DE69001312D1 - Verfahren zur herstellung von anthracyclinonen. - Google Patents

Verfahren zur herstellung von anthracyclinonen.

Info

Publication number
DE69001312D1
DE69001312D1 DE9090103707T DE69001312T DE69001312D1 DE 69001312 D1 DE69001312 D1 DE 69001312D1 DE 9090103707 T DE9090103707 T DE 9090103707T DE 69001312 T DE69001312 T DE 69001312T DE 69001312 D1 DE69001312 D1 DE 69001312D1
Authority
DE
Germany
Prior art keywords
formula
compound
group
vii
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090103707T
Other languages
English (en)
Other versions
DE69001312T2 (de
Inventor
Walter Cabri
Ilaria Candiani
Bernardinis Silvia De
Franco Francalanci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of DE69001312D1 publication Critical patent/DE69001312D1/de
Application granted granted Critical
Publication of DE69001312T2 publication Critical patent/DE69001312T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/38—Quinones containing —CHO or non—quinoid keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catalysts (AREA)
DE9090103707T 1989-03-02 1990-02-26 Verfahren zur herstellung von anthracyclinonen. Expired - Fee Related DE69001312T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898904794A GB8904794D0 (en) 1989-03-02 1989-03-02 Process for preparing anthracyclinones

Publications (2)

Publication Number Publication Date
DE69001312D1 true DE69001312D1 (de) 1993-05-19
DE69001312T2 DE69001312T2 (de) 1993-07-22

Family

ID=10652605

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9090103707T Expired - Fee Related DE69001312T2 (de) 1989-03-02 1990-02-26 Verfahren zur herstellung von anthracyclinonen.

Country Status (26)

Country Link
US (1) US5180758A (de)
EP (1) EP0385354B1 (de)
JP (1) JP2717023B2 (de)
KR (1) KR0171047B1 (de)
CN (1) CN1028518C (de)
AT (1) ATE88173T1 (de)
AU (1) AU636134B2 (de)
CA (1) CA2047748C (de)
CZ (1) CZ278804B6 (de)
DE (1) DE69001312T2 (de)
DK (1) DK0385354T3 (de)
ES (1) ES2055189T3 (de)
FI (1) FI92687C (de)
GB (1) GB8904794D0 (de)
HU (1) HU207705B (de)
IE (1) IE63571B1 (de)
IL (1) IL93559A (de)
MY (1) MY105260A (de)
NO (1) NO174546C (de)
NZ (1) NZ232681A (de)
PT (1) PT93317B (de)
RU (1) RU2077526C1 (de)
SK (1) SK278225B6 (de)
WO (1) WO1990009974A1 (de)
YU (1) YU47556B (de)
ZA (1) ZA901542B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ319799A0 (en) * 1999-10-01 1999-10-28 Institute Of Drug Technology Australia Limited Chemical methods
JP4688315B2 (ja) * 2001-02-28 2011-05-25 メルシャン株式会社 ４−デメトキシダウノマイシノンの製造
US7053191B2 (en) * 2003-05-21 2006-05-30 Solux Corporation Method of preparing 4-R-substituted 4-demethoxydaunorubicin
US20060047108A1 (en) * 2004-08-23 2006-03-02 Marco Villa Synthesis of idarubicin aglycone
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US8846882B2 (en) 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation

Also Published As

Publication number Publication date
JP2717023B2 (ja) 1998-02-18
NO174546B (no) 1994-02-14
YU39990A (en) 1991-10-31
NO913382L (no) 1991-08-28
NO174546C (no) 1994-05-25
ES2055189T3 (es) 1994-08-16
DK0385354T3 (da) 1993-05-17
CZ278804B6 (en) 1994-07-13
FI92687B (fi) 1994-09-15
CS9000958A2 (en) 1991-08-13
NO913382D0 (no) 1991-08-28
CA2047748A1 (en) 1990-09-03
CN1028518C (zh) 1995-05-24
HU902357D0 (en) 1991-11-28
PT93317A (pt) 1990-11-07
DE69001312T2 (de) 1993-07-22
IL93559A0 (en) 1990-11-29
PT93317B (pt) 1996-01-31
IL93559A (en) 1994-06-24
AU636134B2 (en) 1993-04-22
ATE88173T1 (de) 1993-04-15
GB8904794D0 (en) 1989-04-12
SK278225B6 (en) 1996-04-03
CA2047748C (en) 1999-05-18
FI914053A0 (fi) 1991-08-28
IE63571B1 (en) 1995-05-17
WO1990009974A1 (en) 1990-09-07
MY105260A (en) 1994-09-30
NZ232681A (en) 1991-04-26
AU5184890A (en) 1990-09-26
EP0385354B1 (de) 1993-04-14
KR900014286A (ko) 1990-10-23
US5180758A (en) 1993-01-19
CN1045259A (zh) 1990-09-12
HU207705B (en) 1993-05-28
JPH04503803A (ja) 1992-07-09
YU47556B (sh) 1995-10-03
FI92687C (fi) 1994-12-27
IE900700L (en) 1990-09-02
ZA901542B (en) 1990-12-28
KR0171047B1 (ko) 1999-03-30
RU2077526C1 (ru) 1997-04-20
HUT58033A (en) 1992-01-28
EP0385354A1 (de) 1990-09-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN S.P.A., MAILAND/MILANO, IT

8339 Ceased/non-payment of the annual fee