FI942075A - Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina - Google Patents

Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina Download PDF

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Publication number
FI942075A
FI942075A FI942075A FI942075A FI942075A FI 942075 A FI942075 A FI 942075A FI 942075 A FI942075 A FI 942075A FI 942075 A FI942075 A FI 942075A FI 942075 A FI942075 A FI 942075A
Authority
FI
Finland
Prior art keywords
derivatives
compounds
preparation
bile acid
medicaments
Prior art date
Application number
FI942075A
Other languages
English (en)
Swedish (sv)
Other versions
FI942075A0 (fi
Inventor
Alfons Enhsen
Heiner Glombik
Werner Kramer
Guenther Wess
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI942075A0 publication Critical patent/FI942075A0/fi
Publication of FI942075A publication Critical patent/FI942075A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI942075A 1993-05-08 1994-05-05 Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina FI942075A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4315368 1993-05-08

Publications (2)

Publication Number Publication Date
FI942075A0 FI942075A0 (fi) 1994-05-05
FI942075A true FI942075A (fi) 1994-11-09

Family

ID=6487579

Family Applications (1)

Application Number Title Priority Date Filing Date
FI942075A FI942075A (fi) 1993-05-08 1994-05-05 Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina

Country Status (19)

Country Link
US (1) US5466815A (fi)
EP (1) EP0624596B1 (fi)
JP (1) JP3476157B2 (fi)
KR (1) KR100333149B1 (fi)
AT (1) ATE163938T1 (fi)
AU (1) AU666440B2 (fi)
CA (1) CA2123048C (fi)
CY (1) CY2119B1 (fi)
CZ (1) CZ289515B6 (fi)
DE (1) DE59405410D1 (fi)
DK (1) DK0624596T3 (fi)
ES (1) ES2115096T3 (fi)
FI (1) FI942075A (fi)
GR (1) GR3026496T3 (fi)
HU (1) HU217439B (fi)
IL (1) IL109581A (fi)
NO (1) NO304795B1 (fi)
NZ (1) NZ260469A (fi)
TW (1) TW289757B (fi)

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CN108601744B (zh) 2016-02-09 2022-01-04 阿尔比里奥公司 口服考来烯胺制剂及其用途
JP6954927B2 (ja) 2016-02-09 2021-10-27 アルビレオ・アクチボラグ 経口コレスチラミン製剤及びその使用
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KR20230106651A (ko) 2020-11-12 2023-07-13 알비레오 에이비 진행성 가족성 간내 담즙정체증(pfic)을 치료하기 위한 오데빅시바트
EP4255565A1 (en) 2020-12-04 2023-10-11 Albireo AB Benzothia(di)azepine compounds and their use as bile acid modulators
TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3930696A1 (de) * 1989-09-14 1991-03-28 Hoechst Ag Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
US5250524A (en) * 1990-12-06 1993-10-05 Hoechst Aktiengesellschaft Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals

Also Published As

Publication number Publication date
AU6194794A (en) 1994-11-10
EP0624596A2 (de) 1994-11-17
ATE163938T1 (de) 1998-03-15
FI942075A0 (fi) 1994-05-05
ES2115096T3 (es) 1998-06-16
HU217439B (hu) 2000-01-28
HU9401443D0 (en) 1994-08-29
CA2123048A1 (en) 1994-11-09
TW289757B (fi) 1996-11-01
EP0624596A3 (de) 1995-06-07
CA2123048C (en) 2005-11-29
KR100333149B1 (ko) 2002-09-19
IL109581A0 (en) 1994-08-26
JP3476157B2 (ja) 2003-12-10
NO941677D0 (no) 1994-05-06
CY2119B1 (en) 2002-04-26
EP0624596B1 (de) 1998-03-11
GR3026496T3 (en) 1998-07-31
NO304795B1 (no) 1999-02-15
IL109581A (en) 1998-03-10
HUT67390A (en) 1995-04-28
NZ260469A (en) 1995-03-28
AU666440B2 (en) 1996-02-08
CZ113594A3 (en) 1994-12-15
DK0624596T3 (da) 1998-10-07
CZ289515B6 (cs) 2002-02-13
NO941677L (no) 1994-11-09
JPH06329695A (ja) 1994-11-29
DE59405410D1 (de) 1998-04-16
US5466815A (en) 1995-11-14

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