PCT/US1990/007681 WO1991009972A1 (en) 1989-12-29 1990-12-27 Methods for diagnosting human influenza and 4-position modified chromogenic n-acetylneuraminic acid substrates for use therein

Publications (2)

Publication Number Publication Date
DE69029276D1 true DE69029276D1 (de) 1997-01-09
DE69029276T2 DE69029276T2 (de) 1997-04-17

Family

ID=23822154

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029276T Expired - Fee Related DE69029276T2 (de) 1989-12-29 1990-12-27 Verfahren zur diagnostizierung von menschlicher grippe und in position 4 modifizierte chromogene n-acetylneuraminsäure substrate zur verwendung in diesen verfahren

Country Status (10)

Country Link
EP (1) EP0507854B1 (de)
JP (1) JP3134999B2 (de)
AT (1) ATE145673T1 (de)
AU (1) AU656721B2 (de)
CA (1) CA2072368C (de)
DE (1) DE69029276T2 (de)
DK (1) DK0507854T3 (de)
ES (1) ES2097804T3 (de)
GR (1) GR3022421T3 (de)
WO (1) WO1991009972A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69131504T2 (de) * 1990-12-31 1999-11-18 Oklahoma Med Res Found Verfahren zum visuellen nachweis der anwesenheit eines virus in einer klinischen probe
JPH09509664A (ja) * 1994-02-25 1997-09-30 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー ４−ｎ−置換シアル酸およびそれらのシアロシド類
US5556963A (en) * 1994-08-05 1996-09-17 Oklahoma Medical Research Foundation Synthesis of 4-alkoxy-N-acetylneuraminic acid
DE69721242T2 (de) * 1996-03-01 2004-01-29 Biota Scient Management Verfahren zum nachweis von influenza-virus und dazu verwendbare verbindungen
US5719020A (en) * 1996-09-25 1998-02-17 Oklahoma Medical Research Foundation 4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens
US6303764B1 (en) 1998-09-24 2001-10-16 Zymetx, Inc. Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
JP2003522113A (ja) * 1998-10-27 2003-07-22 ユーエービー リサーチ ファンデイション シアリダーゼの発色基質とその製造法および使用法
US6555698B1 (en) * 1998-11-17 2003-04-29 Tropix, Inc. Chemiluminescent substrates for neuraminidase, assays for detection of neuraminidase and kits therefor
US6420552B1 (en) 1999-09-10 2002-07-16 Zymetx, Inc. Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
JPWO2006064914A1 (ja) * 2004-12-17 2008-06-12 独立行政法人産業技術総合研究所 ノイラミニダーゼ阻害剤
BR112015025042B1 (pt) * 2013-04-01 2023-11-14 Becton, Dickinson And Company Sistema de diagnóstico e método para detectar vírus influenza, composto inibidor de máscara e kit
EP3149212B1 (de) * 2014-05-30 2020-08-26 Georgia State University Research Foundation, Inc. Elektrochemische verfahren und verbindungen zur detektion von enzymen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009975A1 (en) * 1989-12-29 1991-07-11 Symex Corp. Chromogenic 7- or 8-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith
WO1991010744A1 (en) * 1990-01-10 1991-07-25 Symex Corp. Chromogenic 9-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith

Also Published As

Publication number Publication date
EP0507854A4 (en) 1992-10-21
EP0507854B1 (de) 1996-11-27
JP3134999B2 (ja) 2001-02-13
DK0507854T3 (da) 1997-05-12
AU656721B2 (en) 1995-02-16
ATE145673T1 (de) 1996-12-15
CA2072368C (en) 1998-06-30
CA2072368A1 (en) 1991-06-30
ES2097804T3 (es) 1997-04-16
EP0507854A1 (de) 1992-10-14
DE69029276T2 (de) 1997-04-17
AU7164791A (en) 1991-07-24
GR3022421T3 (en) 1997-04-30
WO1991009972A1 (en) 1991-07-11
JPH05505099A (ja) 1993-08-05

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: OKLAHOMA MEDICAL RESEARCH FOUNDATION, OKLAHOMA, OK

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee