DE69025845D1 - Rekombinante DNA-Expressionsvektoren und DNA-Komponenten, die für eine Acyltransferase-Aktivität von Aspergillus kodieren - Google Patents

Rekombinante DNA-Expressionsvektoren und DNA-Komponenten, die für eine Acyltransferase-Aktivität von Aspergillus kodieren

Info

Publication number
DE69025845D1
DE69025845D1 DE69025845T DE69025845T DE69025845D1 DE 69025845 D1 DE69025845 D1 DE 69025845D1 DE 69025845 T DE69025845 T DE 69025845T DE 69025845 T DE69025845 T DE 69025845T DE 69025845 D1 DE69025845 D1 DE 69025845D1
Authority
DE
Germany
Prior art keywords
expression vectors
acyltransferase activity
recombinant dna
dna
encoding aspergillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69025845T
Other languages
English (en)
Other versions
DE69025845T2 (de
Inventor
James Robert Miller
Paul Luther Skatrud
Matthew Barry Tobin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69025845D1 publication Critical patent/DE69025845D1/de
Application granted granted Critical
Publication of DE69025845T2 publication Critical patent/DE69025845T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69025845T 1989-09-27 1990-09-25 Rekombinante DNA-Expressionsvektoren und DNA-Komponenten, die für eine Acyltransferase-Aktivität von Aspergillus kodieren Expired - Fee Related DE69025845T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41340189A 1989-09-27 1989-09-27

Publications (2)

Publication Number Publication Date
DE69025845D1 true DE69025845D1 (de) 1996-04-18
DE69025845T2 DE69025845T2 (de) 1996-10-31

Family

ID=23637073

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69025845T Expired - Fee Related DE69025845T2 (de) 1989-09-27 1990-09-25 Rekombinante DNA-Expressionsvektoren und DNA-Komponenten, die für eine Acyltransferase-Aktivität von Aspergillus kodieren

Country Status (9)

Country Link
EP (1) EP0422790B1 (de)
JP (1) JPH03133384A (de)
AT (1) ATE135399T1 (de)
CA (1) CA2026262A1 (de)
DE (1) DE69025845T2 (de)
DK (1) DK0422790T3 (de)
ES (1) ES2086374T3 (de)
GR (1) GR3019852T3 (de)
IL (1) IL95766A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
RO116648B1 (ro) * 1991-10-15 2001-04-30 Merck & Co Inc Bioprocedeu pentru prepararea acidului 7-amino-3-deacetil-cefalosporanic si a acidului 7-aminocefalosporanic
ATE334203T1 (de) * 1994-09-28 2006-08-15 Novozymes As Verfahren zur herstellung von sekundären metaboliten
JP2000514301A (ja) * 1996-07-16 2000-10-31 ギスト ブロカデス ベスローテン フェンノートシャップ アクレモニウム・クリソゲヌムを用いたセファロスポリンの新規な調製方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208845B (en) * 1988-04-08 1994-01-28 Biochemie Gmbh Process for producing penicillin acyle-transferase its coding dna sequence vector containing it and host cell transformated thereby

Also Published As

Publication number Publication date
JPH03133384A (ja) 1991-06-06
ES2086374T3 (es) 1996-07-01
CA2026262A1 (en) 1991-03-28
GR3019852T3 (en) 1996-08-31
EP0422790A2 (de) 1991-04-17
IL95766A0 (en) 1991-06-30
EP0422790B1 (de) 1996-03-13
ATE135399T1 (de) 1996-03-15
EP0422790A3 (en) 1991-08-21
IL95766A (en) 1996-12-05
DK0422790T3 (da) 1996-05-06
DE69025845T2 (de) 1996-10-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee