DE69013296D1 - Einzeldosen mit verzögerter Arzneistofffreigabe. - Google Patents

Einzeldosen mit verzögerter Arzneistofffreigabe.

Info

Publication number
DE69013296D1
DE69013296D1 DE69013296T DE69013296T DE69013296D1 DE 69013296 D1 DE69013296 D1 DE 69013296D1 DE 69013296 T DE69013296 T DE 69013296T DE 69013296 T DE69013296 T DE 69013296T DE 69013296 D1 DE69013296 D1 DE 69013296D1
Authority
DE
Germany
Prior art keywords
drug
release
sustained
drug release
single doses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69013296T
Other languages
English (en)
Other versions
DE69013296T2 (de
DE69013296T3 (de
Inventor
Dale R Brinker
Enrique D Eveline
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27033923&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69013296(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69013296D1 publication Critical patent/DE69013296D1/de
Publication of DE69013296T2 publication Critical patent/DE69013296T2/de
Publication of DE69013296T3 publication Critical patent/DE69013296T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE69013296T 1989-12-01 1990-11-30 Einzeldosen mit verzögerter Arzneistofffreigabe. Expired - Lifetime DE69013296T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44445889A 1989-12-01 1989-12-01
US60515290A 1990-11-02 1990-11-02

Publications (3)

Publication Number Publication Date
DE69013296D1 true DE69013296D1 (de) 1994-11-17
DE69013296T2 DE69013296T2 (de) 1995-02-23
DE69013296T3 DE69013296T3 (de) 2000-11-09

Family

ID=27033923

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69013296T Expired - Lifetime DE69013296T3 (de) 1989-12-01 1990-11-30 Einzeldosen mit verzögerter Arzneistofffreigabe.

Country Status (13)

Country Link
EP (1) EP0430287B2 (de)
JP (1) JP3010562B2 (de)
KR (1) KR100223131B1 (de)
AT (1) ATE112678T1 (de)
AU (1) AU623560B2 (de)
CA (1) CA2031150C (de)
DE (1) DE69013296T3 (de)
DK (1) DK0430287T4 (de)
ES (1) ES2065461T5 (de)
GR (1) GR3034483T3 (de)
IE (1) IE66116B1 (de)
IL (1) IL96311A (de)
PT (1) PT96046B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4127665A1 (de) * 1991-08-22 1993-02-25 Beiersdorf Ag Galenische matrix
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
IL119660A (en) 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US5733578A (en) 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
JP3611456B2 (ja) * 1997-09-30 2005-01-19 日研化学株式会社 テオフィリン徐放性錠剤
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US6419953B1 (en) 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
IL143407A0 (en) * 1998-12-18 2002-04-21 Abbott Lab Controlled release formulation of divalproex sodium
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
KR101216270B1 (ko) 1999-10-29 2012-12-31 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
AU2002227383B2 (en) 2000-10-30 2004-07-08 Euro-Celtique S.A. Controlled release hydrocodone formulations
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
DK1591109T3 (da) * 2004-04-30 2008-10-06 Topotarget Germany Ag Formulering, der omfatter histondeacetylaseinhibitorer, der udviser tofaset frigivelse
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
KR100806541B1 (ko) * 2005-05-11 2008-02-26 한국유나이티드제약 주식회사 아세클로페낙을 함유하는 제어 방출성 제제
WO2009008004A2 (en) * 2007-05-23 2009-01-15 Sun Pharmaceutical Industries Limited Sustained release formulations of divalproex sodium
EP2030613A1 (de) * 2007-08-17 2009-03-04 Abbott GmbH & Co. KG Herstellung von Zusammensetzungen mit hauptsächlich nichtkristallinen eingebetteten Makrolid-Antibiotika

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963451A (en) † 1973-02-15 1976-06-15 United States Steel Corporation Method of forming a high-temperature abrasion-resistant coating on a ferrous metal substrate, and resulting article
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
FI63335B (fi) † 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
DK150008C (da) † 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
US4874614A (en) * 1985-03-25 1989-10-17 Abbott Laboratories Pharmaceutical tableting method
GB2186485B (en) † 1986-02-13 1988-09-07 Ethical Pharma Ltd Slow release formulation
IE63242B1 (en) * 1988-06-24 1995-04-05 Abbott Lab Pharmaceutical granules and tablets made therefrom

Also Published As

Publication number Publication date
DE69013296T2 (de) 1995-02-23
DE69013296T3 (de) 2000-11-09
JPH03190817A (ja) 1991-08-20
EP0430287B2 (de) 2000-07-12
PT96046B (pt) 2001-09-27
IL96311A0 (en) 1991-08-16
EP0430287A2 (de) 1991-06-05
ES2065461T3 (es) 1995-02-16
GR3034483T3 (en) 2000-12-29
KR100223131B1 (ko) 1999-10-15
ATE112678T1 (de) 1994-10-15
ES2065461T5 (es) 2001-01-01
EP0430287B1 (de) 1994-10-12
EP0430287A3 (en) 1991-08-21
AU623560B2 (en) 1992-05-14
CA2031150A1 (en) 1991-06-02
AU6764390A (en) 1991-02-14
IL96311A (en) 1995-05-26
IE904091A1 (en) 1991-06-05
CA2031150C (en) 2000-11-21
DK0430287T4 (da) 2000-10-02
DK0430287T3 (da) 1995-02-27
IE66116B1 (en) 1995-12-13
PT96046A (pt) 1991-09-13
KR910011243A (ko) 1991-08-07
JP3010562B2 (ja) 2000-02-21

Similar Documents

Publication Publication Date Title
DE69013296T2 (de) Einzeldosen mit verzögerter Arzneistofffreigabe.
ATE128863T1 (de) Arzneimittelformulierungen mit verzögerter wirkstoffabgabe.
ATE202473T1 (de) Rasch freisetzende tablettenkerne mit unlöslichen arzneistoffen und mit einem retardüberzug
DE59202537D1 (de) Feste pharmazeutische Retardform.
DE69805001D1 (de) Osmotische darreichungsform mit zwei mantelschichten
DE3868037D1 (de) Pharmazeutische zusammensetzung mit verzoegerter wirkstoffabgabe.
BR9608785A (pt) Forma de dosagem oral contendo como um princípio ativo um ácido mega-3- poli insaturado uso de um ácido ómega-3-poli insaturado e processo de tratar inflamação intestinal
AU7534087A (en) Sustained release pharmaceutical compositions in oral dosage form
DE60103186D1 (de) Stossweise freisetzende Arzneiabgabesysteme
ATE213629T1 (de) Milnacipranhaltige darreichungsform mit verzögerter wirkstoffabgabe
ES2062417T3 (es) Composiciones farmaceuticas de cimetidina.
AU574220B2 (en) Sustained release drug in ter polymer coat (pvc and pvacand pvom)
DE69307807T2 (de) Naproxen-Tabletten mit gesteuerter Wirkstoffabgabe
EP0761209A3 (de) Ranitidinformulierungen mit gesteuerter Freisetzung
DE69103724T2 (de) Pharmazeutische zusammensetzungen mit verzögerter freisetzung zur oralen verabreichung sowie deren herstellungsverfahren.
TH13953A (th) ฟิล์มตัวนำส่งยาใช้เฉพาะที่ในการบำบัดโรคปริทันต์
ATE62409T1 (de) Neue arzneimittelzubereitung mit geregelter verabreichung des aktiven mittels, und deren herstellungsverfahren.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings