DE69022297T2 - DNS und ihre Verwendung. - Google Patents

DNS und ihre Verwendung.

Info

Publication number
DE69022297T2
DE69022297T2 DE69022297T DE69022297T DE69022297T2 DE 69022297 T2 DE69022297 T2 DE 69022297T2 DE 69022297 T DE69022297 T DE 69022297T DE 69022297 T DE69022297 T DE 69022297T DE 69022297 T2 DE69022297 T2 DE 69022297T2
Authority
DE
Germany
Prior art keywords
pacap38
dna
protein
protective group
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69022297T
Other languages
English (en)
Other versions
DE69022297D1 (de
Inventor
Haruo Onda
Akira Arimura
Ciharu Kimura
Chieko Kitada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP02039841A external-priority patent/JP3034894B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69022297D1 publication Critical patent/DE69022297D1/de
Publication of DE69022297T2 publication Critical patent/DE69022297T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69022297T 1989-06-20 1990-06-19 DNS und ihre Verwendung. Expired - Fee Related DE69022297T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP15579189 1989-06-20
JP25992489 1989-10-06
JP28477189 1989-11-02
JP02039841A JP3034894B2 (ja) 1989-06-20 1990-02-22 新規ｄｎａおよびその用途

Publications (2)

Publication Number Publication Date
DE69022297D1 DE69022297D1 (de) 1995-10-19
DE69022297T2 true DE69022297T2 (de) 1996-02-22

Family

ID=27460824

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022297T Expired - Fee Related DE69022297T2 (de) 1989-06-20 1990-06-19 DNS und ihre Verwendung.

Country Status (5)

Country Link
US (2) US5198542A (de)
EP (1) EP0404034B1 (de)
AT (1) ATE127844T1 (de)
CA (1) CA2019363C (de)
DE (1) DE69022297T2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486472A (en) * 1990-03-17 1996-01-23 Takeda Chemical Industries, Ltd. Monoclonal antibodies to PACAP
AU651596B2 (en) * 1990-06-05 1994-07-28 Immunex Corporation Type II interleukin-1 receptors
EP0467279A3 (en) * 1990-07-18 1992-08-05 Takeda Chemical Industries, Ltd. Polypeptides having c-amp producing activity
EP0470604A3 (en) * 1990-08-10 1992-12-09 Takeda Chemical Industries, Ltd. Pacap38, proteine with adenylate cyclase activity
US5521069A (en) * 1990-08-10 1996-05-28 Takeda Chemical Industries, Ltd. Genomic DNA exons having exons encoding human pituitary adenylate cyclase activity peptide with 38 amino acids residues(PACAP38) and a promoter thereof
US5623050A (en) * 1991-08-22 1997-04-22 Takeda Chemical Industries, Ltd. Stable polypeptides having c-AMP production enhancing activity and the use thereof
US5695954A (en) * 1993-05-14 1997-12-09 University Of Victoria Innovation & Development Corporation DNA encoding two fish neuropeptides
JPH10505863A (ja) * 1994-09-22 1998-06-09 ジ・アドミニストレーターズ・オブ・ザ・チューレン・エデュケイショナル・ファンド 脳障害の予防および治療のための方法および医薬組成物
US6680295B1 (en) * 1994-09-22 2004-01-20 The Administrators Of The Tulane Educational Fund Method and pharmaceutical composition for prevention and treatment of brain damage
US6165755A (en) * 1997-01-23 2000-12-26 University Of Victoria Innovation And Development Corporation Chicken neuropeptide gene useful for improved poultry production
WO1999051762A1 (en) * 1998-04-03 1999-10-14 Millennium Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
US7048934B2 (en) * 2001-08-30 2006-05-23 Stem Cell Therapeutics Inc. Combined regulation of neural cell production
JP4906231B2 (ja) 2001-09-14 2012-03-28 ステム セル セラピューティクス インコーポレイテッド プロラクチン誘導性の神経幹細胞数の増加ならびにその治療用途
WO2003024471A2 (en) * 2001-09-18 2003-03-27 Stem Cell Therapeutics Inc. Effect of growth hormone and igf-1 on neural stem cells and therapeutic application
CA2492542A1 (en) * 2002-07-30 2004-02-05 Stem Cell Therapeutics Inc. Oligodendrocyte production from multipotent neural stem cells
CA2492442A1 (en) * 2002-07-31 2004-02-05 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
US20060189520A1 (en) 2002-10-22 2006-08-24 Brand Stephen J Treatment of diabetes
US7846898B2 (en) * 2004-02-13 2010-12-07 Stem Cell Therapeutics Corp. Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
JP2008507540A (ja) 2004-07-21 2008-03-13 チューレン ユニバーシティ ヘルス サイエンス センター Ｐａｃａｐ化合物を用いる腎臓機能障害及び多発性骨髄腫の治療
JP2008515818A (ja) 2004-10-07 2008-05-15 ステム セル セラピューティクス コーポレイション 妊娠に関連する化合物の投与による多能性幹細胞の増殖の刺激
KR20080074108A (ko) 2005-09-27 2008-08-12 스템 셀 테라퓨틱스 코포레이션 프로락틴에 의해 조절되는 올리고덴드로사이트 전구체 세포증식
EP2004211A4 (de) * 2006-03-17 2010-07-07 Stem Cell Therapeutics Corp Dosierschemata für lh oder hcg und epo zur behandlung von neurologischen erkrankungen
EP2496245B1 (de) 2009-11-02 2016-07-20 The Administrators Of The Tulane Analoge des pitutären adenylatcyclase-aktivierenden polypeptids (pacap) und verfahren zu ihrer verwendung
AU2016249406B2 (en) 2015-04-16 2021-06-10 H. Lundbeck A/S. Use of anti-PACAP antibodies and antigen binding fragments thereof for treatment, prevention, or inhibition of photophobia
US10913783B2 (en) 2016-04-15 2021-02-09 H. Lundbeck A/S Humanized anti-PACAP antibodies and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939224A (en) * 1987-02-26 1990-07-03 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
US5128242A (en) * 1989-06-19 1992-07-07 The Administrators Of The Tulane Educational Fund Hypothalamic polypeptides with adenylate cyclase stimulating activity

Also Published As

Publication number Publication date
US5198542A (en) 1993-03-30
EP0404034A2 (de) 1990-12-27
EP0404034B1 (de) 1995-09-13
CA2019363A1 (en) 1990-12-20
EP0404034A3 (de) 1991-07-17
US5326860A (en) 1994-07-05
DE69022297D1 (de) 1995-10-19
CA2019363C (en) 2000-05-30
ATE127844T1 (de) 1995-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA CHEMICAL INDUSTRIES, LTD., OSAKA, JP THE AD

8327 Change in the person/name/address of the patent owner

Owner name: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND,

8339 Ceased/non-payment of the annual fee