ATE135399T1 - Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren - Google Patents

Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren

Info

Publication number
ATE135399T1
ATE135399T1 AT90310448T AT90310448T ATE135399T1 AT E135399 T1 ATE135399 T1 AT E135399T1 AT 90310448 T AT90310448 T AT 90310448T AT 90310448 T AT90310448 T AT 90310448T AT E135399 T1 ATE135399 T1 AT E135399T1
Authority
AT
Austria
Prior art keywords
aspergillus
expression vectors
acyltransferase activity
recombinant dna
dna
Prior art date
Application number
AT90310448T
Other languages
English (en)
Inventor
James Robert Miller
Paul Luther Skatrud
Matthew Barry Tobin
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE135399T1 publication Critical patent/ATE135399T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90310448T 1989-09-27 1990-09-25 Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren ATE135399T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41340189A 1989-09-27 1989-09-27

Publications (1)

Publication Number Publication Date
ATE135399T1 true ATE135399T1 (de) 1996-03-15

Family

ID=23637073

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90310448T ATE135399T1 (de) 1989-09-27 1990-09-25 Rekombinante dna-expressionsvektoren und dna- komponenten, die für eine acyltransferase- aktivität von aspergillus kodieren

Country Status (9)

Country Link
EP (1) EP0422790B1 (de)
JP (1) JPH03133384A (de)
AT (1) ATE135399T1 (de)
CA (1) CA2026262A1 (de)
DE (1) DE69025845T2 (de)
DK (1) DK0422790T3 (de)
ES (1) ES2086374T3 (de)
GR (1) GR3019852T3 (de)
IL (1) IL95766A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
KR100227711B1 (ko) * 1991-10-15 1999-12-01 한스 발터 라벤 7-아미노세팔로스포란산 및 7-아미노데아세틸세팔로스포란산 제조를 위한 신규한 생물학적 공정
ATE334203T1 (de) * 1994-09-28 2006-08-15 Novozymes As Verfahren zur herstellung von sekundären metaboliten
AU4201897A (en) * 1996-07-16 1998-02-09 Gist-Brocades B.V. Novel process for the preparation of cephalosporins using (acremonium chrysogenum)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR900700610A (ko) * 1988-04-08 1990-08-16 죠지 그렐리니 β-락탐 화합물의 생성을 위한 유전자 및 유전자 생성물

Also Published As

Publication number Publication date
EP0422790B1 (de) 1996-03-13
GR3019852T3 (en) 1996-08-31
IL95766A (en) 1996-12-05
DE69025845D1 (de) 1996-04-18
EP0422790A2 (de) 1991-04-17
DE69025845T2 (de) 1996-10-31
JPH03133384A (ja) 1991-06-06
DK0422790T3 (da) 1996-05-06
CA2026262A1 (en) 1991-03-28
IL95766A0 (en) 1991-06-30
ES2086374T3 (es) 1996-07-01
EP0422790A3 (en) 1991-08-21

Similar Documents

Publication Publication Date Title
DE69227116D1 (de) Hochstabile rekombinante hefen für die herstellung von rekombinanten proteinen
DE69226167T2 (de) Strukturgen von pneumokokken-protein
DE3650664T2 (de) Verwendung von promotoren von filamentösen pilzen
DE69022595D1 (de) Herstellung von kohlefaser-halbfabrikaten.
DE68923123D1 (de) Herstellung von Proteinen.
ATE140962T1 (de) Dns-klone von menschlichem thrombomodulin
ATE118042T1 (de) Rekombinante dna enthaltende expressionsvektoren und für isopenicillin-n-epimerase-(racemase)- aktivität kodierende dns-verbindungen.
DE69025845D1 (de) Rekombinante DNA-Expressionsvektoren und DNA-Komponenten, die für eine Acyltransferase-Aktivität von Aspergillus kodieren
DE69120315T2 (de) Rekombinante DNA-Expressionsvektoren und DNA-Zusammensetzungen, die Isopenizillin N-Epimerase-Aktivität kodieren
DE3888386D1 (de) Verfahren zur Herstellung von Proteinen.
HUT47976A (en) Process for producing recombinant expression dna vectors encoding isopenicillin-n-synthetase enzyme of aspergillus nidulans, as well as dna molecules
DE69015737D1 (de) Aminopeptidase.
DE69329540D1 (de) Verfahren zur Herstellung von Proteaseinhibitoren
EP0197797A3 (en) Improved recombinant hosts, their production and use

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee